FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017007926> ?p ?o ?g. }

• W2017007926 endingPage "55" @default.
• W2017007926 startingPage "52" @default.
• W2017007926 abstract "This study aimed to assess surgical workload and risk factors for gastrointestinal bleeding in patients on warfarin admitted to a hospital.Data was collected for all warfarinised patients admitted between April 2005 and October 2007 with gastrointestinal bleeding.A total of 30 patients (average 80 years) were recorded. Indications for warfarin therapy were atrial fibrillation (80%), mechanical heart valve (6.67%) and embolic disease (13.33%). Fifty percent were admitted with an INR above therapeutic range and of these patients, 83% were on one or more medications known to potentiate the anti-coagulation effect of warfarin. Nine patients were also taking anti-platelet medication. Five of these nine had an admission INR within the intended therapeutic range. Thirteen patients received blood transfusions and had a significantly higher (p<0.05) INR (average 9) than the 17 patients not requiring transfusion (average 2.8). The average cost of transfusion per patient was pound470. None of the patients required acute surgical intervention. The average length of stay was 7 days, at a total cost of pound1444 per patient. Investigations found the cause of bleeding to be diverticulosis in 9 patients and neoplastic disease in 4 patients. Almost half of the patients received no investigation due to risks from co-morbidity.Uncontrolled anti-coagulation, polypharmacy and age were overwhelming risk factors for major gastrointestinal bleeding. Our results show that adding anti-platelet therapy has to be clearly justified against the increased risk of bleeding. Cost to the surgical department was high and no patients required surgical or radiological intervention. WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Warfarin is an important drug, but the complications of its use are difficult and expensive to deal with. Warfarin use is a risk factor for haemorrhage, and this commonly involves the gastrointestinal tract. The use of warfarin is set to increase as the population ages and atrial fibrillation and other cardiovascular risk factors become more prevalent. Consequently, one can expect a rise in warfarin-related gastrointestinal haemorrhage. WHAT DOES THIS ARTICLE ADD?: Our study aimed to assess the burden of gastrointestinal haemorrhage secondary to warfarin on our surgical department (which was high), and also to assess what the risk factors for haemorrhage for patients on warfarin. One of the risk factors we uncovered was polypharmacy, particularly involving anti-platelets e.g. aspirin. We highlight the need for further guidance with regards to managing patients on warfarin, and suggest possible solutions to the problems uncovered." @default.
• W2017007926 created "2016-06-24" @default.
• W2017007926 creator A5016764433 @default.
• W2017007926 creator A5025044096 @default.
• W2017007926 creator A5052291824 @default.
• W2017007926 creator A5067451949 @default.
• W2017007926 date "2010-01-01" @default.
• W2017007926 modified "2023-09-29" @default.
• W2017007926 title "Surgical workload, risk factors and complications in patients on warfarin with gastrointestinal bleeding" @default.
• W2017007926 cites W1992944164 @default.
• W2017007926 cites W2017988940 @default.
• W2017007926 cites W2038817894 @default.
• W2017007926 cites W2054740753 @default.
• W2017007926 cites W2060630424 @default.
• W2017007926 cites W2076759080 @default.
• W2017007926 cites W2114775432 @default.
• W2017007926 cites W2119221555 @default.
• W2017007926 cites W2130728413 @default.
• W2017007926 cites W2132505348 @default.
• W2017007926 cites W2156613835 @default.
• W2017007926 cites W2170786340 @default.
• W2017007926 cites W2171508983 @default.
• W2017007926 cites W2499224120 @default.
• W2017007926 cites W4210743996 @default.
• W2017007926 doi "https://doi.org/10.1016/j.ijsu.2009.10.010" @default.
• W2017007926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19883802" @default.
• W2017007926 hasPublicationYear "2010" @default.
• W2017007926 type Work @default.
• W2017007926 sameAs 2017007926 @default.
• W2017007926 citedByCount "4" @default.
• W2017007926 countsByYear W20170079262013 @default.
• W2017007926 countsByYear W20170079262014 @default.
• W2017007926 countsByYear W20170079262017 @default.
• W2017007926 crossrefType "journal-article" @default.
• W2017007926 hasAuthorship W2017007926A5016764433 @default.
• W2017007926 hasAuthorship W2017007926A5025044096 @default.
• W2017007926 hasAuthorship W2017007926A5052291824 @default.
• W2017007926 hasAuthorship W2017007926A5067451949 @default.
• W2017007926 hasBestOaLocation W20170079261 @default.
• W2017007926 hasConcept C126322002 @default.
• W2017007926 hasConcept C141071460 @default.
• W2017007926 hasConcept C2776301958 @default.
• W2017007926 hasConcept C2778080469 @default.
• W2017007926 hasConcept C2779161974 @default.
• W2017007926 hasConcept C2780014101 @default.
• W2017007926 hasConcept C71924100 @default.
• W2017007926 hasConceptScore W2017007926C126322002 @default.
• W2017007926 hasConceptScore W2017007926C141071460 @default.
• W2017007926 hasConceptScore W2017007926C2776301958 @default.
• W2017007926 hasConceptScore W2017007926C2778080469 @default.
• W2017007926 hasConceptScore W2017007926C2779161974 @default.
• W2017007926 hasConceptScore W2017007926C2780014101 @default.
• W2017007926 hasConceptScore W2017007926C71924100 @default.
• W2017007926 hasIssue "1" @default.
• W2017007926 hasLocation W20170079261 @default.
• W2017007926 hasLocation W20170079262 @default.
• W2017007926 hasOpenAccess W2017007926 @default.
• W2017007926 hasPrimaryLocation W20170079261 @default.
• W2017007926 hasRelatedWork W1995900004 @default.
• W2017007926 hasRelatedWork W2010333783 @default.
• W2017007926 hasRelatedWork W2048402298 @default.
• W2017007926 hasRelatedWork W2111947972 @default.
• W2017007926 hasRelatedWork W2287908101 @default.
• W2017007926 hasRelatedWork W2464515962 @default.
• W2017007926 hasRelatedWork W2607872642 @default.
• W2017007926 hasRelatedWork W2771076376 @default.
• W2017007926 hasRelatedWork W3118595014 @default.
• W2017007926 hasRelatedWork W4235100993 @default.
• W2017007926 hasVolume "8" @default.
• W2017007926 isParatext "false" @default.
• W2017007926 isRetracted "false" @default.
• W2017007926 magId "2017007926" @default.
• W2017007926 workType "article" @default.