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- W2017100085 abstract "TenA catalyzes the hydrolysis of 4-amino-5-aminomethyl-2-methylpyrimidine and participates in the salvage of base-degraded thiamin. Here, we describe mutagenesis of the active site of TenA guided by structures of the enzyme complexed to a substrate analog and to the product. Catalytic roles for each of the active site residues are identified and a mechanism for the reaction is described." @default.
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- W2017100085 date "2008-02-01" @default.
- W2017100085 modified "2023-09-25" @default.
- W2017100085 title "Mutagenesis studies on TenA: A thiamin salvage enzyme from Bacillus subtilis" @default.
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- W2017100085 doi "https://doi.org/10.1016/j.bioorg.2007.10.005" @default.
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