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- W2017090534 abstract "An impurity in the initial scale-up batch of PDA-641 was identified and the pathway of its formation was established. The precursor of the impurity was formed by magnesium Meerwein-Ponndorf-Verley-Oppenauer reaction during the Grignard addition step. As a result of the investigation, the level of the impurity could be reduced 6-fold in the subsequent batch." @default.
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- W2017090534 date "1998-10-29" @default.
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- W2017090534 title "Magnesium Meerwein−Ponndorf−Verley−Oppenauer Reaction. The Origin of an Impurity in PDA-641 Batches" @default.
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- W2017090534 doi "https://doi.org/10.1021/op980078o" @default.
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