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- W2017101814 abstract "Previously it was found that during the loss of postural support induced by combined administration of haloperidol and morphine, rats became markedly hypothermic. The present work was a more detailed study of this hypothermia. Morphine alone (20 mg/kg) produced a slight hyperthermia (1 degrees C) in female rats and no effect in males. Haloperidol alone (5 mg/kg) elicited a hypothermia of about 3 degrees C in females and no effect in males. The combination of both elicited a greater decrease of temperature (about 5 degrees C) in female rats and, unexpectedly, a decrease of 3 degrees C in males. According to these data, increased endorphinic activity with a concomitant decrease in dopamine in some unidentified regions of the central nervous system causes hypothermia." @default.
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- W2017101814 date "1987-05-01" @default.
- W2017101814 modified "2023-09-24" @default.
- W2017101814 title "Sex differences in the effects of haloperidol, morphine, and their combination on colonic temperature in rats" @default.
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- W2017101814 doi "https://doi.org/10.1016/0014-4886(87)90055-0" @default.
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