Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017130389> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2017130389 abstract "Due to its function, the peroxisome proliferative activated receptor-gamma, coactivator-1alpha (PPARGC1A) gene is a candidate in the search for genes that may affect production traits in the pig. The purpose of this study was to screen for new SNPs in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits. Altogether 736 pigs representing five breeds Polish Landrace, n=242; Polish Large White, n=192; Hampshire, n=27; Duroc, 21; Pietrain, n=12) and synthetic line 990 (n=242) were scanned via SSCP assay. Four SNPs were found; two new ones: C/G (His338Gln) and G/A Thr359Thr), and two previously reported ones: C/A (Arg369Arg) and T/A Cys430Ser). The missense T/A and C/G SNPs demonstrated pronounced interbreed variability in terms of allele frequencies, including the exclusive presence of the C/G substitution in the Hampshire breed. The tested SNPs occurred in five putative haplotypes, and their frequency also differed substantially between breeds. The association of the SNPs with production traits was tested for G/A (Thr359Thr), C/A (Arg369Arg) and T/A (Cys430Ser) substitutions in Polish Large White, Polish Landrace and line 990. The analysis revealed only breed-specific associations. The T/A (Cys430Ser) SNP was related to the feed conversion ratio in the Polish Large White (P=0.02), and the silent G/A and C/A substitutions were respectively associated with abdominal fat in line 990 and backfat thickness in Polish Landrace (P=0.04). The combined effects of the substitutions were estimated as haplotype effects. Three significant contrasts between haplotypes were calculated, but the observed associations were again only breed-specific." @default.
- W2017130389 created "2016-06-24" @default.
- W2017130389 creator A5000180587 @default.
- W2017130389 creator A5033363992 @default.
- W2017130389 creator A5066290124 @default.
- W2017130389 creator A5079143748 @default.
- W2017130389 date "2007-01-01" @default.
- W2017130389 modified "2023-10-14" @default.
- W2017130389 title "SNPs in the porcine PPARGC1a gene: Interbreed differences and their phenotypic effects" @default.
- W2017130389 cites W1964876127 @default.
- W2017130389 cites W1971082641 @default.
- W2017130389 cites W1974079693 @default.
- W2017130389 cites W2008632158 @default.
- W2017130389 cites W2028026629 @default.
- W2017130389 cites W2030180558 @default.
- W2017130389 cites W2045449691 @default.
- W2017130389 cites W2046566365 @default.
- W2017130389 cites W2104879162 @default.
- W2017130389 cites W2112562553 @default.
- W2017130389 cites W2133370719 @default.
- W2017130389 cites W2414802231 @default.
- W2017130389 cites W4230633117 @default.
- W2017130389 doi "https://doi.org/10.2478/s11658-006-0066-7" @default.
- W2017130389 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6275938" @default.
- W2017130389 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17149556" @default.
- W2017130389 hasPublicationYear "2007" @default.
- W2017130389 type Work @default.
- W2017130389 sameAs 2017130389 @default.
- W2017130389 citedByCount "26" @default.
- W2017130389 countsByYear W20171303892012 @default.
- W2017130389 countsByYear W20171303892013 @default.
- W2017130389 countsByYear W20171303892014 @default.
- W2017130389 countsByYear W20171303892018 @default.
- W2017130389 countsByYear W20171303892021 @default.
- W2017130389 crossrefType "journal-article" @default.
- W2017130389 hasAuthorship W2017130389A5000180587 @default.
- W2017130389 hasAuthorship W2017130389A5033363992 @default.
- W2017130389 hasAuthorship W2017130389A5066290124 @default.
- W2017130389 hasAuthorship W2017130389A5079143748 @default.
- W2017130389 hasBestOaLocation W20171303891 @default.
- W2017130389 hasConcept C104317684 @default.
- W2017130389 hasConcept C12304452 @default.
- W2017130389 hasConcept C135763542 @default.
- W2017130389 hasConcept C139275648 @default.
- W2017130389 hasConcept C140793950 @default.
- W2017130389 hasConcept C149737253 @default.
- W2017130389 hasConcept C153209595 @default.
- W2017130389 hasConcept C180754005 @default.
- W2017130389 hasConcept C197754878 @default.
- W2017130389 hasConcept C2776482104 @default.
- W2017130389 hasConcept C3017825495 @default.
- W2017130389 hasConcept C54355233 @default.
- W2017130389 hasConcept C69991583 @default.
- W2017130389 hasConcept C77445288 @default.
- W2017130389 hasConcept C86339819 @default.
- W2017130389 hasConcept C86803240 @default.
- W2017130389 hasConceptScore W2017130389C104317684 @default.
- W2017130389 hasConceptScore W2017130389C12304452 @default.
- W2017130389 hasConceptScore W2017130389C135763542 @default.
- W2017130389 hasConceptScore W2017130389C139275648 @default.
- W2017130389 hasConceptScore W2017130389C140793950 @default.
- W2017130389 hasConceptScore W2017130389C149737253 @default.
- W2017130389 hasConceptScore W2017130389C153209595 @default.
- W2017130389 hasConceptScore W2017130389C180754005 @default.
- W2017130389 hasConceptScore W2017130389C197754878 @default.
- W2017130389 hasConceptScore W2017130389C2776482104 @default.
- W2017130389 hasConceptScore W2017130389C3017825495 @default.
- W2017130389 hasConceptScore W2017130389C54355233 @default.
- W2017130389 hasConceptScore W2017130389C69991583 @default.
- W2017130389 hasConceptScore W2017130389C77445288 @default.
- W2017130389 hasConceptScore W2017130389C86339819 @default.
- W2017130389 hasConceptScore W2017130389C86803240 @default.
- W2017130389 hasIssue "2" @default.
- W2017130389 hasLocation W20171303891 @default.
- W2017130389 hasLocation W20171303892 @default.
- W2017130389 hasLocation W20171303893 @default.
- W2017130389 hasLocation W20171303894 @default.
- W2017130389 hasOpenAccess W2017130389 @default.
- W2017130389 hasPrimaryLocation W20171303891 @default.
- W2017130389 hasRelatedWork W1901150897 @default.
- W2017130389 hasRelatedWork W1966708416 @default.
- W2017130389 hasRelatedWork W2021538970 @default.
- W2017130389 hasRelatedWork W2072704524 @default.
- W2017130389 hasRelatedWork W2134627737 @default.
- W2017130389 hasRelatedWork W2176187393 @default.
- W2017130389 hasRelatedWork W2283861756 @default.
- W2017130389 hasRelatedWork W2327017833 @default.
- W2017130389 hasRelatedWork W2360977025 @default.
- W2017130389 hasRelatedWork W860817473 @default.
- W2017130389 hasVolume "12" @default.
- W2017130389 isParatext "false" @default.
- W2017130389 isRetracted "false" @default.
- W2017130389 magId "2017130389" @default.
- W2017130389 workType "article" @default.