Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017148988> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2017148988 endingPage "652" @default.
- W2017148988 startingPage "648" @default.
- W2017148988 abstract "Recombinant human serum albumin (rHSA) incorporating 2-[8-{N-(2-methylimidazolyl)}octanoyloxymethyl]-5,10,15,20-tetrakis(α,α,α,α-o-pivalamido)phenylporphinatoiron(II)s (Fe(II)Ps) [rHSA−Fe(II)P] is a synthetic hemoprotein which can bind and release O2 reversibly under physiological conditions (saline solution [NaCl]: 150 mM, pH 7.3) as do hemoglobin and myoglobin. However, the central ferrous ions of Fe(II)Ps are slowly oxidized to O2-inactive ferric forms. Based on the UV−vis. absorption spectroscopy, the majority of the autooxidized Fe(III)Ps in albumin are determined to be six-coordinate high-spin complexes with a proximal imidazole and a chloride anion, which show ligand-to-metal charge transfer (LMCT) absorption at 330 nm. Interestingly, photoirradiation of this LMCT band under an argon atmosphere led to reduction of the central ferric iron of Fe(III)P, allowing the revival of the O2-binding ability. The ratio of the photoreduction reached a maximum of 83%, which is probably due to the partial dissociation of the axial imidazole. The same photoirradiation under a CO atmosphere provides the corresponding carbonyl rHSA−Fe(II)P. Laser flash photolysis experiments revealed that the reduction was completed within 100 ns. The quantum yields (Φ) of these photoreductions were approximately 0.01." @default.
- W2017148988 created "2016-06-24" @default.
- W2017148988 creator A5028484085 @default.
- W2017148988 creator A5070166950 @default.
- W2017148988 creator A5081550370 @default.
- W2017148988 date "2001-06-14" @default.
- W2017148988 modified "2023-10-03" @default.
- W2017148988 title "Photoreduction of Autooxidized Albumin−Heme Hybrid in Saline Solution: Revival of Its O<sub>2</sub>-Binding Ability" @default.
- W2017148988 cites W1964973534 @default.
- W2017148988 cites W1978706394 @default.
- W2017148988 cites W1978719964 @default.
- W2017148988 cites W1996581943 @default.
- W2017148988 cites W2032218083 @default.
- W2017148988 cites W2053086685 @default.
- W2017148988 cites W2078490118 @default.
- W2017148988 cites W2093433377 @default.
- W2017148988 cites W2106053531 @default.
- W2017148988 cites W3004625066 @default.
- W2017148988 doi "https://doi.org/10.1021/bc000106j" @default.
- W2017148988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11459472" @default.
- W2017148988 hasPublicationYear "2001" @default.
- W2017148988 type Work @default.
- W2017148988 sameAs 2017148988 @default.
- W2017148988 citedByCount "8" @default.
- W2017148988 crossrefType "journal-article" @default.
- W2017148988 hasAuthorship W2017148988A5028484085 @default.
- W2017148988 hasAuthorship W2017148988A5070166950 @default.
- W2017148988 hasAuthorship W2017148988A5081550370 @default.
- W2017148988 hasConcept C102931765 @default.
- W2017148988 hasConcept C119824511 @default.
- W2017148988 hasConcept C121332964 @default.
- W2017148988 hasConcept C125287762 @default.
- W2017148988 hasConcept C13472781 @default.
- W2017148988 hasConcept C148898269 @default.
- W2017148988 hasConcept C178790620 @default.
- W2017148988 hasConcept C179104552 @default.
- W2017148988 hasConcept C181199279 @default.
- W2017148988 hasConcept C185592680 @default.
- W2017148988 hasConcept C20705724 @default.
- W2017148988 hasConcept C24890656 @default.
- W2017148988 hasConcept C2775832776 @default.
- W2017148988 hasConcept C2776217839 @default.
- W2017148988 hasConcept C2778063876 @default.
- W2017148988 hasConcept C2778597219 @default.
- W2017148988 hasConcept C2780534640 @default.
- W2017148988 hasConcept C2780874372 @default.
- W2017148988 hasConcept C43617362 @default.
- W2017148988 hasConcept C62520636 @default.
- W2017148988 hasConcept C71240020 @default.
- W2017148988 hasConcept C75473681 @default.
- W2017148988 hasConcept C93391505 @default.
- W2017148988 hasConceptScore W2017148988C102931765 @default.
- W2017148988 hasConceptScore W2017148988C119824511 @default.
- W2017148988 hasConceptScore W2017148988C121332964 @default.
- W2017148988 hasConceptScore W2017148988C125287762 @default.
- W2017148988 hasConceptScore W2017148988C13472781 @default.
- W2017148988 hasConceptScore W2017148988C148898269 @default.
- W2017148988 hasConceptScore W2017148988C178790620 @default.
- W2017148988 hasConceptScore W2017148988C179104552 @default.
- W2017148988 hasConceptScore W2017148988C181199279 @default.
- W2017148988 hasConceptScore W2017148988C185592680 @default.
- W2017148988 hasConceptScore W2017148988C20705724 @default.
- W2017148988 hasConceptScore W2017148988C24890656 @default.
- W2017148988 hasConceptScore W2017148988C2775832776 @default.
- W2017148988 hasConceptScore W2017148988C2776217839 @default.
- W2017148988 hasConceptScore W2017148988C2778063876 @default.
- W2017148988 hasConceptScore W2017148988C2778597219 @default.
- W2017148988 hasConceptScore W2017148988C2780534640 @default.
- W2017148988 hasConceptScore W2017148988C2780874372 @default.
- W2017148988 hasConceptScore W2017148988C43617362 @default.
- W2017148988 hasConceptScore W2017148988C62520636 @default.
- W2017148988 hasConceptScore W2017148988C71240020 @default.
- W2017148988 hasConceptScore W2017148988C75473681 @default.
- W2017148988 hasConceptScore W2017148988C93391505 @default.
- W2017148988 hasIssue "4" @default.
- W2017148988 hasLocation W20171489881 @default.
- W2017148988 hasLocation W20171489882 @default.
- W2017148988 hasOpenAccess W2017148988 @default.
- W2017148988 hasPrimaryLocation W20171489881 @default.
- W2017148988 hasRelatedWork W1517663550 @default.
- W2017148988 hasRelatedWork W1609000601 @default.
- W2017148988 hasRelatedWork W2016308157 @default.
- W2017148988 hasRelatedWork W2031358174 @default.
- W2017148988 hasRelatedWork W2055847384 @default.
- W2017148988 hasRelatedWork W2115249599 @default.
- W2017148988 hasRelatedWork W2154861470 @default.
- W2017148988 hasRelatedWork W2324337624 @default.
- W2017148988 hasRelatedWork W2333877587 @default.
- W2017148988 hasRelatedWork W2793778235 @default.
- W2017148988 hasVolume "12" @default.
- W2017148988 isParatext "false" @default.
- W2017148988 isRetracted "false" @default.
- W2017148988 magId "2017148988" @default.
- W2017148988 workType "article" @default.