Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017135961> ?p ?o ?g. }
- W2017135961 endingPage "545" @default.
- W2017135961 startingPage "536" @default.
- W2017135961 abstract "Diffusion tensor imaging (DTI) studies have reported substantial white matter abnormalities in patients with temporal lobe epilepsy (TLE). However, limited data exist regarding the extent of white matter tract abnormalities, cognitive effects of these abnormalities, and relationship to clinical factors. The current study examined these issues in subjects with chronic TLE.DTI data were obtained in 12 TLE subjects and 10 age-matched healthy controls. Voxel-wise statistical analysis of fractional anisotropy (FA) was carried out using tract-based spatial statistics (TBSS). White matter integrity was correlated with cognitive performance and epilepsy-related clinical parameters.Subjects with TLE, as compared to healthy controls, demonstrated four clusters of reduced FA, in anterior temporal lobe, mesial temporal lobe, and cerebellum ipsilateral, as well as frontoparietal lobe contralateral to the side of seizure onset. Mean FA was positively correlated with delayed memory, in anterior temporal lobe; and immediate memory, in mesial temporal lobe. Lower FA values in the posterior region of corpus callosum were related to earlier age of seizure onset.TLE is associated with widespread disturbances in white matter tracts and these changes have important cognitive and clinical consequences." @default.
- W2017135961 created "2016-06-24" @default.
- W2017135961 creator A5007795058 @default.
- W2017135961 creator A5012744570 @default.
- W2017135961 creator A5019518085 @default.
- W2017135961 creator A5029975016 @default.
- W2017135961 creator A5032570790 @default.
- W2017135961 creator A5037354000 @default.
- W2017135961 creator A5079885275 @default.
- W2017135961 date "2010-04-01" @default.
- W2017135961 modified "2023-10-15" @default.
- W2017135961 title "Altered white matter integrity in temporal lobe epilepsy: Association with cognitive and clinical profiles" @default.
- W2017135961 cites W1512859146 @default.
- W2017135961 cites W1965400726 @default.
- W2017135961 cites W1965841995 @default.
- W2017135961 cites W1966104090 @default.
- W2017135961 cites W1966144490 @default.
- W2017135961 cites W1968195255 @default.
- W2017135961 cites W1975222210 @default.
- W2017135961 cites W1981786093 @default.
- W2017135961 cites W1984520089 @default.
- W2017135961 cites W1984578164 @default.
- W2017135961 cites W1990231887 @default.
- W2017135961 cites W1996370913 @default.
- W2017135961 cites W2000133863 @default.
- W2017135961 cites W2024046025 @default.
- W2017135961 cites W2032611982 @default.
- W2017135961 cites W2033049536 @default.
- W2017135961 cites W2036447011 @default.
- W2017135961 cites W2048878685 @default.
- W2017135961 cites W2053138442 @default.
- W2017135961 cites W2053384222 @default.
- W2017135961 cites W2055893993 @default.
- W2017135961 cites W2059177186 @default.
- W2017135961 cites W2060449369 @default.
- W2017135961 cites W2066568599 @default.
- W2017135961 cites W2070626500 @default.
- W2017135961 cites W2071633720 @default.
- W2017135961 cites W2071881327 @default.
- W2017135961 cites W2088858238 @default.
- W2017135961 cites W2088963917 @default.
- W2017135961 cites W2092014599 @default.
- W2017135961 cites W2097816953 @default.
- W2017135961 cites W2099295649 @default.
- W2017135961 cites W2101302195 @default.
- W2017135961 cites W2102753837 @default.
- W2017135961 cites W2104284834 @default.
- W2017135961 cites W2105177506 @default.
- W2017135961 cites W2106485269 @default.
- W2017135961 cites W2107187807 @default.
- W2017135961 cites W2113576511 @default.
- W2017135961 cites W2117461354 @default.
- W2017135961 cites W2118932004 @default.
- W2017135961 cites W2120168996 @default.
- W2017135961 cites W2120357670 @default.
- W2017135961 cites W2120457869 @default.
- W2017135961 cites W2127623225 @default.
- W2017135961 cites W2148726987 @default.
- W2017135961 cites W2154173184 @default.
- W2017135961 cites W2166627169 @default.
- W2017135961 cites W2173317214 @default.
- W2017135961 doi "https://doi.org/10.1111/j.1528-1167.2009.02508.x" @default.
- W2017135961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2929974" @default.
- W2017135961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20132296" @default.
- W2017135961 hasPublicationYear "2010" @default.
- W2017135961 type Work @default.
- W2017135961 sameAs 2017135961 @default.
- W2017135961 citedByCount "145" @default.
- W2017135961 countsByYear W20171359612012 @default.
- W2017135961 countsByYear W20171359612013 @default.
- W2017135961 countsByYear W20171359612014 @default.
- W2017135961 countsByYear W20171359612015 @default.
- W2017135961 countsByYear W20171359612016 @default.
- W2017135961 countsByYear W20171359612017 @default.
- W2017135961 countsByYear W20171359612018 @default.
- W2017135961 countsByYear W20171359612019 @default.
- W2017135961 countsByYear W20171359612020 @default.
- W2017135961 countsByYear W20171359612021 @default.
- W2017135961 countsByYear W20171359612022 @default.
- W2017135961 countsByYear W20171359612023 @default.
- W2017135961 crossrefType "journal-article" @default.
- W2017135961 hasAuthorship W2017135961A5007795058 @default.
- W2017135961 hasAuthorship W2017135961A5012744570 @default.
- W2017135961 hasAuthorship W2017135961A5019518085 @default.
- W2017135961 hasAuthorship W2017135961A5029975016 @default.
- W2017135961 hasAuthorship W2017135961A5032570790 @default.
- W2017135961 hasAuthorship W2017135961A5037354000 @default.
- W2017135961 hasAuthorship W2017135961A5079885275 @default.
- W2017135961 hasBestOaLocation W20171359611 @default.
- W2017135961 hasConcept C126838900 @default.
- W2017135961 hasConcept C143409427 @default.
- W2017135961 hasConcept C149550507 @default.
- W2017135961 hasConcept C15744967 @default.
- W2017135961 hasConcept C169760540 @default.
- W2017135961 hasConcept C2778183499 @default.
- W2017135961 hasConcept C2778186239 @default.
- W2017135961 hasConcept C2781099131 @default.
- W2017135961 hasConcept C2781192897 @default.