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- W2017024149 abstract "Rat hepatocytes were maintained in a serum-free, hormonally defined medium supplemented with 50-500 microM albumin-bound 20:1 (n-9) vs 20:4 (n-6). The induction of fatty acid synthase mRNA by a mix of insulin/dexamethasone/T3 was inhibited in a dose dependent fashion by 20:4 (n-6). The abundance of beta-actin mRNA was not suppressed by 20:4 (n-6). The expression of fatty acid synthase was actually stimulated 2-fold by 20:1 (n-9). It would appear that the in vivo inhibition of fatty acid synthase gene expression by dietary polyunsaturated fatty acids is a specific hepatocelluar event." @default.
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- W2017024149 date "1991-06-01" @default.
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- W2017024149 title "Arachidonic acid suppression of fatty acid synthase gene expression in cultured rat hepatocytes" @default.
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- W2017024149 doi "https://doi.org/10.1016/0006-291x(91)90645-n" @default.
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