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- W2017005544 abstract "One third of all deaths worldwide in 2008 were caused by cardiovascular diseases (CVD), and the incidence of CVD related deaths rises ever more. Thus, improved imaging techniques and modalities are needed for the evaluation of cardiac morphology and function. Cardiac magnetic resonance imaging (CMRI) is a minimally invasive technique that is increasingly important due to its high spatial and temporal resolution, its high soft tissue contrast and its ability of functional and quantitative imaging. It is widely accepted as the gold standard of cardiac functional analysis. In the short period of small animal MRI, remarkable progress has been achieved concerning new, fast imaging schemes as well as purpose-built equipment. Dedicated small animal scanners allow for tapping the full potential of recently developed animal models of cardiac disease. In this paper, we review state-of-the-art cardiac magnetic resonance imaging techniques and applications in small animals at ultra-high fields (UHF). Ein Drittel aller Todesfälle weltweit wurden 2008 durch kardiovaskuläre Krankheiten verursacht, und deren Inzidenz häuft sich mehr und mehr. Daher werden verbesserte Bildgebungstechniken und Modalitäten für die Auswertung kardialer Morphologie und Funktion benötigt. Die kardiale Magnetresonanztomographie (MRT) ist eine minimal-invasive Technik, die aufgrund ihrer hohen örtlichen und zeitlichen Auflösung, ihres hohen Weichteilkontrastes und ihrer Fähigkeit zur funktionellen und quantitativen Bildgebung immer wichtiger wird. Sie hat sich zu einem Goldstandard für die funktionelle Untersuchung von Herzkrankheiten entwickelt. In der kurzen Zeitspanne der Kleintier-MRT wurden bemerkenswerte Fortschritte erzielt hinsichtlich neuer, schneller Bildgebungstechniken und speziell angefertigter Hardware. Dedizierte Kleintierscanner ermöglichen es, das Potenzial neu entwickelter Tiermodelle kardialer Krankheiten voll auszuschöpfen. In diesem Review werden State-of-the-Art-MRT-Techniken und Anwendungen zur Untersuchung des Herzens an Kleintieren bei Ultrahochfeld vorgestellt." @default.
- W2017005544 created "2016-06-24" @default.
- W2017005544 creator A5000123451 @default.
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- W2017005544 creator A5005613058 @default.
- W2017005544 creator A5074124682 @default.
- W2017005544 date "2014-12-01" @default.
- W2017005544 modified "2023-10-01" @default.
- W2017005544 title "Pre-clinical functional Magnetic Resonance Imaging part II: The heart" @default.
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