FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017168220> ?p ?o ?g. }

• W2017168220 endingPage "7386" @default.
• W2017168220 startingPage "7373" @default.
• W2017168220 abstract "Lateral diffusion of membrane components makes possible any in-plane membrane reaction and has a key role in signaling in cell membranes. In this report the equilibrium lateral diffusion of intrinsic molecules in an equimolar DMPC/DSPC mixture is simulated using a thoroughly tested two-state model of two-component phospholipid bilayers. The model has been successful in calculating the excess heat capacity function, the most frequent center-to-center distances between DSPC clusters, and the fractal dimensions of gel clusters (Sugar, I. P., Thompson, T. E., Biltonen, R. L. Biophys. J. 1999, 76, 2099-2110). In the gel/fluid mixed phase region, a diffusing intrinsic molecule may change its state from fluid to gel (or from gel to fluid) at any time. A common characterization of the diffusion of intrinsic molecules is given by the simulated average first-passage time curves. We find that these curves can be described as power functions containing two parameters, alpha and beta, except near the percolation threshold of gel/fluid or compositional clusters. We find also that the intrinsic molecules are involved in approximately normal diffusion, i.e., beta approximately 2 in the extreme gel and fluid phase regions, while in the gel/fluid and gel/gel mixed phase regions the diffusion is anomalous, i.e., beta not equal 2. In the mixed phase regions, when the initial local state of the diffusing molecule is not specified, each component is involved in sub-diffusion (beta > 2). In the gel/fluid mixed phase region molecules situated initially inside a fluid cluster are involved in sub-diffusion, but DMPC molecules situated initially inside a gel cluster are involved in super-diffusion (beta < 2). The possibility of anomalous diffusion in membranes apparently arises because the diffusing molecule visits a variety of different environments characterized by its relative proximity to various membrane components. The diffusion is actually anomalous when the components of the bilayer are nonrandomly distributed. The deviation from random distribution is strongly correlated with beta. Similar to the results of the NMR experiments, the calculated relative diffusion coefficient continuously decreases in the gel/fluid mixed phase region with decreasing temperature. In apparent contradiction, diffusion measured by fluorescence recovery after photobleaching (FRAP) demonstrates the existence of a threshold temperature, below which long-range diffusion of FRAP probe molecules is essentially blocked. This threshold temperature is highly correlated with the percolation temperature of gel clusters." @default.
• W2017168220 created "2016-06-24" @default.
• W2017168220 creator A5078777363 @default.
• W2017168220 creator A5082696850 @default.
• W2017168220 date "2005-03-23" @default.
• W2017168220 modified "2023-09-23" @default.
• W2017168220 title "Lateral Diffusion of Molecules in Two-Component Lipid Bilayer: A Monte Carlo Simulation Study" @default.
• W2017168220 cites W1562912280 @default.
• W2017168220 cites W1564861448 @default.
• W2017168220 cites W1566113502 @default.
• W2017168220 cites W1666553655 @default.
• W2017168220 cites W1964922782 @default.
• W2017168220 cites W1965398681 @default.
• W2017168220 cites W1966728800 @default.
• W2017168220 cites W1967070213 @default.
• W2017168220 cites W1975673009 @default.
• W2017168220 cites W1987712666 @default.
• W2017168220 cites W1996016803 @default.
• W2017168220 cites W2004925910 @default.
• W2017168220 cites W2008940139 @default.
• W2017168220 cites W2014710787 @default.
• W2017168220 cites W2018419210 @default.
• W2017168220 cites W2022475320 @default.
• W2017168220 cites W2031131231 @default.
• W2017168220 cites W2031780400 @default.
• W2017168220 cites W2039190086 @default.
• W2017168220 cites W2042774477 @default.
• W2017168220 cites W2046151563 @default.
• W2017168220 cites W2047343299 @default.
• W2017168220 cites W2048072189 @default.
• W2017168220 cites W2050627545 @default.
• W2017168220 cites W2056760934 @default.
• W2017168220 cites W2067343536 @default.
• W2017168220 cites W2067861749 @default.
• W2017168220 cites W2073654568 @default.
• W2017168220 cites W2079641905 @default.
• W2017168220 cites W2082193692 @default.
• W2017168220 cites W2085843372 @default.
• W2017168220 cites W2094875314 @default.
• W2017168220 cites W2108461844 @default.
• W2017168220 cites W2132885923 @default.
• W2017168220 cites W2136864234 @default.
• W2017168220 cites W2147688960 @default.
• W2017168220 cites W2180329483 @default.
• W2017168220 cites W3004463191 @default.
• W2017168220 cites W4238026114 @default.
• W2017168220 doi "https://doi.org/10.1021/jp045669x" @default.
• W2017168220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16851844" @default.
• W2017168220 hasPublicationYear "2005" @default.
• W2017168220 type Work @default.
• W2017168220 sameAs 2017168220 @default.
• W2017168220 citedByCount "18" @default.
• W2017168220 countsByYear W20171682202012 @default.
• W2017168220 countsByYear W20171682202013 @default.
• W2017168220 countsByYear W20171682202021 @default.
• W2017168220 countsByYear W20171682202022 @default.
• W2017168220 crossrefType "journal-article" @default.
• W2017168220 hasAuthorship W2017168220A5078777363 @default.
• W2017168220 hasAuthorship W2017168220A5082696850 @default.
• W2017168220 hasConcept C121332964 @default.
• W2017168220 hasConcept C159467904 @default.
• W2017168220 hasConcept C162324750 @default.
• W2017168220 hasConcept C169760540 @default.
• W2017168220 hasConcept C176217482 @default.
• W2017168220 hasConcept C178790620 @default.
• W2017168220 hasConcept C185592680 @default.
• W2017168220 hasConcept C192157962 @default.
• W2017168220 hasConcept C21547014 @default.
• W2017168220 hasConcept C2780457167 @default.
• W2017168220 hasConcept C32909587 @default.
• W2017168220 hasConcept C41625074 @default.
• W2017168220 hasConcept C44280652 @default.
• W2017168220 hasConcept C55493867 @default.
• W2017168220 hasConcept C57736034 @default.
• W2017168220 hasConcept C69357855 @default.
• W2017168220 hasConcept C86803240 @default.
• W2017168220 hasConcept C97355855 @default.
• W2017168220 hasConceptScore W2017168220C121332964 @default.
• W2017168220 hasConceptScore W2017168220C159467904 @default.
• W2017168220 hasConceptScore W2017168220C162324750 @default.
• W2017168220 hasConceptScore W2017168220C169760540 @default.
• W2017168220 hasConceptScore W2017168220C176217482 @default.
• W2017168220 hasConceptScore W2017168220C178790620 @default.
• W2017168220 hasConceptScore W2017168220C185592680 @default.
• W2017168220 hasConceptScore W2017168220C192157962 @default.
• W2017168220 hasConceptScore W2017168220C21547014 @default.
• W2017168220 hasConceptScore W2017168220C2780457167 @default.
• W2017168220 hasConceptScore W2017168220C32909587 @default.
• W2017168220 hasConceptScore W2017168220C41625074 @default.
• W2017168220 hasConceptScore W2017168220C44280652 @default.
• W2017168220 hasConceptScore W2017168220C55493867 @default.
• W2017168220 hasConceptScore W2017168220C57736034 @default.
• W2017168220 hasConceptScore W2017168220C69357855 @default.
• W2017168220 hasConceptScore W2017168220C86803240 @default.
• W2017168220 hasConceptScore W2017168220C97355855 @default.
• W2017168220 hasIssue "15" @default.
• W2017168220 hasLocation W20171682201 @default.
• W2017168220 hasLocation W20171682202 @default.

• next