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• W2017093896 abstract "In contrast to many isotropic finite-element (FE) models of the femur in literature, it was the object of our study to develop an orthotropic FE model femur to realistically simulate three-dimensional bone remodelling.The three-dimensional geometry of the proximal femur was reconstructed by CT scans of a pair of cadaveric femurs at equal distances of 2mm. These three-dimensional CT models were implemented into an FE simulation tool. Well-known density-determined bony material properties (Young's modulus; Poisson's ratio; ultimate strength in pressure, tension and torsion; shear modulus) were assigned to each FE of the same CT-density-characterized volumetric group. In order to fix the principal directions of stiffness in FE areas with the same density characterization, the cadaveric femurs were cut in 2mm slices in frontal (left femur) and sagittal plane (right femur). Each femoral slice was scanned into a computer-based image processing system. On these images, the principal directions of stiffness of cancellous and cortical bone were determined manually using the orientation of the trabecular structures and the Haversian system. Finally, these geometric data were matched with the CT-density characterized three-dimensional femur model. In addition, the time and density-dependent adaptive behaviour of bone remodelling was taken into account by implementation of Carter's criterion.In the constructed model femur, each FE is characterized by the principal directions of the stiffness and the CT-density-determined material properties of cortical and cancellous bone. Thus, on the basis of anatomic data a three-dimensional FE simulation reference model of the proximal femur was realized considering orthotropic conditions of bone behaviour.With the orthotropic model femur, the fundamental basis has been formed to realize realistic simulations of the dynamical processes of bone remodelling under different loading conditions or operative procedures (osteotomies, total hip replacements, etc)." @default.
• W2017093896 created "2016-06-24" @default.
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• W2017093896 date "2003-02-01" @default.
• W2017093896 modified "2023-10-16" @default.
• W2017093896 title "Concept and development of an orthotropic FE model of the proximal femur" @default.
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• W2017093896 doi "https://doi.org/10.1016/s0021-9290(02)00309-3" @default.
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