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- W2017117718 abstract "Objective The present retrospective study aimed to analyze the optimal time to initiate enteral nutrition (EN) in patients with severe acute pancreatitis at a single Chinese institution (China Medical University Hospital). Methods A total of 1196 patients with severe acute pancreatitis were admitted in the intensive care unit between November 2003 and June 2013; 1092 patients were selected and were divided into the early and delayed EN groups, according to their initial timing of EN. Results Five hundred sixty-six patients were administered with the delayed EN, and 526 with the early EN. Both groups had similar severity of pancreatic necrosis, but organ failure developed in 81% patients of the delayed EN group and 21% in the early EN group (P < 0.01). The numbers of septic necrosis and morbidity were significantly higher in the delayed EN group than in the early EN (P < 0.01). Conclusions The early EN had significant benefits over the delayed EN in the decrease of organ failure and mortality; our findings suggested that the first 48 hours of administration in the intensive care unit was the optimal time to start EN." @default.
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- W2017117718 date "2015-04-01" @default.
- W2017117718 modified "2023-09-30" @default.
- W2017117718 title "When to Initialize Enteral Nutrition in Patients With Severe Acute Pancreatitis?" @default.
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- W2017117718 doi "https://doi.org/10.1097/mpa.0000000000000293" @default.
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