Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017162336> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2017162336 endingPage "32" @default.
- W2017162336 startingPage "23" @default.
- W2017162336 abstract "Studies with an insitu preparation of guinea pig uterus suggest the possible involvement of the lipoxygenase pathway of arachidonic acid (AA) metabolism in myometrial contractions. Female guinea pigs were sensitized to ovalbumin (OA) on day one of their estrous cycle. On day 14, these pigs were anesthetized and the uterus was cannulated for measuring contractions. OA challenge, with histamine antagonism (methpyrilene) resulted in utering contractions which significantly raised myometrial tonus, presumably due to AA metabolites. Pretreatment with high doses of indomethacin resulted. in only 60% inhibition of the OA induced contraction, suggesting the remaining contraction was due to something other than cyclooxygenase products. In the presence of indomethacin and methapyrilene, the addition of AA to increase available substrate caused increased myometrial tone following antigen challenge. This increase in uterine tone was inhibited in a dose dependent fashion by FPL-55712 demonstrating that leukotrienes can contract the uterus and that antigen challenge may provide a means for studying leukotriene involvement in uterine pathophysiology." @default.
- W2017162336 created "2016-06-24" @default.
- W2017162336 creator A5002355857 @default.
- W2017162336 creator A5003656497 @default.
- W2017162336 creator A5036612527 @default.
- W2017162336 creator A5063573332 @default.
- W2017162336 date "1983-07-01" @default.
- W2017162336 modified "2023-09-27" @default.
- W2017162336 title "Involvement of lipoxygenase products in myometrial contractions" @default.
- W2017162336 cites W1989028499 @default.
- W2017162336 cites W1993589319 @default.
- W2017162336 cites W1994896371 @default.
- W2017162336 cites W2009270426 @default.
- W2017162336 cites W2015123370 @default.
- W2017162336 cites W2056437623 @default.
- W2017162336 cites W2062626394 @default.
- W2017162336 cites W2068503311 @default.
- W2017162336 cites W2083717098 @default.
- W2017162336 cites W2089365555 @default.
- W2017162336 doi "https://doi.org/10.1016/0090-6980(83)90071-0" @default.
- W2017162336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6415759" @default.
- W2017162336 hasPublicationYear "1983" @default.
- W2017162336 type Work @default.
- W2017162336 sameAs 2017162336 @default.
- W2017162336 citedByCount "69" @default.
- W2017162336 countsByYear W20171623362016 @default.
- W2017162336 countsByYear W20171623362017 @default.
- W2017162336 countsByYear W20171623362021 @default.
- W2017162336 crossrefType "journal-article" @default.
- W2017162336 hasAuthorship W2017162336A5002355857 @default.
- W2017162336 hasAuthorship W2017162336A5003656497 @default.
- W2017162336 hasAuthorship W2017162336A5036612527 @default.
- W2017162336 hasAuthorship W2017162336A5063573332 @default.
- W2017162336 hasConcept C1122143 @default.
- W2017162336 hasConcept C126322002 @default.
- W2017162336 hasConcept C134018914 @default.
- W2017162336 hasConcept C147483822 @default.
- W2017162336 hasConcept C163415756 @default.
- W2017162336 hasConcept C181199279 @default.
- W2017162336 hasConcept C185592680 @default.
- W2017162336 hasConcept C1998276 @default.
- W2017162336 hasConcept C203014093 @default.
- W2017162336 hasConcept C2776042228 @default.
- W2017162336 hasConcept C2776452501 @default.
- W2017162336 hasConcept C2776766599 @default.
- W2017162336 hasConcept C2776946954 @default.
- W2017162336 hasConcept C2778078955 @default.
- W2017162336 hasConcept C2778815084 @default.
- W2017162336 hasConcept C2779066055 @default.
- W2017162336 hasConcept C2779689624 @default.
- W2017162336 hasConcept C2780857362 @default.
- W2017162336 hasConcept C55493867 @default.
- W2017162336 hasConcept C71924100 @default.
- W2017162336 hasConcept C86803240 @default.
- W2017162336 hasConceptScore W2017162336C1122143 @default.
- W2017162336 hasConceptScore W2017162336C126322002 @default.
- W2017162336 hasConceptScore W2017162336C134018914 @default.
- W2017162336 hasConceptScore W2017162336C147483822 @default.
- W2017162336 hasConceptScore W2017162336C163415756 @default.
- W2017162336 hasConceptScore W2017162336C181199279 @default.
- W2017162336 hasConceptScore W2017162336C185592680 @default.
- W2017162336 hasConceptScore W2017162336C1998276 @default.
- W2017162336 hasConceptScore W2017162336C203014093 @default.
- W2017162336 hasConceptScore W2017162336C2776042228 @default.
- W2017162336 hasConceptScore W2017162336C2776452501 @default.
- W2017162336 hasConceptScore W2017162336C2776766599 @default.
- W2017162336 hasConceptScore W2017162336C2776946954 @default.
- W2017162336 hasConceptScore W2017162336C2778078955 @default.
- W2017162336 hasConceptScore W2017162336C2778815084 @default.
- W2017162336 hasConceptScore W2017162336C2779066055 @default.
- W2017162336 hasConceptScore W2017162336C2779689624 @default.
- W2017162336 hasConceptScore W2017162336C2780857362 @default.
- W2017162336 hasConceptScore W2017162336C55493867 @default.
- W2017162336 hasConceptScore W2017162336C71924100 @default.
- W2017162336 hasConceptScore W2017162336C86803240 @default.
- W2017162336 hasIssue "1" @default.
- W2017162336 hasLocation W20171623361 @default.
- W2017162336 hasLocation W20171623362 @default.
- W2017162336 hasOpenAccess W2017162336 @default.
- W2017162336 hasPrimaryLocation W20171623361 @default.
- W2017162336 hasRelatedWork W1990941836 @default.
- W2017162336 hasRelatedWork W2009454127 @default.
- W2017162336 hasRelatedWork W2012330107 @default.
- W2017162336 hasRelatedWork W2017162336 @default.
- W2017162336 hasRelatedWork W2032909886 @default.
- W2017162336 hasRelatedWork W2053929890 @default.
- W2017162336 hasRelatedWork W2091479157 @default.
- W2017162336 hasRelatedWork W2416992496 @default.
- W2017162336 hasRelatedWork W749575873 @default.
- W2017162336 hasRelatedWork W1966024763 @default.
- W2017162336 hasVolume "26" @default.
- W2017162336 isParatext "false" @default.
- W2017162336 isRetracted "false" @default.
- W2017162336 magId "2017162336" @default.
- W2017162336 workType "article" @default.