Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017106076> ?p ?o ?g. }
- W2017106076 endingPage "400" @default.
- W2017106076 startingPage "393" @default.
- W2017106076 abstract "This study reports the release properties of the poorly water-soluble active vitamin E acetate from oil/water nanoemulsions containing canola oil, CremophorRH40(®) and Span80(®) prepared using a low energy emulsification method (EPI process). Drug release was measured via dialysis sac and reverse dialysis sac methods as well as USP apparatus 4 fitted with dialysis sac adapters. Macro- and microscopic stability were evaluated and no instabilities were observed during the test period. In vitro release testing was adequately performed using the reverse dialysis sac and USP apparatus 4 methods. However, the dialysis method produced a slower release rate compared to the other methods and this was considered a result of violation of sink conditions within the dialysis sacs as well as inadequate mixing. Micellar solubilization was able to increase vitamin E transport from canola oil to buffer solution, but no model active concentration increase in the nanoemulsion external aqueous phase was observed despite the presence of micelles. Accordingly, it appeared that diffusion across the interfacial film was the rate-limiting step for in vitro release from these nanoemulsions. Sustained/prolonged release of vitamin E was observed and could be explained based on the high partition coefficient and on the nanoemulsion interfacial film proprieties." @default.
- W2017106076 created "2016-06-24" @default.
- W2017106076 creator A5050247514 @default.
- W2017106076 creator A5089510416 @default.
- W2017106076 date "2014-11-01" @default.
- W2017106076 modified "2023-10-12" @default.
- W2017106076 title "In vitro release testing methods for vitamin E nanoemulsions" @default.
- W2017106076 cites W1556789333 @default.
- W2017106076 cites W1560080685 @default.
- W2017106076 cites W1664986234 @default.
- W2017106076 cites W1964612962 @default.
- W2017106076 cites W1972742905 @default.
- W2017106076 cites W1976774076 @default.
- W2017106076 cites W1980237153 @default.
- W2017106076 cites W1981649078 @default.
- W2017106076 cites W1982777469 @default.
- W2017106076 cites W1982886333 @default.
- W2017106076 cites W1993600259 @default.
- W2017106076 cites W1994404104 @default.
- W2017106076 cites W1995539191 @default.
- W2017106076 cites W1995732741 @default.
- W2017106076 cites W1997349323 @default.
- W2017106076 cites W1998380582 @default.
- W2017106076 cites W2016195561 @default.
- W2017106076 cites W2024055851 @default.
- W2017106076 cites W2027978055 @default.
- W2017106076 cites W2032278830 @default.
- W2017106076 cites W2032486040 @default.
- W2017106076 cites W2038184707 @default.
- W2017106076 cites W2040521258 @default.
- W2017106076 cites W2041657387 @default.
- W2017106076 cites W2048547440 @default.
- W2017106076 cites W2048933340 @default.
- W2017106076 cites W2053215456 @default.
- W2017106076 cites W2053274664 @default.
- W2017106076 cites W2056812747 @default.
- W2017106076 cites W2059354422 @default.
- W2017106076 cites W2061110615 @default.
- W2017106076 cites W2062342181 @default.
- W2017106076 cites W2066264050 @default.
- W2017106076 cites W2067259572 @default.
- W2017106076 cites W2067314913 @default.
- W2017106076 cites W2079440572 @default.
- W2017106076 cites W2079493003 @default.
- W2017106076 cites W2093141188 @default.
- W2017106076 cites W2096215284 @default.
- W2017106076 cites W2100605804 @default.
- W2017106076 cites W2124648368 @default.
- W2017106076 cites W2130362227 @default.
- W2017106076 cites W2140468711 @default.
- W2017106076 cites W2218152871 @default.
- W2017106076 cites W2278664608 @default.
- W2017106076 cites W2314365409 @default.
- W2017106076 cites W2792456291 @default.
- W2017106076 doi "https://doi.org/10.1016/j.ijpharm.2014.08.063" @default.
- W2017106076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25178829" @default.
- W2017106076 hasPublicationYear "2014" @default.
- W2017106076 type Work @default.
- W2017106076 sameAs 2017106076 @default.
- W2017106076 citedByCount "38" @default.
- W2017106076 countsByYear W20171060762014 @default.
- W2017106076 countsByYear W20171060762015 @default.
- W2017106076 countsByYear W20171060762016 @default.
- W2017106076 countsByYear W20171060762017 @default.
- W2017106076 countsByYear W20171060762018 @default.
- W2017106076 countsByYear W20171060762019 @default.
- W2017106076 countsByYear W20171060762020 @default.
- W2017106076 countsByYear W20171060762021 @default.
- W2017106076 countsByYear W20171060762022 @default.
- W2017106076 countsByYear W20171060762023 @default.
- W2017106076 crossrefType "journal-article" @default.
- W2017106076 hasAuthorship W2017106076A5050247514 @default.
- W2017106076 hasAuthorship W2017106076A5089510416 @default.
- W2017106076 hasConcept C11268172 @default.
- W2017106076 hasConcept C141071460 @default.
- W2017106076 hasConcept C149556010 @default.
- W2017106076 hasConcept C178790620 @default.
- W2017106076 hasConcept C184651966 @default.
- W2017106076 hasConcept C185592680 @default.
- W2017106076 hasConcept C192552737 @default.
- W2017106076 hasConcept C199091049 @default.
- W2017106076 hasConcept C2776940978 @default.
- W2017106076 hasConcept C2779978075 @default.
- W2017106076 hasConcept C41625074 @default.
- W2017106076 hasConcept C43617362 @default.
- W2017106076 hasConcept C45904493 @default.
- W2017106076 hasConcept C55493867 @default.
- W2017106076 hasConcept C71924100 @default.
- W2017106076 hasConcept C96616956 @default.
- W2017106076 hasConcept C98274493 @default.
- W2017106076 hasConceptScore W2017106076C11268172 @default.
- W2017106076 hasConceptScore W2017106076C141071460 @default.
- W2017106076 hasConceptScore W2017106076C149556010 @default.
- W2017106076 hasConceptScore W2017106076C178790620 @default.
- W2017106076 hasConceptScore W2017106076C184651966 @default.
- W2017106076 hasConceptScore W2017106076C185592680 @default.
- W2017106076 hasConceptScore W2017106076C192552737 @default.
- W2017106076 hasConceptScore W2017106076C199091049 @default.