Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017092085> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2017092085 endingPage "386" @default.
- W2017092085 startingPage "385" @default.
- W2017092085 abstract "The effect of the trivalent cations scandium (Sc3+) and yttrium (Y3+) on the conformation of G-actin was examined using ultraviolet difference and high resolution 1H-NMR spectroscopy. A comparison was made with data obtained previously with the trivalent lanthanide cations (Ln3+). These results indicate that the first and subsequent Y ions (ionic radius 101.9 pm) behave exactly like Ln3+. Sc3+ is a smaller ion (87 pm) than any of the Ln3+. The first Sc3+ binds to a site on actin that is inaccessible to Mg2+, Y3+ and Ln3+. However, the second Sc3+ to bind behaves like an Ln3+. On replacing the native divalent cation (Mg2+), both Y3+ and Sc3+ mobilize the adenine ring of ATP bound to actin, thus exposing underlying residues to the solvent. When Y3+ and Sc3+ saturate their binding sites on actin, and when the ionic strength is raised to 0.1 M with KCI at pH 6.9, the actin aggregates. Y3+ binds to actin with a ratio of 6 : 1 and induces the aggregation of actin into crystalline actin tubes, whilstSc3+ Sc3+binds with a ratio of 8 : 1 and induces amorphous actin aggregates. These results are consistent with the suggestion that actin tubes are induced by trivalent cations, principally on the basis of their binding stoichiometry, which in turn is determined by ionic radius." @default.
- W2017092085 created "2016-06-24" @default.
- W2017092085 creator A5036647535 @default.
- W2017092085 creator A5060730302 @default.
- W2017092085 creator A5062838700 @default.
- W2017092085 date "1980-01-01" @default.
- W2017092085 modified "2023-10-14" @default.
- W2017092085 title "Structural similarities and differences between crystalline actin aggregates formed by the lanthanide ions" @default.
- W2017092085 cites W1969152345 @default.
- W2017092085 cites W1982532257 @default.
- W2017092085 cites W2027533227 @default.
- W2017092085 cites W2030608500 @default.
- W2017092085 cites W2055384511 @default.
- W2017092085 cites W2093830604 @default.
- W2017092085 doi "https://doi.org/10.1016/0047-7206(80)90058-8" @default.
- W2017092085 hasPublicationYear "1980" @default.
- W2017092085 type Work @default.
- W2017092085 sameAs 2017092085 @default.
- W2017092085 citedByCount "2" @default.
- W2017092085 crossrefType "journal-article" @default.
- W2017092085 hasAuthorship W2017092085A5036647535 @default.
- W2017092085 hasAuthorship W2017092085A5060730302 @default.
- W2017092085 hasAuthorship W2017092085A5062838700 @default.
- W2017092085 hasConcept C125705527 @default.
- W2017092085 hasConcept C145148216 @default.
- W2017092085 hasConcept C178790620 @default.
- W2017092085 hasConcept C179104552 @default.
- W2017092085 hasConcept C185592680 @default.
- W2017092085 hasConcept C201770740 @default.
- W2017092085 hasConcept C54998646 @default.
- W2017092085 hasConcept C55493867 @default.
- W2017092085 hasConcept C74884574 @default.
- W2017092085 hasConcept C8010536 @default.
- W2017092085 hasConceptScore W2017092085C125705527 @default.
- W2017092085 hasConceptScore W2017092085C145148216 @default.
- W2017092085 hasConceptScore W2017092085C178790620 @default.
- W2017092085 hasConceptScore W2017092085C179104552 @default.
- W2017092085 hasConceptScore W2017092085C185592680 @default.
- W2017092085 hasConceptScore W2017092085C201770740 @default.
- W2017092085 hasConceptScore W2017092085C54998646 @default.
- W2017092085 hasConceptScore W2017092085C55493867 @default.
- W2017092085 hasConceptScore W2017092085C74884574 @default.
- W2017092085 hasConceptScore W2017092085C8010536 @default.
- W2017092085 hasIssue "3-4" @default.
- W2017092085 hasLocation W20170920851 @default.
- W2017092085 hasOpenAccess W2017092085 @default.
- W2017092085 hasPrimaryLocation W20170920851 @default.
- W2017092085 hasRelatedWork W1963553900 @default.
- W2017092085 hasRelatedWork W1967898554 @default.
- W2017092085 hasRelatedWork W1969152345 @default.
- W2017092085 hasRelatedWork W1973418831 @default.
- W2017092085 hasRelatedWork W1991778197 @default.
- W2017092085 hasRelatedWork W2328839979 @default.
- W2017092085 hasRelatedWork W2952000579 @default.
- W2017092085 hasRelatedWork W3003223359 @default.
- W2017092085 hasRelatedWork W3193098389 @default.
- W2017092085 hasRelatedWork W2951482124 @default.
- W2017092085 hasVolume "11" @default.
- W2017092085 isParatext "false" @default.
- W2017092085 isRetracted "false" @default.
- W2017092085 magId "2017092085" @default.
- W2017092085 workType "article" @default.