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- W2016993345 abstract "We synthesized several vitamin E analogues containing oxygenated functional groups in place of the 8-methyl group which is common to all the natural vitamin E congeners, based on the hypothesis that the methyl group might be metabolically oxidized to produce active forms which might have specific functions other than the antioxidant function. All the vitamin E analogues examined had antioxidant activity. 8-[6-Hydroxy-2,5,7-trimethyl]-2-(4,8,12-trimethyltridecanyl)chroman'methanol (1d) and 2,5,7-trimethyl-2-(4,8,12-trimethyltridecanyl)chroman-6-ol (4d) showed similar activity to α-tocopherol. 6-Hydroxy-2,5,7-trimethyl-2-(4,8,12-trimethyltridecanyl) chroman-8-carbaldehyde (2d) and 6-hydroxy-2,5,7-trimethyl-2-(4,8,12-trimethyltridecanyl)chroman-8-carboxylic acid (3d) showed weaker activity than α-tocopherol, but their duration of action, especially that of 3d was considerably longer." @default.
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- W2016993345 date "1996-01-01" @default.
- W2016993345 modified "2023-10-02" @default.
- W2016993345 title "Synthesis of Vitamin E Analogues: Possible Active Forms of Vitamin E" @default.
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- W2016993345 doi "https://doi.org/10.1002/ardp.19963290106" @default.
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