FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017148964> ?p ?o ?g. }

• W2017148964 endingPage "374" @default.
• W2017148964 startingPage "364" @default.
• W2017148964 abstract "Abstract The rat adrenal hormone corticosterone binds to low and high affinity receptors, discretely localized in brain, including the dentate gyrus. Differential activation of the two receptor types under physiological conditions alters gene expression and functional characteristics of hippocampal neurones. In the present study we examined gene expression of electrophysiologically identified dentate granule cells, 1 day after 21 days of unpredictable stress or control treatment, both under basal corticosteroid conditions and after brief in vitro exposure to a high dose of corticosterone. From each cell, RNA was collected, linearly amplified and hybridized with cDNA clones for three calcium channel subunits, four NMDA, two AMPA and 11 GABA receptor subunits. We found that gene expression was not extensively changed after chronic stress when neurones were studied under basal corticosteroid conditions. However, combined with acute exposure to a high corticosterone dose, relative expression of eight transcripts was significantly altered, including a consistent up‐regulation of GABAa receptor α1 and down‐regulation of calcium channel α1A and α1G subunit expression. If translated to the protein level, this may result in more transient GABAa receptor mediated responses and less transient calcium influx. This could contribute to enhanced excitability and vulnerability of granule cells after chronic stress." @default.
• W2017148964 created "2016-06-24" @default.
• W2017148964 creator A5064798164 @default.
• W2017148964 creator A5069823044 @default.
• W2017148964 creator A5077705713 @default.
• W2017148964 date "2004-03-22" @default.
• W2017148964 modified "2023-10-16" @default.
• W2017148964 title "Chronic unpredictable stress alters gene expression in rat single dentate granule cells" @default.
• W2017148964 cites W1563232002 @default.
• W2017148964 cites W1600539804 @default.
• W2017148964 cites W1905334019 @default.
• W2017148964 cites W1966152670 @default.
• W2017148964 cites W1982715118 @default.
• W2017148964 cites W1989762673 @default.
• W2017148964 cites W1991842868 @default.
• W2017148964 cites W1997544112 @default.
• W2017148964 cites W1997568797 @default.
• W2017148964 cites W2009613516 @default.
• W2017148964 cites W2019700505 @default.
• W2017148964 cites W2029650881 @default.
• W2017148964 cites W2034694738 @default.
• W2017148964 cites W2038862185 @default.
• W2017148964 cites W2049156416 @default.
• W2017148964 cites W2055065216 @default.
• W2017148964 cites W2060267954 @default.
• W2017148964 cites W2063394935 @default.
• W2017148964 cites W2064310011 @default.
• W2017148964 cites W2065464942 @default.
• W2017148964 cites W2068508628 @default.
• W2017148964 cites W2080001278 @default.
• W2017148964 cites W2082076549 @default.
• W2017148964 cites W2084802678 @default.
• W2017148964 cites W2085122189 @default.
• W2017148964 cites W2091322528 @default.
• W2017148964 cites W2112164108 @default.
• W2017148964 cites W2112354679 @default.
• W2017148964 cites W2113962949 @default.
• W2017148964 cites W2133819402 @default.
• W2017148964 cites W2144797074 @default.
• W2017148964 cites W2152199882 @default.
• W2017148964 cites W2152541584 @default.
• W2017148964 cites W2153522818 @default.
• W2017148964 cites W2159040523 @default.
• W2017148964 cites W333671105 @default.
• W2017148964 cites W4294443837 @default.
• W2017148964 doi "https://doi.org/10.1111/j.1471-4159.2003.02332.x" @default.
• W2017148964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15056280" @default.
• W2017148964 hasPublicationYear "2004" @default.
• W2017148964 type Work @default.
• W2017148964 sameAs 2017148964 @default.
• W2017148964 citedByCount "47" @default.
• W2017148964 countsByYear W20171489642012 @default.
• W2017148964 countsByYear W20171489642014 @default.
• W2017148964 countsByYear W20171489642015 @default.
• W2017148964 countsByYear W20171489642016 @default.
• W2017148964 countsByYear W20171489642018 @default.
• W2017148964 countsByYear W20171489642019 @default.
• W2017148964 countsByYear W20171489642020 @default.
• W2017148964 countsByYear W20171489642021 @default.
• W2017148964 countsByYear W20171489642022 @default.
• W2017148964 countsByYear W20171489642023 @default.
• W2017148964 crossrefType "journal-article" @default.
• W2017148964 hasAuthorship W2017148964A5064798164 @default.
• W2017148964 hasAuthorship W2017148964A5069823044 @default.
• W2017148964 hasAuthorship W2017148964A5077705713 @default.
• W2017148964 hasBestOaLocation W20171489641 @default.
• W2017148964 hasConcept C104317684 @default.
• W2017148964 hasConcept C126322002 @default.
• W2017148964 hasConcept C134018914 @default.
• W2017148964 hasConcept C148762608 @default.
• W2017148964 hasConcept C150194340 @default.
• W2017148964 hasConcept C160268369 @default.
• W2017148964 hasConcept C168258287 @default.
• W2017148964 hasConcept C170493617 @default.
• W2017148964 hasConcept C2776464000 @default.
• W2017148964 hasConcept C2778888523 @default.
• W2017148964 hasConcept C2780352252 @default.
• W2017148964 hasConcept C55493867 @default.
• W2017148964 hasConcept C61174792 @default.
• W2017148964 hasConcept C67018056 @default.
• W2017148964 hasConcept C71315377 @default.
• W2017148964 hasConcept C71924100 @default.
• W2017148964 hasConcept C86803240 @default.
• W2017148964 hasConcept C95444343 @default.
• W2017148964 hasConceptScore W2017148964C104317684 @default.
• W2017148964 hasConceptScore W2017148964C126322002 @default.
• W2017148964 hasConceptScore W2017148964C134018914 @default.
• W2017148964 hasConceptScore W2017148964C148762608 @default.
• W2017148964 hasConceptScore W2017148964C150194340 @default.
• W2017148964 hasConceptScore W2017148964C160268369 @default.
• W2017148964 hasConceptScore W2017148964C168258287 @default.
• W2017148964 hasConceptScore W2017148964C170493617 @default.
• W2017148964 hasConceptScore W2017148964C2776464000 @default.
• W2017148964 hasConceptScore W2017148964C2778888523 @default.
• W2017148964 hasConceptScore W2017148964C2780352252 @default.
• W2017148964 hasConceptScore W2017148964C55493867 @default.
• W2017148964 hasConceptScore W2017148964C61174792 @default.
• W2017148964 hasConceptScore W2017148964C67018056 @default.

• next