Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017156876> ?p ?o ?g. }
- W2017156876 endingPage "2244" @default.
- W2017156876 startingPage "2232" @default.
- W2017156876 abstract "A series of N-10 urea derivatives of phenothiazine was synthesized and each compound was evaluated for its ability to inhibit human cholinesterases. Most were specific inhibitors of BuChE. However, the potent inhibitory effects on both cholinesterases of one sub-class, the cationic aminoureas, provide an additional binding mechanism to cholinesterases for these compounds. The comparative effects of aminoureas on wild-type BuChE and several BuChE mutants indicate a binding process involving salt linkage with the aspartate of the cholinesterase peripheral anionic site. The effect of such compounds on cholinesterase activity at high substrate concentration supports ionic interaction of aminoureas at the peripheral anionic site." @default.
- W2017156876 created "2016-06-24" @default.
- W2017156876 creator A5008278069 @default.
- W2017156876 creator A5018130591 @default.
- W2017156876 creator A5046618540 @default.
- W2017156876 creator A5047406282 @default.
- W2017156876 creator A5048819985 @default.
- W2017156876 creator A5059716124 @default.
- W2017156876 creator A5063159438 @default.
- W2017156876 creator A5074696581 @default.
- W2017156876 creator A5080647361 @default.
- W2017156876 date "2010-03-01" @default.
- W2017156876 modified "2023-09-30" @default.
- W2017156876 title "Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants" @default.
- W2017156876 cites W1561647671 @default.
- W2017156876 cites W1966680575 @default.
- W2017156876 cites W1968425023 @default.
- W2017156876 cites W1969690495 @default.
- W2017156876 cites W1971048984 @default.
- W2017156876 cites W1980803538 @default.
- W2017156876 cites W1982064952 @default.
- W2017156876 cites W1984314839 @default.
- W2017156876 cites W1994067502 @default.
- W2017156876 cites W2001535569 @default.
- W2017156876 cites W2011000826 @default.
- W2017156876 cites W2015389516 @default.
- W2017156876 cites W2021280501 @default.
- W2017156876 cites W2024623973 @default.
- W2017156876 cites W2036349073 @default.
- W2017156876 cites W2041685043 @default.
- W2017156876 cites W2049955167 @default.
- W2017156876 cites W2050668497 @default.
- W2017156876 cites W2056737480 @default.
- W2017156876 cites W2068950612 @default.
- W2017156876 cites W2070566742 @default.
- W2017156876 cites W2072688677 @default.
- W2017156876 cites W2073436941 @default.
- W2017156876 cites W2074722271 @default.
- W2017156876 cites W2076166567 @default.
- W2017156876 cites W2077328797 @default.
- W2017156876 cites W2081058092 @default.
- W2017156876 cites W2086916510 @default.
- W2017156876 cites W2098437204 @default.
- W2017156876 cites W2111863354 @default.
- W2017156876 cites W2122429894 @default.
- W2017156876 cites W2130479394 @default.
- W2017156876 cites W2136995362 @default.
- W2017156876 cites W2140037470 @default.
- W2017156876 cites W2143410390 @default.
- W2017156876 cites W2159866533 @default.
- W2017156876 cites W2316650519 @default.
- W2017156876 cites W2322901654 @default.
- W2017156876 cites W4232095420 @default.
- W2017156876 doi "https://doi.org/10.1016/j.bmc.2010.01.066" @default.
- W2017156876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20181484" @default.
- W2017156876 hasPublicationYear "2010" @default.
- W2017156876 type Work @default.
- W2017156876 sameAs 2017156876 @default.
- W2017156876 citedByCount "32" @default.
- W2017156876 countsByYear W20171568762012 @default.
- W2017156876 countsByYear W20171568762013 @default.
- W2017156876 countsByYear W20171568762014 @default.
- W2017156876 countsByYear W20171568762015 @default.
- W2017156876 countsByYear W20171568762016 @default.
- W2017156876 countsByYear W20171568762017 @default.
- W2017156876 countsByYear W20171568762018 @default.
- W2017156876 countsByYear W20171568762019 @default.
- W2017156876 countsByYear W20171568762020 @default.
- W2017156876 countsByYear W20171568762021 @default.
- W2017156876 countsByYear W20171568762022 @default.
- W2017156876 countsByYear W20171568762023 @default.
- W2017156876 crossrefType "journal-article" @default.
- W2017156876 hasAuthorship W2017156876A5008278069 @default.
- W2017156876 hasAuthorship W2017156876A5018130591 @default.
- W2017156876 hasAuthorship W2017156876A5046618540 @default.
- W2017156876 hasAuthorship W2017156876A5047406282 @default.
- W2017156876 hasAuthorship W2017156876A5048819985 @default.
- W2017156876 hasAuthorship W2017156876A5059716124 @default.
- W2017156876 hasAuthorship W2017156876A5063159438 @default.
- W2017156876 hasAuthorship W2017156876A5074696581 @default.
- W2017156876 hasAuthorship W2017156876A5080647361 @default.
- W2017156876 hasConcept C104317684 @default.
- W2017156876 hasConcept C107824862 @default.
- W2017156876 hasConcept C143065580 @default.
- W2017156876 hasConcept C181199279 @default.
- W2017156876 hasConcept C185592680 @default.
- W2017156876 hasConcept C2778716775 @default.
- W2017156876 hasConcept C2778816929 @default.
- W2017156876 hasConcept C2779059548 @default.
- W2017156876 hasConcept C2779101902 @default.
- W2017156876 hasConcept C31896038 @default.
- W2017156876 hasConcept C55493867 @default.
- W2017156876 hasConcept C71240020 @default.
- W2017156876 hasConcept C71924100 @default.
- W2017156876 hasConcept C98274493 @default.
- W2017156876 hasConceptScore W2017156876C104317684 @default.
- W2017156876 hasConceptScore W2017156876C107824862 @default.
- W2017156876 hasConceptScore W2017156876C143065580 @default.