FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017103595> ?p ?o ?g. }

• W2017103595 endingPage "74" @default.
• W2017103595 startingPage "60" @default.
• W2017103595 abstract "Protocatechuate 3,4-dioxygenase (EC 1.13.11.3) from Pseudomonas aeruginosa catalyzes the cleavage of 3,4-dihydroxybenzoate (protocatechuate) into β-carboxy-cis,cis-muconate. The inhibition constants, Ki, of a series of substrate analogues were measured in order to assess the relative importance of the various functional groups on the substrate. Though important for binding, the carboxylate group is not essential for activity. Compounds with para hydroxy groups are better inhibitors than their meta isomers. Our studies of the enzyme inhibitor complexes indicate that the 4-OH group of the substrate binds to the active-site iron. Taken together, Mössbauer, EPR, and kinetic data suggest a mechanism where substrate reaction with oxygen is preceded by metal activation of substrate." @default.
• W2017103595 created "2016-06-24" @default.
• W2017103595 creator A5019917073 @default.
• W2017103595 creator A5035116318 @default.
• W2017103595 creator A5058130714 @default.
• W2017103595 creator A5080592111 @default.
• W2017103595 date "1977-11-01" @default.
• W2017103595 modified "2023-10-03" @default.
• W2017103595 title "Protocatechuate 3,4-dioxygenase" @default.
• W2017103595 cites W1588380766 @default.
• W2017103595 cites W1628593931 @default.
• W2017103595 cites W1986596383 @default.
• W2017103595 cites W1995655158 @default.
• W2017103595 cites W2046695087 @default.
• W2017103595 cites W2046701511 @default.
• W2017103595 cites W2071371827 @default.
• W2017103595 cites W2086214868 @default.
• W2017103595 cites W2124011825 @default.
• W2017103595 cites W2330050631 @default.
• W2017103595 cites W3126250842 @default.
• W2017103595 cites W8205308 @default.
• W2017103595 cites W974572515 @default.
• W2017103595 doi "https://doi.org/10.1016/0005-2744(77)90193-0" @default.
• W2017103595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/199266" @default.
• W2017103595 hasPublicationYear "1977" @default.
• W2017103595 type Work @default.
• W2017103595 sameAs 2017103595 @default.
• W2017103595 citedByCount "122" @default.
• W2017103595 countsByYear W20171035952012 @default.
• W2017103595 countsByYear W20171035952013 @default.
• W2017103595 countsByYear W20171035952014 @default.
• W2017103595 countsByYear W20171035952015 @default.
• W2017103595 countsByYear W20171035952016 @default.
• W2017103595 countsByYear W20171035952017 @default.
• W2017103595 countsByYear W20171035952018 @default.
• W2017103595 countsByYear W20171035952019 @default.
• W2017103595 crossrefType "journal-article" @default.
• W2017103595 hasAuthorship W2017103595A5019917073 @default.
• W2017103595 hasAuthorship W2017103595A5035116318 @default.
• W2017103595 hasAuthorship W2017103595A5058130714 @default.
• W2017103595 hasAuthorship W2017103595A5080592111 @default.
• W2017103595 hasConcept C121332964 @default.
• W2017103595 hasConcept C151730666 @default.
• W2017103595 hasConcept C165474305 @default.
• W2017103595 hasConcept C175156509 @default.
• W2017103595 hasConcept C178790620 @default.
• W2017103595 hasConcept C181199279 @default.
• W2017103595 hasConcept C185592680 @default.
• W2017103595 hasConcept C187961010 @default.
• W2017103595 hasConcept C18903297 @default.
• W2017103595 hasConcept C2776834422 @default.
• W2017103595 hasConcept C2777289219 @default.
• W2017103595 hasConcept C2778074193 @default.
• W2017103595 hasConcept C2994592520 @default.
• W2017103595 hasConcept C41183919 @default.
• W2017103595 hasConcept C43369102 @default.
• W2017103595 hasConcept C46141821 @default.
• W2017103595 hasConcept C540031477 @default.
• W2017103595 hasConcept C544153396 @default.
• W2017103595 hasConcept C55493867 @default.
• W2017103595 hasConcept C71240020 @default.
• W2017103595 hasConcept C86803240 @default.
• W2017103595 hasConceptScore W2017103595C121332964 @default.
• W2017103595 hasConceptScore W2017103595C151730666 @default.
• W2017103595 hasConceptScore W2017103595C165474305 @default.
• W2017103595 hasConceptScore W2017103595C175156509 @default.
• W2017103595 hasConceptScore W2017103595C178790620 @default.
• W2017103595 hasConceptScore W2017103595C181199279 @default.
• W2017103595 hasConceptScore W2017103595C185592680 @default.
• W2017103595 hasConceptScore W2017103595C187961010 @default.
• W2017103595 hasConceptScore W2017103595C18903297 @default.
• W2017103595 hasConceptScore W2017103595C2776834422 @default.
• W2017103595 hasConceptScore W2017103595C2777289219 @default.
• W2017103595 hasConceptScore W2017103595C2778074193 @default.
• W2017103595 hasConceptScore W2017103595C2994592520 @default.
• W2017103595 hasConceptScore W2017103595C41183919 @default.
• W2017103595 hasConceptScore W2017103595C43369102 @default.
• W2017103595 hasConceptScore W2017103595C46141821 @default.
• W2017103595 hasConceptScore W2017103595C540031477 @default.
• W2017103595 hasConceptScore W2017103595C544153396 @default.
• W2017103595 hasConceptScore W2017103595C55493867 @default.
• W2017103595 hasConceptScore W2017103595C71240020 @default.
• W2017103595 hasConceptScore W2017103595C86803240 @default.
• W2017103595 hasIssue "1" @default.
• W2017103595 hasLocation W20171035951 @default.
• W2017103595 hasLocation W20171035952 @default.
• W2017103595 hasOpenAccess W2017103595 @default.
• W2017103595 hasPrimaryLocation W20171035951 @default.
• W2017103595 hasRelatedWork W1757552322 @default.
• W2017103595 hasRelatedWork W2002669403 @default.
• W2017103595 hasRelatedWork W2020980248 @default.
• W2017103595 hasRelatedWork W2037996622 @default.
• W2017103595 hasRelatedWork W2038069682 @default.
• W2017103595 hasRelatedWork W2153017746 @default.
• W2017103595 hasRelatedWork W2309960393 @default.
• W2017103595 hasRelatedWork W2408748231 @default.
• W2017103595 hasRelatedWork W2484500535 @default.
• W2017103595 hasRelatedWork W4384616363 @default.

• next