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- W2017168728 abstract "THE intravenous injection of a large dose of thyroxine is followed by increased biliary excretion of iodine (Kendall, 1919), and by the excretion of thyroxine in the feces (Gross and LeBlond, 1947, Monroe and Turner, 1948). However, only a small per cent of the injected thyroxine is excreted in the bile (Gross and LeBlond, 1947, Monroe and Turner, 1948). For one hour after thyroxine is injected intravenously the hormone is excreted in the bile unchanged. Thereafter the injected thyroxine is eliminated in the bile as an unknown compound (Taurog, Briggs and Chaikoff, 1951). This unknown compound is hydrolyzed during its passage through the gut, and releases free thyroxine which is not absorbed (Taurog, Briggs and Chaikoff, 1952). When physiological doses of thyroxine are injected, the percentage fixed by the liver and excreted in the feces is even smaller (LeBlond, 1949). It has been shown previously that transplanted thyroid tissue functions in the same manner as does the thyroid in its normal position as ..." @default.
- W2017168728 created "2016-06-24" @default.
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- W2017168728 date "1952-10-01" @default.
- W2017168728 modified "2023-09-27" @default.
- W2017168728 title "ACTION OF LIVER ON THYROID HORMONE FOLLOWING INTRASPLENIC IMPLANTATION OF THE THYROID" @default.
- W2017168728 doi "https://doi.org/10.1210/endo-51-4-306" @default.
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