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• W2016992005 abstract "There is currently no consensus on the evolutionary origin of eukaryotes. In the search of the ancestors of eukaryotes, we analyzed the phylogeny of 46 genomes, including those of 2 eukaryotes, 8 archaea, and 36 eubacteria. To avoid the effects of gene duplications, we used inparalog pairs of genes with orthologous relationships. First, we grouped these inparalogs into the functional categories of the nucleus, cytoplasm, and mitochondria. Next, we counted the sister groups of eukaryotes in prokaryotic phyla and plotted them on a standard phylogenetic tree. Finally, we used Pearson’s chi-square test to estimate the origin of the genomes from specific prokaryotic ancestors. The results suggest the eukaryotic nuclear genome descends from an archaea that was neither euryarchaeota nor crenarchaeota and that the mitochondrial genome descends from α-proteobacteria. In contrast, genes related to the cytoplasm do not appear to originate from a specific group of prokaryotes." @default.
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• W2016992005 date "2008-01-01" @default.
• W2016992005 modified "2023-09-27" @default.
• W2016992005 title "Comprehensive analysis of the origin of eukaryotic genomes" @default.
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• W2016992005 doi "https://doi.org/10.1266/ggs.83.285" @default.
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