Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017018437> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2017018437 endingPage "132" @default.
- W2017018437 startingPage "121" @default.
- W2017018437 abstract "Canine parvovirus (CPV) emerged in 1978 an a new pathogen of dogs, which spread around the world and now appears endemic in the domesticated and wild dog populations in all countries. CPV is over 98% identical in DNA sequence to viruses which had been known for many years in cats, mink and raccoons, and genetic analysis has revealed that the differences in canine host range are determined by a small number of changes in the capsid protein gene. Comparison of the atomic structures of the CPV and FPV capsids shows that the changes affecting host range and virus-specific antigenic sites are exposed on the capsid surface in three different positions within a raised region at the threefold axis of symmetry, which is also the site of major antigenic determinants on the capsid. Three types of CPV have been defined by antigenic analysis with monoclonal antibodies. The original CPV strain (called CPV type-2) was only present in nature for a few years, and by 1981 it had been largely replaced in nature by a variant of CPV (CPV type 2a), which in turn replaced between 1984 and 1990 by a further variant (CPV type-2b). Those viruses differed by less than 0.2% of their genome sequences, but in each case the replacement apparently occurred on a global scale. The true ancestry of CPV is not clear, but the apparent emergence of the new types of CPV and its subsequent evolution suggest that this is a useful model for the emergence of new viruses with extended host ranges and their continuing adaptation." @default.
- W2017018437 created "2016-06-24" @default.
- W2017018437 creator A5050514884 @default.
- W2017018437 date "1994-04-01" @default.
- W2017018437 modified "2023-09-23" @default.
- W2017018437 title "The emergence and evolution of canine parvovirus—an example of recent host range mutation" @default.
- W2017018437 doi "https://doi.org/10.1006/smvy.1994.1013" @default.
- W2017018437 hasPublicationYear "1994" @default.
- W2017018437 type Work @default.
- W2017018437 sameAs 2017018437 @default.
- W2017018437 citedByCount "33" @default.
- W2017018437 countsByYear W20170184372013 @default.
- W2017018437 countsByYear W20170184372014 @default.
- W2017018437 countsByYear W20170184372015 @default.
- W2017018437 countsByYear W20170184372016 @default.
- W2017018437 countsByYear W20170184372021 @default.
- W2017018437 countsByYear W20170184372023 @default.
- W2017018437 crossrefType "journal-article" @default.
- W2017018437 hasAuthorship W2017018437A5050514884 @default.
- W2017018437 hasBestOaLocation W20170184371 @default.
- W2017018437 hasConcept C104317684 @default.
- W2017018437 hasConcept C126831891 @default.
- W2017018437 hasConcept C141231307 @default.
- W2017018437 hasConcept C159047783 @default.
- W2017018437 hasConcept C18903297 @default.
- W2017018437 hasConcept C202878990 @default.
- W2017018437 hasConcept C2522874641 @default.
- W2017018437 hasConcept C2779630601 @default.
- W2017018437 hasConcept C2780339557 @default.
- W2017018437 hasConcept C2780754187 @default.
- W2017018437 hasConcept C54355233 @default.
- W2017018437 hasConcept C86803240 @default.
- W2017018437 hasConceptScore W2017018437C104317684 @default.
- W2017018437 hasConceptScore W2017018437C126831891 @default.
- W2017018437 hasConceptScore W2017018437C141231307 @default.
- W2017018437 hasConceptScore W2017018437C159047783 @default.
- W2017018437 hasConceptScore W2017018437C18903297 @default.
- W2017018437 hasConceptScore W2017018437C202878990 @default.
- W2017018437 hasConceptScore W2017018437C2522874641 @default.
- W2017018437 hasConceptScore W2017018437C2779630601 @default.
- W2017018437 hasConceptScore W2017018437C2780339557 @default.
- W2017018437 hasConceptScore W2017018437C2780754187 @default.
- W2017018437 hasConceptScore W2017018437C54355233 @default.
- W2017018437 hasConceptScore W2017018437C86803240 @default.
- W2017018437 hasIssue "2" @default.
- W2017018437 hasLocation W20170184371 @default.
- W2017018437 hasOpenAccess W2017018437 @default.
- W2017018437 hasPrimaryLocation W20170184371 @default.
- W2017018437 hasRelatedWork W1998047447 @default.
- W2017018437 hasRelatedWork W2017296038 @default.
- W2017018437 hasRelatedWork W2028327194 @default.
- W2017018437 hasRelatedWork W2035984300 @default.
- W2017018437 hasRelatedWork W2039425087 @default.
- W2017018437 hasRelatedWork W2163643748 @default.
- W2017018437 hasRelatedWork W2325238661 @default.
- W2017018437 hasRelatedWork W2342106670 @default.
- W2017018437 hasRelatedWork W2392839378 @default.
- W2017018437 hasRelatedWork W30612849 @default.
- W2017018437 hasVolume "5" @default.
- W2017018437 isParatext "false" @default.
- W2017018437 isRetracted "false" @default.
- W2017018437 magId "2017018437" @default.
- W2017018437 workType "article" @default.