FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017134595> ?p ?o ?g. }

• W2017134595 endingPage "180" @default.
• W2017134595 startingPage "174" @default.
• W2017134595 abstract "A new delivery system for cutaneous administration combining the advantages of cyclodextrin inclusion complexes and those of deformable liposomes was developed, leading to a new concept: drug-in-cyclodextrin-in-deformable liposomes. Deformable liposomes made of soybean phosphatidylcholine (PC) or dimyristoylphosphatidylcholine (DMPC) and sodium deoxycholate as edge activator were compared to classical non-deformable liposomes. Liposomes were prepared by the film evaporation method. Betamethasone, chosen as the model drug, was encapsulated in the aqueous cavity of liposomes by the use of cyclodextrins. Cyclodextrins allow an increase in the aqueous solubility of betamethasone and thus, the encapsulation efficiency in liposome vesicles. Liposome size, deformability and encapsulation efficiency were calculated. The best results were obtained with deformable liposomes made of PC in comparison with DMPC. The stability of PC vesicles was evaluated by measuring the leakage of encapsulated calcein on the one hand and the leakage of encapsulated betamethasone on the other hand. In vitro diffusion studies were carried out on Franz type diffusion cells through polycarbonate membranes. In comparison with non-deformable liposomes, these new vesicles showed improved encapsulation efficiency, good stability and higher in vitro diffusion percentages of encapsulated drug. They are therefore promising for future use in ex vivo and in vivo experiments." @default.
• W2017134595 created "2016-06-24" @default.
• W2017134595 creator A5016406373 @default.
• W2017134595 creator A5019391624 @default.
• W2017134595 creator A5038645086 @default.
• W2017134595 creator A5084708096 @default.
• W2017134595 creator A5090765919 @default.
• W2017134595 date "2009-10-01" @default.
• W2017134595 modified "2023-10-16" @default.
• W2017134595 title "Development of a new topical system: Drug-in-cyclodextrin-in-deformable liposome" @default.
• W2017134595 cites W1964015173 @default.
• W2017134595 cites W1981398993 @default.
• W2017134595 cites W1987078254 @default.
• W2017134595 cites W1990107938 @default.
• W2017134595 cites W1999424668 @default.
• W2017134595 cites W2009691452 @default.
• W2017134595 cites W2014093866 @default.
• W2017134595 cites W2018179688 @default.
• W2017134595 cites W2029383767 @default.
• W2017134595 cites W2047817628 @default.
• W2017134595 cites W2056045451 @default.
• W2017134595 cites W2058009653 @default.
• W2017134595 cites W2064048353 @default.
• W2017134595 cites W2064776678 @default.
• W2017134595 cites W2069309957 @default.
• W2017134595 cites W2081583435 @default.
• W2017134595 cites W2102109292 @default.
• W2017134595 cites W2158652535 @default.
• W2017134595 cites W2161034880 @default.
• W2017134595 doi "https://doi.org/10.1016/j.ijpharm.2009.06.027" @default.
• W2017134595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19576972" @default.
• W2017134595 hasPublicationYear "2009" @default.
• W2017134595 type Work @default.
• W2017134595 sameAs 2017134595 @default.
• W2017134595 citedByCount "71" @default.
• W2017134595 countsByYear W20171345952012 @default.
• W2017134595 countsByYear W20171345952013 @default.
• W2017134595 countsByYear W20171345952014 @default.
• W2017134595 countsByYear W20171345952015 @default.
• W2017134595 countsByYear W20171345952016 @default.
• W2017134595 countsByYear W20171345952017 @default.
• W2017134595 countsByYear W20171345952018 @default.
• W2017134595 countsByYear W20171345952019 @default.
• W2017134595 countsByYear W20171345952020 @default.
• W2017134595 countsByYear W20171345952021 @default.
• W2017134595 countsByYear W20171345952022 @default.
• W2017134595 countsByYear W20171345952023 @default.
• W2017134595 crossrefType "journal-article" @default.
• W2017134595 hasAuthorship W2017134595A5016406373 @default.
• W2017134595 hasAuthorship W2017134595A5019391624 @default.
• W2017134595 hasAuthorship W2017134595A5038645086 @default.
• W2017134595 hasAuthorship W2017134595A5084708096 @default.
• W2017134595 hasAuthorship W2017134595A5090765919 @default.
• W2017134595 hasConcept C12554922 @default.
• W2017134595 hasConcept C130316041 @default.
• W2017134595 hasConcept C178790620 @default.
• W2017134595 hasConcept C185154212 @default.
• W2017134595 hasConcept C185592680 @default.
• W2017134595 hasConcept C2776330855 @default.
• W2017134595 hasConcept C2776872141 @default.
• W2017134595 hasConcept C2778918659 @default.
• W2017134595 hasConcept C2779433975 @default.
• W2017134595 hasConcept C2779820397 @default.
• W2017134595 hasConcept C41625074 @default.
• W2017134595 hasConcept C43617362 @default.
• W2017134595 hasConcept C55493867 @default.
• W2017134595 hasConcept C86803240 @default.
• W2017134595 hasConceptScore W2017134595C12554922 @default.
• W2017134595 hasConceptScore W2017134595C130316041 @default.
• W2017134595 hasConceptScore W2017134595C178790620 @default.
• W2017134595 hasConceptScore W2017134595C185154212 @default.
• W2017134595 hasConceptScore W2017134595C185592680 @default.
• W2017134595 hasConceptScore W2017134595C2776330855 @default.
• W2017134595 hasConceptScore W2017134595C2776872141 @default.
• W2017134595 hasConceptScore W2017134595C2778918659 @default.
• W2017134595 hasConceptScore W2017134595C2779433975 @default.
• W2017134595 hasConceptScore W2017134595C2779820397 @default.
• W2017134595 hasConceptScore W2017134595C41625074 @default.
• W2017134595 hasConceptScore W2017134595C43617362 @default.
• W2017134595 hasConceptScore W2017134595C55493867 @default.
• W2017134595 hasConceptScore W2017134595C86803240 @default.
• W2017134595 hasIssue "1-2" @default.
• W2017134595 hasLocation W20171345951 @default.
• W2017134595 hasLocation W20171345952 @default.
• W2017134595 hasOpenAccess W2017134595 @default.
• W2017134595 hasPrimaryLocation W20171345951 @default.
• W2017134595 hasRelatedWork W13190771 @default.
• W2017134595 hasRelatedWork W2025441926 @default.
• W2017134595 hasRelatedWork W2030924644 @default.
• W2017134595 hasRelatedWork W2036919370 @default.
• W2017134595 hasRelatedWork W2079657570 @default.
• W2017134595 hasRelatedWork W2101132035 @default.
• W2017134595 hasRelatedWork W2247479559 @default.
• W2017134595 hasRelatedWork W2969136920 @default.
• W2017134595 hasRelatedWork W3092297591 @default.
• W2017134595 hasRelatedWork W3164665447 @default.
• W2017134595 hasVolume "380" @default.
• W2017134595 isParatext "false" @default.

• next