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• W2017016916 endingPage "234" @default.
• W2017016916 startingPage "200" @default.
• W2017016916 abstract "It is estimated that one-third of the world's population is infected with tubercle bacillus and the problem of tuberculosis (TB) has been intensified due to HIV pandemic providing a large reservoir of highly susceptible individuals. Since no anti-TB drugs have been introduced in past 30 years, there is an urgent need to search for and develop new, effective and affordable anti-TB drugs. In this scenario, the plant kingdom with enormous chemical diversity may be looked as an important source of new anti-TB agents. Of 17,500 higher plant species occurring in India only about 365 species have been evaluated so far for antimycobacterial activity. The present review article describes the 255 (70% of 365) plant species from a wide range of families that have shown antimycobacterial activity. The species are enumerated in table format describing plant species and family, plant part used, type of extract and in vitro activity (MIC value), information on active compounds, if any, and uses in the ethnomedicine and Ayurveda. Interestingly, most of the plant species have shown strong positive ethnopharmacological correlation with the traditional knowledge. In addition, the recent in vitro screening methods for antimycobacterial activity are also described in brief. An attempt has been made to highlight the promising plant species for further investigation as leads for drug development." @default.
• W2017016916 created "2016-06-24" @default.
• W2017016916 creator A5028149131 @default.
• W2017016916 creator A5061876982 @default.
• W2017016916 creator A5066582203 @default.
• W2017016916 date "2007-03-01" @default.
• W2017016916 modified "2023-10-14" @default.
• W2017016916 title "Indian medicinal plants as a source of antimycobacterial agents" @default.
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• W2017016916 doi "https://doi.org/10.1016/j.jep.2006.12.031" @default.
• W2017016916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17276637" @default.

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