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- W2017053068 abstract "<b>Objectives:</b> To develop subjective (visual) and objective (morphometric) rating scales for the classification of MRI in infants who had microcephaly with a simplified gyral pattern (MSGP) and to validate the first by the latter. <b>Methods:</b> We compared the MRI of 12 patients with MSGP and of 5 term-born control infants. Visual rating and morphometric analysis was performed for gyration and associated brain abnormalities of basal ganglia, lateral ventricles, pons, cerebellum, and corpus callosum. <b>Results:</b> Gyral pattern was rated reliably as normal in the control infants, simplified in 6 patients, and severely simplified in the other 6 patients. Associated brain abnormalities were reported in 10 of 12 patients. Visual rating correlated well with the morphometric measures. <b>Conclusions:</b> Our visual rating scale for a simplified gyral pattern proved to be sensitive and reliable. Associated brain abnormalities are frequent, which underlines the need for a consistent scoring in these patients." @default.
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- W2017053068 date "2010-02-01" @default.
- W2017053068 modified "2023-10-17" @default.
- W2017053068 title "Microcephaly with simplified gyral pattern: MRI classification" @default.
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- W2017053068 doi "https://doi.org/10.1212/wnl.0b013e3181ce5d82" @default.
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