Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017010259> ?p ?o ?g. }
- W2017010259 endingPage "139" @default.
- W2017010259 startingPage "124" @default.
- W2017010259 abstract "BST-2 restricts MMTV replication, but once infection has established, MMTV modulates BST-2 levels. MMTV-directed BST-2 modulation is tissue-specific and dependent on infection and neoplastic transformation status of cells. In the lymphoid compartment of infected mice, BST-2 expression is first upregulated and then significantly downregulated regardless of absence or presence of mammary tumors. However, in mammary gland tissues, upregulation of BST-2 expression is dependent on the presence of mammary tumors and tumor tissues themselves have high BST-2 levels. Elevated BST-2 expression in these tissues is not attributable to IFN since levels of IFNα and IFNγ negatively correlate with BST-2. Importantly, soluble factors released by tumor cells suppress IFNα and IFNγ but induce BST-2. These data suggest that overexpression of BST-2 in carcinoma tissues could not be attributed to IFNs but to a yet to be determined factor that upregulates BST-2 once oncogenesis is initiated." @default.
- W2017010259 created "2016-06-24" @default.
- W2017010259 creator A5028413203 @default.
- W2017010259 creator A5063102539 @default.
- W2017010259 creator A5068644383 @default.
- W2017010259 creator A5087556481 @default.
- W2017010259 date "2013-09-01" @default.
- W2017010259 modified "2023-10-02" @default.
- W2017010259 title "BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer" @default.
- W2017010259 cites W1501785654 @default.
- W2017010259 cites W1516195543 @default.
- W2017010259 cites W1594922586 @default.
- W2017010259 cites W1649707949 @default.
- W2017010259 cites W1735408039 @default.
- W2017010259 cites W1794594157 @default.
- W2017010259 cites W1965865401 @default.
- W2017010259 cites W1967617815 @default.
- W2017010259 cites W1968918264 @default.
- W2017010259 cites W1970751001 @default.
- W2017010259 cites W1971940383 @default.
- W2017010259 cites W1976421539 @default.
- W2017010259 cites W1981516870 @default.
- W2017010259 cites W1982906893 @default.
- W2017010259 cites W1992589524 @default.
- W2017010259 cites W1995360688 @default.
- W2017010259 cites W1996431119 @default.
- W2017010259 cites W1996798386 @default.
- W2017010259 cites W1997433322 @default.
- W2017010259 cites W1999295228 @default.
- W2017010259 cites W1999549536 @default.
- W2017010259 cites W2006749087 @default.
- W2017010259 cites W2006778528 @default.
- W2017010259 cites W2006982410 @default.
- W2017010259 cites W2010458160 @default.
- W2017010259 cites W2016913504 @default.
- W2017010259 cites W2025203479 @default.
- W2017010259 cites W2027012174 @default.
- W2017010259 cites W2029451367 @default.
- W2017010259 cites W2032769992 @default.
- W2017010259 cites W2035040442 @default.
- W2017010259 cites W2039697834 @default.
- W2017010259 cites W2040730301 @default.
- W2017010259 cites W2045098741 @default.
- W2017010259 cites W2045637897 @default.
- W2017010259 cites W2045877830 @default.
- W2017010259 cites W2057487057 @default.
- W2017010259 cites W2058924268 @default.
- W2017010259 cites W2063187123 @default.
- W2017010259 cites W2065027173 @default.
- W2017010259 cites W2066528650 @default.
- W2017010259 cites W2067237117 @default.
- W2017010259 cites W2071138210 @default.
- W2017010259 cites W2071428576 @default.
- W2017010259 cites W2075529734 @default.
- W2017010259 cites W2079754527 @default.
- W2017010259 cites W2086648451 @default.
- W2017010259 cites W2093115609 @default.
- W2017010259 cites W2096200786 @default.
- W2017010259 cites W2099917742 @default.
- W2017010259 cites W2103066559 @default.
- W2017010259 cites W2105264711 @default.
- W2017010259 cites W2110114546 @default.
- W2017010259 cites W2113130193 @default.
- W2017010259 cites W2113280225 @default.
- W2017010259 cites W2114444869 @default.
- W2017010259 cites W2121632263 @default.
- W2017010259 cites W2123225304 @default.
- W2017010259 cites W2123563900 @default.
- W2017010259 cites W2125707557 @default.
- W2017010259 cites W2126794945 @default.
- W2017010259 cites W2129172191 @default.
- W2017010259 cites W2129604624 @default.
- W2017010259 cites W2132948186 @default.
- W2017010259 cites W2135922772 @default.
- W2017010259 cites W2137622537 @default.
- W2017010259 cites W2139731402 @default.
- W2017010259 cites W2140675472 @default.
- W2017010259 cites W2143039126 @default.
- W2017010259 cites W2143790526 @default.
- W2017010259 cites W2144683339 @default.
- W2017010259 cites W2147114673 @default.
- W2017010259 cites W2151285519 @default.
- W2017010259 cites W2151549305 @default.
- W2017010259 cites W2154028353 @default.
- W2017010259 cites W2159265075 @default.
- W2017010259 cites W2161142071 @default.
- W2017010259 cites W2161190844 @default.
- W2017010259 cites W2162168594 @default.
- W2017010259 cites W2163965347 @default.
- W2017010259 cites W2164139183 @default.
- W2017010259 cites W2168326171 @default.
- W2017010259 cites W2168606329 @default.
- W2017010259 cites W2168900833 @default.
- W2017010259 doi "https://doi.org/10.1016/j.virol.2013.05.042" @default.
- W2017010259 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4026021" @default.
- W2017010259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23806386" @default.
- W2017010259 hasPublicationYear "2013" @default.
- W2017010259 type Work @default.