Matches in SemOpenAlex for { <https://semopenalex.org/work/W201715397> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W201715397 endingPage "604" @default.
- W201715397 startingPage "598" @default.
- W201715397 abstract "To report and evaluate a conservative and individualized treatment policy in a homogeneously selected series of patients affected by pure ovarian immature teratoma.This prospective trial, with specific treatment policies according to stage and grade, was planned and started in 1982. The study population consisted of 32 patients affected by pure immature teratoma, with the exclusion of mixed germ cell tumors. Fertility-sparing surgery was performed whenever possible. Surgery alone, with careful follow-up, was adopted for stage I or II according to the International Federation of Gynecology and Obstetrics (FIGO) and grade 1 or 2 tumors. The other patients, with stage III or with grade 3 stage I or II tumors, or those referred at relapse, were treated with platinum-based chemotherapy regimens.Thirty of 32 patients underwent fertility-sparing surgery. Ten of 32 patients received chemotherapy after surgery, either as adjuvant treatment or in the presence of visible tumor. All 32 patients are alive and disease-free, with a median follow-up from surgery of 47 months (range 11-138). In six patients, regardless of the administration of chemotherapy, the tumor either spontaneously differentiated toward mature glia or increased in volume, mimicking progression but still remaining completely mature. Five of six patients wishing to procreate had a total of seven normal pregnancies.Pure ovarian immature teratoma is a potentially curable disease with a unique natural history. Our data substantiate the hypothesis that low-grade and low-stage tumors do not require chemotherapy, and that a fertility-sparing surgical approach is warranted in all cases." @default.
- W201715397 created "2016-06-24" @default.
- W201715397 creator A5006144860 @default.
- W201715397 creator A5039966143 @default.
- W201715397 creator A5052283738 @default.
- W201715397 creator A5057586511 @default.
- W201715397 creator A5066888430 @default.
- W201715397 creator A5071623761 @default.
- W201715397 date "1994-10-01" @default.
- W201715397 modified "2023-09-27" @default.
- W201715397 title "Pure ovarian immature teratoma, a unique and curable disease: 10 years' experience of 32 prospectively treated patients." @default.
- W201715397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7522313" @default.
- W201715397 hasPublicationYear "1994" @default.
- W201715397 type Work @default.
- W201715397 sameAs 201715397 @default.
- W201715397 citedByCount "34" @default.
- W201715397 countsByYear W2017153972012 @default.
- W201715397 countsByYear W2017153972013 @default.
- W201715397 countsByYear W2017153972014 @default.
- W201715397 countsByYear W2017153972015 @default.
- W201715397 countsByYear W2017153972016 @default.
- W201715397 countsByYear W2017153972017 @default.
- W201715397 countsByYear W2017153972019 @default.
- W201715397 countsByYear W2017153972022 @default.
- W201715397 countsByYear W2017153972023 @default.
- W201715397 crossrefType "journal-article" @default.
- W201715397 hasAuthorship W201715397A5006144860 @default.
- W201715397 hasAuthorship W201715397A5039966143 @default.
- W201715397 hasAuthorship W201715397A5052283738 @default.
- W201715397 hasAuthorship W201715397A5057586511 @default.
- W201715397 hasAuthorship W201715397A5066888430 @default.
- W201715397 hasAuthorship W201715397A5071623761 @default.
- W201715397 hasConcept C141071460 @default.
- W201715397 hasConcept C146357865 @default.
- W201715397 hasConcept C151730666 @default.
- W201715397 hasConcept C2776057878 @default.
- W201715397 hasConcept C2776694085 @default.
- W201715397 hasConcept C2776938808 @default.
- W201715397 hasConcept C2778889167 @default.
- W201715397 hasConcept C2908647359 @default.
- W201715397 hasConcept C71924100 @default.
- W201715397 hasConcept C86803240 @default.
- W201715397 hasConcept C99454951 @default.
- W201715397 hasConceptScore W201715397C141071460 @default.
- W201715397 hasConceptScore W201715397C146357865 @default.
- W201715397 hasConceptScore W201715397C151730666 @default.
- W201715397 hasConceptScore W201715397C2776057878 @default.
- W201715397 hasConceptScore W201715397C2776694085 @default.
- W201715397 hasConceptScore W201715397C2776938808 @default.
- W201715397 hasConceptScore W201715397C2778889167 @default.
- W201715397 hasConceptScore W201715397C2908647359 @default.
- W201715397 hasConceptScore W201715397C71924100 @default.
- W201715397 hasConceptScore W201715397C86803240 @default.
- W201715397 hasConceptScore W201715397C99454951 @default.
- W201715397 hasIssue "4" @default.
- W201715397 hasLocation W2017153971 @default.
- W201715397 hasOpenAccess W201715397 @default.
- W201715397 hasPrimaryLocation W2017153971 @default.
- W201715397 hasRelatedWork W1992961580 @default.
- W201715397 hasRelatedWork W2024772714 @default.
- W201715397 hasRelatedWork W2024992788 @default.
- W201715397 hasRelatedWork W2028355054 @default.
- W201715397 hasRelatedWork W2062851047 @default.
- W201715397 hasRelatedWork W2076409326 @default.
- W201715397 hasRelatedWork W2080252110 @default.
- W201715397 hasRelatedWork W2412313517 @default.
- W201715397 hasRelatedWork W280502599 @default.
- W201715397 hasRelatedWork W3163965588 @default.
- W201715397 hasVolume "84" @default.
- W201715397 isParatext "false" @default.
- W201715397 isRetracted "false" @default.
- W201715397 magId "201715397" @default.
- W201715397 workType "article" @default.