FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016992017> ?p ?o ?g. }

• W2016992017 endingPage "47" @default.
• W2016992017 startingPage "41" @default.
• W2016992017 abstract "Technical grade DDT, a commonly used pesticide, contains 20% of the o,p′-DDT isomer. It alters the activity of hepatic mixed function oxidase and induces expression of cytochrome P450 such as 3A subfamilies. In the present study, we analyzed the effects of o,p′-DDT on CYP3A4 gene expression in HepG2 cells. Treatment with o,p′-DDT dose-dependently increased levels of CYP3A4 mRNA and the immunoreactive protein, by 13- and 3.8-fold, respectively, relative to untreated cultures. Treatment with actinomycin D blocked the o,p′-DDT-induced increase in CYP3A4 mRNA levels. These findings demonstrate that this insecticide is able to induce CYP3A4 transcription and may play an important role in the modulation of endogenous hormones and xenobiótic metabolism." @default.
• W2016992017 created "2016-06-24" @default.
• W2016992017 creator A5019661410 @default.
• W2016992017 creator A5087085889 @default.
• W2016992017 date "2005-05-16" @default.
• W2016992017 modified "2023-09-27" @default.
• W2016992017 title "Transcriptional induction of CYP3A4 by o,p′-DDT in HepG2 cells" @default.
• W2016992017 cites W1635676915 @default.
• W2016992017 cites W1775964807 @default.
• W2016992017 cites W1972996926 @default.
• W2016992017 cites W1979084622 @default.
• W2016992017 cites W1997365504 @default.
• W2016992017 cites W2002044083 @default.
• W2016992017 cites W2006998778 @default.
• W2016992017 cites W2008329731 @default.
• W2016992017 cites W2013030667 @default.
• W2016992017 cites W2022600795 @default.
• W2016992017 cites W2038478895 @default.
• W2016992017 cites W2048960889 @default.
• W2016992017 cites W2052006868 @default.
• W2016992017 cites W2066503178 @default.
• W2016992017 cites W2075327595 @default.
• W2016992017 cites W2075920649 @default.
• W2016992017 cites W2078510487 @default.
• W2016992017 cites W2078858903 @default.
• W2016992017 cites W2079676828 @default.
• W2016992017 cites W2084462922 @default.
• W2016992017 cites W2107277218 @default.
• W2016992017 cites W2112321255 @default.
• W2016992017 cites W2114918609 @default.
• W2016992017 cites W2115159575 @default.
• W2016992017 cites W2115210365 @default.
• W2016992017 cites W2136695719 @default.
• W2016992017 cites W2155268095 @default.
• W2016992017 cites W2187718168 @default.
• W2016992017 cites W2327807854 @default.
• W2016992017 cites W2465379795 @default.
• W2016992017 doi "https://doi.org/10.1016/j.toxlet.2005.01.003" @default.
• W2016992017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15795092" @default.
• W2016992017 hasPublicationYear "2005" @default.
• W2016992017 type Work @default.
• W2016992017 sameAs 2016992017 @default.
• W2016992017 citedByCount "38" @default.
• W2016992017 countsByYear W20169920172012 @default.
• W2016992017 countsByYear W20169920172013 @default.
• W2016992017 countsByYear W20169920172014 @default.
• W2016992017 countsByYear W20169920172016 @default.
• W2016992017 countsByYear W20169920172017 @default.
• W2016992017 countsByYear W20169920172018 @default.
• W2016992017 countsByYear W20169920172019 @default.
• W2016992017 countsByYear W20169920172020 @default.
• W2016992017 countsByYear W20169920172021 @default.
• W2016992017 crossrefType "journal-article" @default.
• W2016992017 hasAuthorship W2016992017A5019661410 @default.
• W2016992017 hasAuthorship W2016992017A5087085889 @default.
• W2016992017 hasConcept C104317684 @default.
• W2016992017 hasConcept C105580179 @default.
• W2016992017 hasConcept C109650736 @default.
• W2016992017 hasConcept C126322002 @default.
• W2016992017 hasConcept C134018914 @default.
• W2016992017 hasConcept C138885662 @default.
• W2016992017 hasConcept C150194340 @default.
• W2016992017 hasConcept C16613235 @default.
• W2016992017 hasConcept C179926584 @default.
• W2016992017 hasConcept C181199279 @default.
• W2016992017 hasConcept C185592680 @default.
• W2016992017 hasConcept C2780768313 @default.
• W2016992017 hasConcept C2910828019 @default.
• W2016992017 hasConcept C38485361 @default.
• W2016992017 hasConcept C41895202 @default.
• W2016992017 hasConcept C526171541 @default.
• W2016992017 hasConcept C55493867 @default.
• W2016992017 hasConcept C62231903 @default.
• W2016992017 hasConcept C71315377 @default.
• W2016992017 hasConcept C71924100 @default.
• W2016992017 hasConcept C86803240 @default.
• W2016992017 hasConceptScore W2016992017C104317684 @default.
• W2016992017 hasConceptScore W2016992017C105580179 @default.
• W2016992017 hasConceptScore W2016992017C109650736 @default.
• W2016992017 hasConceptScore W2016992017C126322002 @default.
• W2016992017 hasConceptScore W2016992017C134018914 @default.
• W2016992017 hasConceptScore W2016992017C138885662 @default.
• W2016992017 hasConceptScore W2016992017C150194340 @default.
• W2016992017 hasConceptScore W2016992017C16613235 @default.
• W2016992017 hasConceptScore W2016992017C179926584 @default.
• W2016992017 hasConceptScore W2016992017C181199279 @default.
• W2016992017 hasConceptScore W2016992017C185592680 @default.
• W2016992017 hasConceptScore W2016992017C2780768313 @default.
• W2016992017 hasConceptScore W2016992017C2910828019 @default.
• W2016992017 hasConceptScore W2016992017C38485361 @default.
• W2016992017 hasConceptScore W2016992017C41895202 @default.
• W2016992017 hasConceptScore W2016992017C526171541 @default.
• W2016992017 hasConceptScore W2016992017C55493867 @default.
• W2016992017 hasConceptScore W2016992017C62231903 @default.
• W2016992017 hasConceptScore W2016992017C71315377 @default.
• W2016992017 hasConceptScore W2016992017C71924100 @default.
• W2016992017 hasConceptScore W2016992017C86803240 @default.
• W2016992017 hasIssue "1" @default.

• next