Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017168464> ?p ?o ?g. }
- W2017168464 endingPage "382" @default.
- W2017168464 startingPage "375" @default.
- W2017168464 abstract "Summary At the University Hospital of Cologne, in general two patient groups at high risk for invasive aspergillosis receive posaconazole prophylaxis: Acute myelogenous leukaemia patients during remission induction chemotherapy and allogeneic haematopoietic stem cell transplant recipients. Other patients at risk undergo serum galactomannan testing three times weekly. At 72–96 h of persisting fever despite broad‐spectrum antibiotics, or at onset of lower respiratory tract symptoms a thoracic computed tomography ( CT ) scan is performed. Without lung infiltrates on CT , IPA is ruled out. In lung infiltrates not suggestive for IPA mycological confirmation is pursued. In patients without posaconazole prophylaxis empiric caspofungin will be considered. CT findings typical for IPA prompt targeted treatment, and mycological confirmation. Bronchoalveolar lavage ( BAL ) is most important for cultural identification and susceptibility testing, and facilitates diagnosing other pathogens. BAL performance is virtually independent of platelet counts. If despite suggestive infiltrates BAL does not yield the diagnosis, CT ‐guided biopsy follows as soon as platelet counts allow. Surgery can also be beneficial in diagnosis and treatment of IPA . If the diagnosis of IPA is not established, mucormycosis is a valid concern. In patients with breakthrough IPA during posaconazole prophylaxis liposomal amphotericin B is the drug of choice. If no posaconazole prophylaxis was given, voriconazole is the treatment of choice for IPA ." @default.
- W2017168464 created "2016-06-24" @default.
- W2017168464 creator A5011314849 @default.
- W2017168464 creator A5019676489 @default.
- W2017168464 creator A5031047370 @default.
- W2017168464 creator A5032425560 @default.
- W2017168464 creator A5037775556 @default.
- W2017168464 creator A5041454251 @default.
- W2017168464 creator A5045495880 @default.
- W2017168464 creator A5070655188 @default.
- W2017168464 creator A5071003935 @default.
- W2017168464 creator A5071543445 @default.
- W2017168464 creator A5072517213 @default.
- W2017168464 creator A5075139311 @default.
- W2017168464 creator A5087860754 @default.
- W2017168464 date "2015-03-24" @default.
- W2017168464 modified "2023-10-03" @default.
- W2017168464 title "Our 2015 approach to invasive pulmonary aspergillosis" @default.
- W2017168464 cites W1509263278 @default.
- W2017168464 cites W1510361106 @default.
- W2017168464 cites W1572853853 @default.
- W2017168464 cites W1605806048 @default.
- W2017168464 cites W1721325880 @default.
- W2017168464 cites W1804118339 @default.
- W2017168464 cites W1830835745 @default.
- W2017168464 cites W1884126821 @default.
- W2017168464 cites W1963782245 @default.
- W2017168464 cites W1966092471 @default.
- W2017168464 cites W1969476450 @default.
- W2017168464 cites W1972502019 @default.
- W2017168464 cites W1973430218 @default.
- W2017168464 cites W1976590438 @default.
- W2017168464 cites W1977819832 @default.
- W2017168464 cites W1981148437 @default.
- W2017168464 cites W1982405193 @default.
- W2017168464 cites W1988385266 @default.
- W2017168464 cites W1989345554 @default.
- W2017168464 cites W1989723363 @default.
- W2017168464 cites W1990648853 @default.
- W2017168464 cites W1997382007 @default.
- W2017168464 cites W2000500424 @default.
- W2017168464 cites W2014582252 @default.
- W2017168464 cites W2018771059 @default.
- W2017168464 cites W2020754496 @default.
- W2017168464 cites W2021841870 @default.
- W2017168464 cites W2023843703 @default.
- W2017168464 cites W2025830701 @default.
- W2017168464 cites W2029565940 @default.
- W2017168464 cites W2029714817 @default.
- W2017168464 cites W2039267791 @default.
- W2017168464 cites W2039458277 @default.
- W2017168464 cites W2040405627 @default.
- W2017168464 cites W2044241248 @default.
- W2017168464 cites W2044265242 @default.
- W2017168464 cites W2050009047 @default.
- W2017168464 cites W2059048036 @default.
- W2017168464 cites W2061438827 @default.
- W2017168464 cites W2069634678 @default.
- W2017168464 cites W2070395634 @default.
- W2017168464 cites W2079143027 @default.
- W2017168464 cites W2084087805 @default.
- W2017168464 cites W2087796927 @default.
- W2017168464 cites W2097394217 @default.
- W2017168464 cites W2097950056 @default.
- W2017168464 cites W2101541076 @default.
- W2017168464 cites W2104839821 @default.
- W2017168464 cites W2105011956 @default.
- W2017168464 cites W2106895832 @default.
- W2017168464 cites W2108791013 @default.
- W2017168464 cites W2116241030 @default.
- W2017168464 cites W2116440163 @default.
- W2017168464 cites W2120523595 @default.
- W2017168464 cites W2123134253 @default.
- W2017168464 cites W2123708935 @default.
- W2017168464 cites W2126301671 @default.
- W2017168464 cites W2126516337 @default.
- W2017168464 cites W2128856844 @default.
- W2017168464 cites W2130180365 @default.
- W2017168464 cites W2131994909 @default.
- W2017168464 cites W2133380024 @default.
- W2017168464 cites W2135290759 @default.
- W2017168464 cites W2138585965 @default.
- W2017168464 cites W2141436450 @default.
- W2017168464 cites W2143021589 @default.
- W2017168464 cites W2148325123 @default.
- W2017168464 cites W2150470213 @default.
- W2017168464 cites W2150824761 @default.
- W2017168464 cites W2151209623 @default.
- W2017168464 cites W2151254250 @default.
- W2017168464 cites W2153420155 @default.
- W2017168464 cites W2154955932 @default.
- W2017168464 cites W2156038438 @default.
- W2017168464 cites W2156839860 @default.
- W2017168464 cites W2158382206 @default.
- W2017168464 cites W2158597663 @default.
- W2017168464 cites W2160615860 @default.
- W2017168464 cites W2161908501 @default.
- W2017168464 cites W2163773890 @default.