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• W2017101734 abstract "The rate-limiting step in the absorption of poorly water-soluble drugs is often the dissolution process of these compounds. Surface-active agents influence the dissolution process by wetting and solubilizing. In order to study the effect of solubilization, a rotating-disk apparatus was used with griseofulvin as a model drug substance and sodium dodecylsulphate (SDS) as a model surfactant. The dissolution kinetics of griseofulvin in SDS solutions could adequately be described by the convective-diffusion model and the phase-separation model for micellar systems. The calculated micellar diffusion coefficient of SDS was in close agreement with values reported in the literature." @default.
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• W2017101734 date "1987-09-01" @default.
• W2017101734 modified "2023-10-18" @default.
• W2017101734 title "Dissolution Kinetics of Griseofulvin in Sodium Dodecylsulphate Solutions" @default.
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• W2017101734 doi "https://doi.org/10.1002/jps.2600760909" @default.
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