FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017151582> ?p ?o ?g. }

• W2017151582 endingPage "77" @default.
• W2017151582 startingPage "69" @default.
• W2017151582 abstract "Chronic caffeine exerts negligible effects on learning and memory in normal adults, but it is unknown whether this is also true for children and adolescents. The hippocampus, a brain region important for learning and memory, undergoes extensive structural and functional modifications during pre-adolescence and adolescence. As a result, chronic caffeine may have differential effects on hippocampus-dependent learning in pre-adolescents and adolescents compared with adults. Here, we characterized the effects of chronic caffeine and withdrawal from chronic caffeine on hippocampus-dependent (contextual) and hippocampus-independent (cued) fear conditioning in pre-adolescent, adolescent, and adult mice. The results indicate that chronic exposure to caffeine during pre-adolescence and adolescence enhances or impairs contextual conditioning depending on concentration, yet has no effect on cued conditioning. In contrast, withdrawal from chronic caffeine impairs contextual conditioning in pre-adolescent mice only. No changes in learning were seen for adult mice for either the chronic caffeine or withdrawal conditions. These findings support the hypothesis that chronic exposure to caffeine during pre-adolescence and adolescence can alter learning and memory and as changes were only seen in hippocampus-dependent learning, which suggests that the developing hippocampus may be sensitive to the effects of caffeine." @default.
• W2017151582 created "2016-06-24" @default.
• W2017151582 creator A5047140822 @default.
• W2017151582 creator A5062646339 @default.
• W2017151582 creator A5079777792 @default.
• W2017151582 date "2016-02-01" @default.
• W2017151582 modified "2023-09-24" @default.
• W2017151582 title "Concentration- and age-dependent effects of chronic caffeine on contextual fear conditioning in C57BL/6J mice" @default.
• W2017151582 cites W1511744706 @default.
• W2017151582 cites W1514696983 @default.
• W2017151582 cites W1521038203 @default.
• W2017151582 cites W1576503935 @default.
• W2017151582 cites W1653173387 @default.
• W2017151582 cites W1924082254 @default.
• W2017151582 cites W1964871934 @default.
• W2017151582 cites W1968554828 @default.
• W2017151582 cites W1975668155 @default.
• W2017151582 cites W1980451837 @default.
• W2017151582 cites W1982717798 @default.
• W2017151582 cites W1985645068 @default.
• W2017151582 cites W1991565131 @default.
• W2017151582 cites W1992036343 @default.
• W2017151582 cites W1993353270 @default.
• W2017151582 cites W1994550202 @default.
• W2017151582 cites W1995352196 @default.
• W2017151582 cites W2001308670 @default.
• W2017151582 cites W2004980098 @default.
• W2017151582 cites W2006322693 @default.
• W2017151582 cites W2006682240 @default.
• W2017151582 cites W2008628336 @default.
• W2017151582 cites W2010158637 @default.
• W2017151582 cites W2010171011 @default.
• W2017151582 cites W2012647648 @default.
• W2017151582 cites W2012904022 @default.
• W2017151582 cites W2013082402 @default.
• W2017151582 cites W2015468094 @default.
• W2017151582 cites W2015497878 @default.
• W2017151582 cites W2016123897 @default.
• W2017151582 cites W2021751915 @default.
• W2017151582 cites W2022932475 @default.
• W2017151582 cites W2026604158 @default.
• W2017151582 cites W2028077165 @default.
• W2017151582 cites W2028299419 @default.
• W2017151582 cites W2032352281 @default.
• W2017151582 cites W2037062942 @default.
• W2017151582 cites W2037508520 @default.
• W2017151582 cites W2039648672 @default.
• W2017151582 cites W2043632247 @default.
• W2017151582 cites W2044262145 @default.
• W2017151582 cites W2049746655 @default.
• W2017151582 cites W2056769436 @default.
• W2017151582 cites W2059131332 @default.
• W2017151582 cites W2060035266 @default.
• W2017151582 cites W2068098222 @default.
• W2017151582 cites W2071793104 @default.
• W2017151582 cites W2074624311 @default.
• W2017151582 cites W2076009810 @default.
• W2017151582 cites W2076283597 @default.
• W2017151582 cites W2076578658 @default.
• W2017151582 cites W2079018544 @default.
• W2017151582 cites W2085618842 @default.
• W2017151582 cites W2088024567 @default.
• W2017151582 cites W2088102722 @default.
• W2017151582 cites W2089239490 @default.
• W2017151582 cites W2092204712 @default.
• W2017151582 cites W2092602340 @default.
• W2017151582 cites W2095352917 @default.
• W2017151582 cites W2097659555 @default.
• W2017151582 cites W2099167075 @default.
• W2017151582 cites W2104973252 @default.
• W2017151582 cites W2111977586 @default.
• W2017151582 cites W2118399240 @default.
• W2017151582 cites W2128281789 @default.
• W2017151582 cites W2136717001 @default.
• W2017151582 cites W2138287659 @default.
• W2017151582 cites W2145265000 @default.
• W2017151582 cites W2153998371 @default.
• W2017151582 cites W2164712597 @default.
• W2017151582 cites W2202736130 @default.
• W2017151582 cites W2437004909 @default.
• W2017151582 cites W336493937 @default.
• W2017151582 cites W4232755968 @default.
• W2017151582 cites W4234462787 @default.
• W2017151582 cites W4244844780 @default.
• W2017151582 cites W4245129714 @default.
• W2017151582 cites W4248968780 @default.
• W2017151582 cites W4250700650 @default.
• W2017151582 cites W4297924502 @default.
• W2017151582 cites W75676917 @default.
• W2017151582 doi "https://doi.org/10.1016/j.bbr.2015.03.045" @default.
• W2017151582 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4586291" @default.
• W2017151582 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25827925" @default.
• W2017151582 hasPublicationYear "2016" @default.
• W2017151582 type Work @default.
• W2017151582 sameAs 2017151582 @default.
• W2017151582 citedByCount "7" @default.
• W2017151582 countsByYear W20171515822016 @default.
• W2017151582 countsByYear W20171515822017 @default.

• next