FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016993324> ?p ?o ?g. }

• W2016993324 endingPage "1658" @default.
• W2016993324 startingPage "1641" @default.
• W2016993324 abstract "The Swi6 transcription factor, required for G1/S-specific gene expression in Saccharomyces cerevisiae, is highly phosphorylated in vivo. Within the limits of resolution of the peptide analysis, the synchrony, and the time intervals tested, serine 160 appears to be the only site of phosphorylation in Swi6 that varies during the cell cycle. Serine 160 resides within a Cdc28 consensus phosphorylation site and its phosphorylation occurs at about the time of maximal transcription of Swi6- and Cdc28-dependent genes containing SCB or MCB elements. However, phosphorylation at this site is not Cdc28-dependent, nor does it control G1/S-specific transcription. The role of the cell cycle-regulated phosphorylation is to control the subcellular localization of Swi6. Phosphorylation of serine 160 persists from late G1 until late M phase, and Swi6 is predominantly cytoplasmic during this time. Aspartate substitution for serine 160 inhibits nuclear localization throughout the cycle. Swi6 enters the nucleus late in M phase and throughout G1, when serine 160 is hypophosphorylated. Alanine substitution at position 160 allows nuclear entry of Swi6 throughout the cell cycle. GFP fusions with the N-terminal one-third of Swi6 display the same cell cycle-regulated localization as Swi6." @default.
• W2016993324 created "2016-06-24" @default.
• W2016993324 creator A5060020867 @default.
• W2016993324 creator A5085443902 @default.
• W2016993324 creator A5090745470 @default.
• W2016993324 date "1995-12-01" @default.
• W2016993324 modified "2023-09-30" @default.
• W2016993324 title "Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization." @default.
• W2016993324 cites W1528493806 @default.
• W2016993324 cites W1871042223 @default.
• W2016993324 cites W1920670914 @default.
• W2016993324 cites W1967724361 @default.
• W2016993324 cites W1973635919 @default.
• W2016993324 cites W1974905046 @default.
• W2016993324 cites W1979213543 @default.
• W2016993324 cites W1984750219 @default.
• W2016993324 cites W1985578429 @default.
• W2016993324 cites W1989216170 @default.
• W2016993324 cites W1989313041 @default.
• W2016993324 cites W1997408971 @default.
• W2016993324 cites W2014293907 @default.
• W2016993324 cites W2019894624 @default.
• W2016993324 cites W2023536598 @default.
• W2016993324 cites W2028801502 @default.
• W2016993324 cites W2031013242 @default.
• W2016993324 cites W2036931150 @default.
• W2016993324 cites W2042591463 @default.
• W2016993324 cites W2043038579 @default.
• W2016993324 cites W2045737218 @default.
• W2016993324 cites W2049294948 @default.
• W2016993324 cites W2052881693 @default.
• W2016993324 cites W2055475376 @default.
• W2016993324 cites W2057129283 @default.
• W2016993324 cites W2057493866 @default.
• W2016993324 cites W2062319807 @default.
• W2016993324 cites W2064249717 @default.
• W2016993324 cites W2064767087 @default.
• W2016993324 cites W2066599845 @default.
• W2016993324 cites W2068681052 @default.
• W2016993324 cites W2078906089 @default.
• W2016993324 cites W2091038230 @default.
• W2016993324 cites W2091501337 @default.
• W2016993324 cites W2094923559 @default.
• W2016993324 cites W2095571979 @default.
• W2016993324 cites W2104110677 @default.
• W2016993324 cites W2106126132 @default.
• W2016993324 cites W2109413613 @default.
• W2016993324 cites W2111784788 @default.
• W2016993324 cites W2123930515 @default.
• W2016993324 cites W2125563063 @default.
• W2016993324 cites W2125862386 @default.
• W2016993324 cites W2140660011 @default.
• W2016993324 cites W2140682015 @default.
• W2016993324 cites W2141653943 @default.
• W2016993324 cites W2144892831 @default.
• W2016993324 cites W2152125010 @default.
• W2016993324 cites W2159137674 @default.
• W2016993324 cites W2169333620 @default.
• W2016993324 cites W2742310719 @default.
• W2016993324 doi "https://doi.org/10.1091/mbc.6.12.1641" @default.
• W2016993324 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/301322" @default.
• W2016993324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8590795" @default.
• W2016993324 hasPublicationYear "1995" @default.
• W2016993324 type Work @default.
• W2016993324 sameAs 2016993324 @default.
• W2016993324 citedByCount "91" @default.
• W2016993324 countsByYear W20169933242012 @default.
• W2016993324 countsByYear W20169933242013 @default.
• W2016993324 countsByYear W20169933242014 @default.
• W2016993324 countsByYear W20169933242015 @default.
• W2016993324 countsByYear W20169933242016 @default.
• W2016993324 countsByYear W20169933242017 @default.
• W2016993324 countsByYear W20169933242018 @default.
• W2016993324 countsByYear W20169933242020 @default.
• W2016993324 countsByYear W20169933242021 @default.
• W2016993324 countsByYear W20169933242022 @default.
• W2016993324 countsByYear W20169933242023 @default.
• W2016993324 crossrefType "journal-article" @default.
• W2016993324 hasAuthorship W2016993324A5060020867 @default.
• W2016993324 hasAuthorship W2016993324A5085443902 @default.
• W2016993324 hasAuthorship W2016993324A5090745470 @default.
• W2016993324 hasBestOaLocation W20169933242 @default.
• W2016993324 hasConcept C104317684 @default.
• W2016993324 hasConcept C11960822 @default.
• W2016993324 hasConcept C120504264 @default.
• W2016993324 hasConcept C153911025 @default.
• W2016993324 hasConcept C190062978 @default.
• W2016993324 hasConcept C2776414213 @default.
• W2016993324 hasConcept C2780114586 @default.
• W2016993324 hasConcept C29537977 @default.
• W2016993324 hasConcept C55493867 @default.
• W2016993324 hasConcept C86339819 @default.
• W2016993324 hasConcept C86803240 @default.
• W2016993324 hasConcept C95444343 @default.
• W2016993324 hasConceptScore W2016993324C104317684 @default.
• W2016993324 hasConceptScore W2016993324C11960822 @default.
• W2016993324 hasConceptScore W2016993324C120504264 @default.
• W2016993324 hasConceptScore W2016993324C153911025 @default.

• next