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• W2016995764 abstract "The aims of the current work were to evaluate the hepatoprotective effect of calendula flowers and/or thyme leave extracts on aflatoxins (AFs)-induced oxidative stress, genotoxicity and alteration of p53 bax and bcl2 gene expressions. Eighty male Sprague–Dawley rats were divided into eight equal groups including: the control group, the group fed AFs-contaminated diet (2.5 mg/kg diet) for 5 weeks, the groups treated orally with thyme and/or calendula extract (0.5 g/kg b.w) for 6 weeks and the groups pretreated orally with thyme and/or calendula extract 1 week before and during AFs treatment for further 5 weeks. Blood, liver and bone marrow samples were collected for biochemical analysis, gene expression, DNA fragmentation and micronucleus assay. The results showed that AFs induced significant alterations in oxidative stress markers, increased serum AFP and inflammatory cytokine, percentage of DNA fragmentation, the expression of pro-apoptotic gene p53 and bax accompanied with a decrease in the expression of bcl2. Animals treated with the extracts 1 week before AFs treatment showed a significant decrease in oxidative damage markers, micronucleated cells, DNA fragmentation and modulation of the expression of pro-apoptotic genes. These results suggested that both calendula and thyme extracts had anti-genotoxic effects due to their higher content of total phenolic compounds." @default.
• W2016995764 created "2016-06-24" @default.
• W2016995764 creator A5017728213 @default.
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• W2016995764 creator A5089006287 @default.
• W2016995764 date "2013-10-06" @default.
• W2016995764 modified "2023-10-14" @default.
• W2016995764 title "Ameliorative effects of thyme and calendula extracts alone or in combination against aflatoxins-induced oxidative stress and genotoxicity in rat liver" @default.
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• W2016995764 cites W1616982859 @default.
• W2016995764 cites W1966723685 @default.
• W2016995764 cites W1971205969 @default.
• W2016995764 cites W1975477222 @default.
• W2016995764 cites W1978559001 @default.
• W2016995764 cites W1980657599 @default.
• W2016995764 cites W1982635838 @default.
• W2016995764 cites W1983397109 @default.
• W2016995764 cites W1988995857 @default.
• W2016995764 cites W1989592329 @default.
• W2016995764 cites W1991267076 @default.
• W2016995764 cites W1994272912 @default.
• W2016995764 cites W1994318934 @default.
• W2016995764 cites W1995190878 @default.
• W2016995764 cites W1996492965 @default.
• W2016995764 cites W2001273173 @default.
• W2016995764 cites W2002798549 @default.
• W2016995764 cites W2003452322 @default.
• W2016995764 cites W2009965236 @default.
• W2016995764 cites W2011422760 @default.
• W2016995764 cites W2013186012 @default.
• W2016995764 cites W2014003988 @default.
• W2016995764 cites W2016367172 @default.
• W2016995764 cites W2019414411 @default.
• W2016995764 cites W2019518246 @default.
• W2016995764 cites W2019971469 @default.
• W2016995764 cites W2024423150 @default.
• W2016995764 cites W2028052424 @default.
• W2016995764 cites W2037858698 @default.
• W2016995764 cites W2039573559 @default.
• W2016995764 cites W2042769296 @default.
• W2016995764 cites W2042830692 @default.
• W2016995764 cites W2045958996 @default.
• W2016995764 cites W2052306795 @default.
• W2016995764 cites W2053990128 @default.
• W2016995764 cites W2061322364 @default.
• W2016995764 cites W2067123933 @default.
• W2016995764 cites W2068597196 @default.
• W2016995764 cites W2069222458 @default.
• W2016995764 cites W2069866574 @default.
• W2016995764 cites W2071417758 @default.
• W2016995764 cites W2072113837 @default.
• W2016995764 cites W2073806713 @default.
• W2016995764 cites W2073881800 @default.
• W2016995764 cites W2075994312 @default.
• W2016995764 cites W2076182668 @default.
• W2016995764 cites W2077059762 @default.
• W2016995764 cites W2082333273 @default.
• W2016995764 cites W2082727082 @default.
• W2016995764 cites W2088888066 @default.
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• W2016995764 cites W2116117473 @default.
• W2016995764 cites W2118988881 @default.
• W2016995764 cites W2121242739 @default.
• W2016995764 cites W2121417474 @default.
• W2016995764 cites W2122627366 @default.
• W2016995764 cites W2129890254 @default.
• W2016995764 cites W2136210930 @default.
• W2016995764 cites W2136554898 @default.
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• W2016995764 cites W2163540132 @default.
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• W2016995764 doi "https://doi.org/10.1007/s10616-013-9598-7" @default.
• W2016995764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3973790" @default.
• W2016995764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24096837" @default.
• W2016995764 hasPublicationYear "2013" @default.
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