FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017009049> ?p ?o ?g. }

• W2017009049 endingPage "174" @default.
• W2017009049 startingPage "164" @default.
• W2017009049 abstract "Using a one-dimensional rapid imaging technique, we have found that injection of lanthanide chelates such as Gd(DTPA)2− leads to a significant decrease (50%) in rat brain signal intensity at 1.45 T using T2-weighted pulse sequences; however, no effect of comparable size is observed with T1-weighted pulse sequences. The transient effect and its kinetics were followed with a temporal resolution of between 1 and 8 s. Experiments with different lanthanide chelates show that the observed decrease in signal intensity correlates with the magnetic moment of each agent but not with their longitudinal relaxivity. Three-dimensional chemical-shift resolved experiments demonstrate significant line broadening in brain during infusion with Dy(DTPA)2− Our results show that the cause of this effect is the difference in susceptibility between the capillaries, containing the contrast agent, and the surrounding tissue. As a result of these susceptibility differences, field gradients are produced in the tissue and diffusion of water through these gradients leads to a loss of spin phase coherence and thus a decrease in signal intensity. We propose this as a new type of contrast agent mechanism in NMR. The effect and its kinetics are likely to be related to important physiological parameters such as cerebral blood volume and cerebral blood flow, and do not depend on a breakdown of the blood-brain barrier as do conventional contrast agent techniques. © 1988 Academic Press, Inc." @default.
• W2017009049 created "2016-06-24" @default.
• W2017009049 creator A5003473906 @default.
• W2017009049 creator A5004268054 @default.
• W2017009049 creator A5020270555 @default.
• W2017009049 creator A5027182724 @default.
• W2017009049 creator A5041500174 @default.
• W2017009049 creator A5073290912 @default.
• W2017009049 creator A5074699335 @default.
• W2017009049 creator A5074726900 @default.
• W2017009049 creator A5083240509 @default.
• W2017009049 date "1988-02-01" @default.
• W2017009049 modified "2023-09-26" @default.
• W2017009049 title "Dynamic imaging with lanthanide chelates in normal brain: Contrast due to magnetic susceptibility effects" @default.
• W2017009049 cites W1965006837 @default.
• W2017009049 cites W1968407046 @default.
• W2017009049 cites W1969115045 @default.
• W2017009049 cites W1980086703 @default.
• W2017009049 cites W1981596913 @default.
• W2017009049 cites W1986325093 @default.
• W2017009049 cites W1997017061 @default.
• W2017009049 cites W2008194777 @default.
• W2017009049 cites W2018396383 @default.
• W2017009049 cites W2059864970 @default.
• W2017009049 cites W2060591755 @default.
• W2017009049 cites W2066972542 @default.
• W2017009049 cites W2077756726 @default.
• W2017009049 cites W2079917976 @default.
• W2017009049 cites W2082218291 @default.
• W2017009049 cites W2087595625 @default.
• W2017009049 cites W2134814559 @default.
• W2017009049 cites W2146941741 @default.
• W2017009049 cites W2950321054 @default.
• W2017009049 cites W4254297188 @default.
• W2017009049 doi "https://doi.org/10.1002/mrm.1910060205" @default.
• W2017009049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3367774" @default.
• W2017009049 hasPublicationYear "1988" @default.
• W2017009049 type Work @default.
• W2017009049 sameAs 2017009049 @default.
• W2017009049 citedByCount "668" @default.
• W2017009049 countsByYear W20170090492012 @default.
• W2017009049 countsByYear W20170090492013 @default.
• W2017009049 countsByYear W20170090492014 @default.
• W2017009049 countsByYear W20170090492015 @default.
• W2017009049 countsByYear W20170090492016 @default.
• W2017009049 countsByYear W20170090492017 @default.
• W2017009049 countsByYear W20170090492018 @default.
• W2017009049 countsByYear W20170090492019 @default.
• W2017009049 countsByYear W20170090492020 @default.
• W2017009049 countsByYear W20170090492021 @default.
• W2017009049 countsByYear W20170090492022 @default.
• W2017009049 countsByYear W20170090492023 @default.
• W2017009049 crossrefType "journal-article" @default.
• W2017009049 hasAuthorship W2017009049A5003473906 @default.
• W2017009049 hasAuthorship W2017009049A5004268054 @default.
• W2017009049 hasAuthorship W2017009049A5020270555 @default.
• W2017009049 hasAuthorship W2017009049A5027182724 @default.
• W2017009049 hasAuthorship W2017009049A5041500174 @default.
• W2017009049 hasAuthorship W2017009049A5073290912 @default.
• W2017009049 hasAuthorship W2017009049A5074699335 @default.
• W2017009049 hasAuthorship W2017009049A5074726900 @default.
• W2017009049 hasAuthorship W2017009049A5083240509 @default.
• W2017009049 hasConcept C120665830 @default.
• W2017009049 hasConcept C121332964 @default.
• W2017009049 hasConcept C126838900 @default.
• W2017009049 hasConcept C143409427 @default.
• W2017009049 hasConcept C145148216 @default.
• W2017009049 hasConcept C148898269 @default.
• W2017009049 hasConcept C157767197 @default.
• W2017009049 hasConcept C164705383 @default.
• W2017009049 hasConcept C178790620 @default.
• W2017009049 hasConcept C182155053 @default.
• W2017009049 hasConcept C185592680 @default.
• W2017009049 hasConcept C197404232 @default.
• W2017009049 hasConcept C201770740 @default.
• W2017009049 hasConcept C2776502983 @default.
• W2017009049 hasConcept C2780167933 @default.
• W2017009049 hasConcept C46141821 @default.
• W2017009049 hasConcept C62520636 @default.
• W2017009049 hasConcept C71924100 @default.
• W2017009049 hasConcept C93038891 @default.
• W2017009049 hasConcept C94915269 @default.
• W2017009049 hasConceptScore W2017009049C120665830 @default.
• W2017009049 hasConceptScore W2017009049C121332964 @default.
• W2017009049 hasConceptScore W2017009049C126838900 @default.
• W2017009049 hasConceptScore W2017009049C143409427 @default.
• W2017009049 hasConceptScore W2017009049C145148216 @default.
• W2017009049 hasConceptScore W2017009049C148898269 @default.
• W2017009049 hasConceptScore W2017009049C157767197 @default.
• W2017009049 hasConceptScore W2017009049C164705383 @default.
• W2017009049 hasConceptScore W2017009049C178790620 @default.
• W2017009049 hasConceptScore W2017009049C182155053 @default.
• W2017009049 hasConceptScore W2017009049C185592680 @default.
• W2017009049 hasConceptScore W2017009049C197404232 @default.
• W2017009049 hasConceptScore W2017009049C201770740 @default.
• W2017009049 hasConceptScore W2017009049C2776502983 @default.
• W2017009049 hasConceptScore W2017009049C2780167933 @default.
• W2017009049 hasConceptScore W2017009049C46141821 @default.

• next