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- W2017110636 abstract "Abstract When lysozyme is dissolved in a neutral HEPES buffer solution (pH = 7.4) with 0.001–0.050 M TCEP added, a fast phase transition process occurs and the resulting novel fiber‐like hierarchical supramolecular assemblies made by primary spherical‐particle aggregation can function as a “superglue” that binds strongly and quickly onto non‐fouling coatings. This binding is highly selective towards lysozyme, and excludes synthetic, chemical/physical activation/deactivation (blocking) steps. By using biotinylated lysozyme, such a phase transition quickly creates a perfect biotinylated surface on non‐fouling surfaces for avidin binding, showing great potential for the development of low‐cost and practical biochips. magnified image" @default.
- W2017110636 created "2016-06-24" @default.
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- W2017110636 date "2012-06-18" @default.
- W2017110636 modified "2023-10-18" @default.
- W2017110636 title "Direct Biomolecule Binding on Nonfouling Surfaces via Newly Discovered Supramolecular Self-Assembly of Lysozyme under Physiological Conditions" @default.
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- W2017110636 doi "https://doi.org/10.1002/mabi.201200092" @default.
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