Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017051726> ?p ?o ?g. }
- W2017051726 endingPage "299" @default.
- W2017051726 startingPage "295" @default.
- W2017051726 abstract "Mounting an appropriate immune response depends on the careful regulation of lymphocyte activation. To this end, lymphocytes require two independent signals to become fully activated. The first, an antigen-specific signal is sent via the unique antigen receptor: T cell receptor (TCR) on T cells or surface Ig on B cells. The second signal, termed costimulation, is independent of the antigen receptor and is critical to allow full activation, sustain cell proliferation, prevent anergy and/or apoptosis, induce differentiation to effector and memory status, and allow cell-cell cooperation. Costimulation is in turn regulated by the expression of inhibitory receptors upon lymphocyte activation. Here we will consider the growing list of costimulatory and inhibitory molecules, with emphasis on signaling events they initiate. Potentially complex patterns of regulation implied by the variety of receptor/ligand pairs and their differential expression patterns will also be discussed." @default.
- W2017051726 created "2016-06-24" @default.
- W2017051726 creator A5058652755 @default.
- W2017051726 creator A5088551754 @default.
- W2017051726 date "2002-02-01" @default.
- W2017051726 modified "2023-10-16" @default.
- W2017051726 title "Activation and inhibition of lymphocytes by costimulation" @default.
- W2017051726 cites W118130514 @default.
- W2017051726 cites W1481604295 @default.
- W2017051726 cites W1482598749 @default.
- W2017051726 cites W1513014113 @default.
- W2017051726 cites W1513178664 @default.
- W2017051726 cites W1537465465 @default.
- W2017051726 cites W1546040866 @default.
- W2017051726 cites W1550965773 @default.
- W2017051726 cites W1564765245 @default.
- W2017051726 cites W1596079370 @default.
- W2017051726 cites W1626388077 @default.
- W2017051726 cites W1647115901 @default.
- W2017051726 cites W1661441964 @default.
- W2017051726 cites W1667545291 @default.
- W2017051726 cites W1807189640 @default.
- W2017051726 cites W1898621392 @default.
- W2017051726 cites W1927121266 @default.
- W2017051726 cites W1968546256 @default.
- W2017051726 cites W1978373343 @default.
- W2017051726 cites W1978391103 @default.
- W2017051726 cites W2000517438 @default.
- W2017051726 cites W2006554521 @default.
- W2017051726 cites W2008065206 @default.
- W2017051726 cites W2008704486 @default.
- W2017051726 cites W2012972418 @default.
- W2017051726 cites W2020991100 @default.
- W2017051726 cites W2022697474 @default.
- W2017051726 cites W2024367381 @default.
- W2017051726 cites W2026893575 @default.
- W2017051726 cites W2027533965 @default.
- W2017051726 cites W2038638713 @default.
- W2017051726 cites W2041980736 @default.
- W2017051726 cites W2042250320 @default.
- W2017051726 cites W2052077392 @default.
- W2017051726 cites W2056535502 @default.
- W2017051726 cites W2065633276 @default.
- W2017051726 cites W2068817531 @default.
- W2017051726 cites W2070551264 @default.
- W2017051726 cites W2075728929 @default.
- W2017051726 cites W2088237595 @default.
- W2017051726 cites W2098658552 @default.
- W2017051726 cites W2103002807 @default.
- W2017051726 cites W2107752337 @default.
- W2017051726 cites W2112941906 @default.
- W2017051726 cites W2114256900 @default.
- W2017051726 cites W2118471749 @default.
- W2017051726 cites W2121934915 @default.
- W2017051726 cites W2133866843 @default.
- W2017051726 cites W2134372981 @default.
- W2017051726 cites W2136866940 @default.
- W2017051726 cites W2140066663 @default.
- W2017051726 cites W2141427930 @default.
- W2017051726 cites W2145871366 @default.
- W2017051726 cites W2152812674 @default.
- W2017051726 cites W2163668561 @default.
- W2017051726 cites W2414696663 @default.
- W2017051726 cites W2560367415 @default.
- W2017051726 cites W2572174216 @default.
- W2017051726 cites W4293168410 @default.
- W2017051726 doi "https://doi.org/10.1172/jci14941" @default.
- W2017051726 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/150864" @default.
- W2017051726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11827987" @default.
- W2017051726 hasPublicationYear "2002" @default.
- W2017051726 type Work @default.
- W2017051726 sameAs 2017051726 @default.
- W2017051726 citedByCount "137" @default.
- W2017051726 countsByYear W20170517262012 @default.
- W2017051726 countsByYear W20170517262013 @default.
- W2017051726 countsByYear W20170517262014 @default.
- W2017051726 countsByYear W20170517262015 @default.
- W2017051726 countsByYear W20170517262016 @default.
- W2017051726 countsByYear W20170517262017 @default.
- W2017051726 countsByYear W20170517262018 @default.
- W2017051726 countsByYear W20170517262019 @default.
- W2017051726 countsByYear W20170517262020 @default.
- W2017051726 countsByYear W20170517262021 @default.
- W2017051726 countsByYear W20170517262022 @default.
- W2017051726 countsByYear W20170517262023 @default.
- W2017051726 crossrefType "journal-article" @default.
- W2017051726 hasAuthorship W2017051726A5058652755 @default.
- W2017051726 hasAuthorship W2017051726A5088551754 @default.
- W2017051726 hasBestOaLocation W20170517261 @default.
- W2017051726 hasConcept C185592680 @default.
- W2017051726 hasConcept C203014093 @default.
- W2017051726 hasConcept C2776090121 @default.
- W2017051726 hasConcept C3017602531 @default.
- W2017051726 hasConcept C71924100 @default.
- W2017051726 hasConcept C86803240 @default.
- W2017051726 hasConcept C8891405 @default.
- W2017051726 hasConcept C95444343 @default.
- W2017051726 hasConceptScore W2017051726C185592680 @default.