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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017141997> ?p ?o ?g. }

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• W2017141997 abstract "Therapeutic vaccination combined with new drugs may cure multiple myeloma (MM). We have developed a bio-process to purify CMRF-56 monoclonal antibody (mAb) and a standard operating procedure to immunoselect blood dendritic cells (BDC). Leucopheresed mononuclear cells were cultured overnight, labelled with CMRF-56 mAb and BDC prepared using a clinical scale immunoselection system. The mean BDC yield from healthy donors was 48% (n = 6, purity 28%). Preparations from MM patients (n = 6, yield 47%, purity 35%) primed cytotoxic T lymphocytes (CTL) to clinically relevant MM antigens. This procedure can be performed readily by clinical cell manufacturing units to facilitate BDC vaccination studies." @default.
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• W2017141997 date "2008-11-01" @default.
• W2017141997 modified "2023-10-16" @default.
• W2017141997 title "Practical blood dendritic cell vaccination for immunotherapy of multiple myeloma" @default.
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• W2017141997 doi "https://doi.org/10.1111/j.1365-2141.2008.07346.x" @default.
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