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- W2017001433 abstract "Burkitt lymphoma cells carrying either a rearranged or unrearranged c-myc oncogene were examined with the use of probes from the 5' exon and for the second and third exon of the oncogene. The results indicate that the normal c-myc gene on chromosome 8 and the 5' noncoding and 3' coding segments of the c-myc oncogene separated by the chromosomal translocation are under different transcriptional control in the lymphoma cells. Burkitt lymphoma cells carrying a translocated but unrearranged c-myc oncogene express normal c-myc transcripts. In contrast, lymphoma cells carrying a c-myc gene rearranged head to head with the immunoglobulin constant mu region gene express c-myc transcripts lacking the normal untranslated leader." @default.
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- W2017001433 date "1983-10-28" @default.
- W2017001433 modified "2023-09-27" @default.
- W2017001433 title "Differential Expression of the Translocated and the Untranslocated c- <i>myc</i> Oncogene in Burkitt Lymphoma" @default.
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- W2017001433 doi "https://doi.org/10.1126/science.6414084" @default.
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