Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017133083> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2017133083 endingPage "1058" @default.
- W2017133083 startingPage "1058" @default.
- W2017133083 abstract "The ability of the newborn kidney to reabsorp filtered bicarbonate seems to be limited when compared to that of the adult kidney. This may be due to renal or extrarenal factors which are still ill-defined. Bicarbonate handling during acute acid-base changes was studied in newborn rabbits before the end of nephrogenesis. Fourty anesthetized mechanically-ventilated rabbits aged 5-12 days were studied during hypercapnic acidosis, metabolic acidosis or metabolic alkalosis. Inulin was used as a marker of glomerular filtration rate. Control newborn rabbits were in a state of hypochloremic metabolic alkalosis (blood pH 7.49, HCO3 31 mmol/l, Cl 83 mmol/l) which was not present in adult rabbits (pH 7.41, HCO3 19.5, Cl 100). This was ascribed to elevated urinary chloride losses in the first weeks of life. Hypercapnia with a PaCO2 of 80-100 mm Hg induced a significant rise in bicarbonate reabsorption, resulting in a possitive correlation between bicarbonate reabsorption and PaCO2 (y= 20.4 + 0.15 x, r= 0.86, p<0.01). During metabolic acidosis induced by infusing NH4Cl and metabolic alkalosis induced by infusing NaHCO3, bicarbonate reabsorption was mainly dependent on the filtered bicarbonate load in a wide range of serum bicarbonate levels (from 19 to 39 mmol/L). We conclude that in the chloride losing alkalemic newborn rabbit, bicarbonate renal handling responds to the same physiologic variables as present in adult animals." @default.
- W2017133083 created "2016-06-24" @default.
- W2017133083 creator A5055431896 @default.
- W2017133083 creator A5063121881 @default.
- W2017133083 creator A5064546726 @default.
- W2017133083 date "1986-10-01" @default.
- W2017133083 modified "2023-10-18" @default.
- W2017133083 title "143 THE INFLUENCE OF ACUTE ACID-BASE CHANGES ON BICARBONATE HANDLING IN TJE NEWBORN RABBIT" @default.
- W2017133083 doi "https://doi.org/10.1203/00006450-198610000-00198" @default.
- W2017133083 hasPublicationYear "1986" @default.
- W2017133083 type Work @default.
- W2017133083 sameAs 2017133083 @default.
- W2017133083 citedByCount "0" @default.
- W2017133083 crossrefType "journal-article" @default.
- W2017133083 hasAuthorship W2017133083A5055431896 @default.
- W2017133083 hasAuthorship W2017133083A5063121881 @default.
- W2017133083 hasAuthorship W2017133083A5064546726 @default.
- W2017133083 hasBestOaLocation W20171330831 @default.
- W2017133083 hasConcept C126322002 @default.
- W2017133083 hasConcept C134018914 @default.
- W2017133083 hasConcept C134746045 @default.
- W2017133083 hasConcept C185592680 @default.
- W2017133083 hasConcept C2777068682 @default.
- W2017133083 hasConcept C2778553927 @default.
- W2017133083 hasConcept C2779246250 @default.
- W2017133083 hasConcept C2779539245 @default.
- W2017133083 hasConcept C2780091579 @default.
- W2017133083 hasConcept C2781112554 @default.
- W2017133083 hasConcept C56906281 @default.
- W2017133083 hasConcept C71924100 @default.
- W2017133083 hasConceptScore W2017133083C126322002 @default.
- W2017133083 hasConceptScore W2017133083C134018914 @default.
- W2017133083 hasConceptScore W2017133083C134746045 @default.
- W2017133083 hasConceptScore W2017133083C185592680 @default.
- W2017133083 hasConceptScore W2017133083C2777068682 @default.
- W2017133083 hasConceptScore W2017133083C2778553927 @default.
- W2017133083 hasConceptScore W2017133083C2779246250 @default.
- W2017133083 hasConceptScore W2017133083C2779539245 @default.
- W2017133083 hasConceptScore W2017133083C2780091579 @default.
- W2017133083 hasConceptScore W2017133083C2781112554 @default.
- W2017133083 hasConceptScore W2017133083C56906281 @default.
- W2017133083 hasConceptScore W2017133083C71924100 @default.
- W2017133083 hasIssue "10" @default.
- W2017133083 hasLocation W20171330831 @default.
- W2017133083 hasOpenAccess W2017133083 @default.
- W2017133083 hasPrimaryLocation W20171330831 @default.
- W2017133083 hasRelatedWork W189729881 @default.
- W2017133083 hasRelatedWork W2017133083 @default.
- W2017133083 hasRelatedWork W2047363536 @default.
- W2017133083 hasRelatedWork W2125491946 @default.
- W2017133083 hasRelatedWork W2167759319 @default.
- W2017133083 hasRelatedWork W2206459557 @default.
- W2017133083 hasRelatedWork W2398239885 @default.
- W2017133083 hasRelatedWork W2414209570 @default.
- W2017133083 hasRelatedWork W2466816360 @default.
- W2017133083 hasRelatedWork W4290348130 @default.
- W2017133083 hasVolume "20" @default.
- W2017133083 isParatext "false" @default.
- W2017133083 isRetracted "false" @default.
- W2017133083 magId "2017133083" @default.
- W2017133083 workType "article" @default.