FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017006581> ?p ?o ?g. }

• W2017006581 endingPage "250" @default.
• W2017006581 startingPage "245" @default.
• W2017006581 abstract "The human aromatase gene (P450arom) is widely expressed, albeit in a tissue-specific manner. In the present study, we measured aromatase activity and investigated the transcribed and translated products of the P450arom gene before and after Epstein–Barr virus (EBV) transformation in peripheral blood lymphocytes (PBLs) from normal individuals. Aromatase activity was determined by [3H]-Δ4-androstenedione (A) to [3H]-estrone (E1) conversion. Cellular total RNA and protein lysates were subjected to RT-PCR and Western analysis, respectively. Rapid amplification of cDNA ends (RACE) was used for the detection of novel 5′-untranslated ends of the P450arom mRNA, which were subsequently sequenced and compared to the known transcripts of this gene. In untransformed PBLs, two known variants of exon 1 of the P450arom gene were expressed, corresponding to promoters PI.3 and PII, or 1c and 1d, respectively. In EBV-transformed PBLs, a cryptic splice site was revealed and a new 5′-untranslated product was found. RNase protection assay confirmed that this splice variant is not a RACE artifact. The 53 K P450arom protein was detectable in PBLs both before and after EBV transformation. We conclude that (i) the P450arom mRNA is present in human PBLs and (ii) EBV transformation of the latter leads to novel alternative splicing of the 5′ end of this gene." @default.
• W2017006581 created "2016-06-24" @default.
• W2017006581 creator A5021561960 @default.
• W2017006581 creator A5024202469 @default.
• W2017006581 creator A5031897654 @default.
• W2017006581 creator A5037724688 @default.
• W2017006581 creator A5091426157 @default.
• W2017006581 date "1998-03-01" @default.
• W2017006581 modified "2023-09-24" @default.
• W2017006581 title "P450arom gene expression in peripheral blood lymphocytes: Identification of a cryptic splice site for exon-1 afterEpstein–Barr virus transformation" @default.
• W2017006581 cites W1547162940 @default.
• W2017006581 cites W1548912548 @default.
• W2017006581 cites W1559018455 @default.
• W2017006581 cites W1965857260 @default.
• W2017006581 cites W1975076319 @default.
• W2017006581 cites W1977843428 @default.
• W2017006581 cites W1980669204 @default.
• W2017006581 cites W1988296914 @default.
• W2017006581 cites W1992246810 @default.
• W2017006581 cites W1992640917 @default.
• W2017006581 cites W2004632365 @default.
• W2017006581 cites W2017374476 @default.
• W2017006581 cites W2042157811 @default.
• W2017006581 cites W2048315476 @default.
• W2017006581 cites W2055252675 @default.
• W2017006581 cites W2061481377 @default.
• W2017006581 cites W2064533401 @default.
• W2017006581 cites W2064659001 @default.
• W2017006581 cites W2078621291 @default.
• W2017006581 cites W2092547974 @default.
• W2017006581 cites W2093997497 @default.
• W2017006581 cites W2105604113 @default.
• W2017006581 cites W2106470286 @default.
• W2017006581 cites W2142338219 @default.
• W2017006581 doi "https://doi.org/10.1016/s0960-0760(97)00193-3" @default.
• W2017006581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9618025" @default.
• W2017006581 hasPublicationYear "1998" @default.
• W2017006581 type Work @default.
• W2017006581 sameAs 2017006581 @default.
• W2017006581 citedByCount "10" @default.
• W2017006581 countsByYear W20170065812012 @default.
• W2017006581 countsByYear W20170065812020 @default.
• W2017006581 crossrefType "journal-article" @default.
• W2017006581 hasAuthorship W2017006581A5021561960 @default.
• W2017006581 hasAuthorship W2017006581A5024202469 @default.
• W2017006581 hasAuthorship W2017006581A5031897654 @default.
• W2017006581 hasAuthorship W2017006581A5037724688 @default.
• W2017006581 hasAuthorship W2017006581A5091426157 @default.
• W2017006581 hasBestOaLocation W20170065811 @default.
• W2017006581 hasConcept C104317684 @default.
• W2017006581 hasConcept C105580179 @default.
• W2017006581 hasConcept C121608353 @default.
• W2017006581 hasConcept C150194340 @default.
• W2017006581 hasConcept C153911025 @default.
• W2017006581 hasConcept C159047783 @default.
• W2017006581 hasConcept C187882448 @default.
• W2017006581 hasConcept C2522874641 @default.
• W2017006581 hasConcept C2776166826 @default.
• W2017006581 hasConcept C36823959 @default.
• W2017006581 hasConcept C530470458 @default.
• W2017006581 hasConcept C54355233 @default.
• W2017006581 hasConcept C86803240 @default.
• W2017006581 hasConcept C89604277 @default.
• W2017006581 hasConceptScore W2017006581C104317684 @default.
• W2017006581 hasConceptScore W2017006581C105580179 @default.
• W2017006581 hasConceptScore W2017006581C121608353 @default.
• W2017006581 hasConceptScore W2017006581C150194340 @default.
• W2017006581 hasConceptScore W2017006581C153911025 @default.
• W2017006581 hasConceptScore W2017006581C159047783 @default.
• W2017006581 hasConceptScore W2017006581C187882448 @default.
• W2017006581 hasConceptScore W2017006581C2522874641 @default.
• W2017006581 hasConceptScore W2017006581C2776166826 @default.
• W2017006581 hasConceptScore W2017006581C36823959 @default.
• W2017006581 hasConceptScore W2017006581C530470458 @default.
• W2017006581 hasConceptScore W2017006581C54355233 @default.
• W2017006581 hasConceptScore W2017006581C86803240 @default.
• W2017006581 hasConceptScore W2017006581C89604277 @default.
• W2017006581 hasFunder F4320312012 @default.
• W2017006581 hasFunder F4320322436 @default.
• W2017006581 hasFunder F4320332161 @default.
• W2017006581 hasIssue "5-6" @default.
• W2017006581 hasLocation W20170065811 @default.
• W2017006581 hasLocation W20170065812 @default.
• W2017006581 hasOpenAccess W2017006581 @default.
• W2017006581 hasPrimaryLocation W20170065811 @default.
• W2017006581 hasRelatedWork W1966427723 @default.
• W2017006581 hasRelatedWork W1966512561 @default.
• W2017006581 hasRelatedWork W1985881345 @default.
• W2017006581 hasRelatedWork W2009810944 @default.
• W2017006581 hasRelatedWork W2029158055 @default.
• W2017006581 hasRelatedWork W2029451197 @default.
• W2017006581 hasRelatedWork W2056172754 @default.
• W2017006581 hasRelatedWork W2095293288 @default.
• W2017006581 hasRelatedWork W2383713371 @default.
• W2017006581 hasRelatedWork W2185245252 @default.
• W2017006581 hasVolume "64" @default.
• W2017006581 isParatext "false" @default.
• W2017006581 isRetracted "false" @default.

• next