FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017174148> ?p ?o ?g. }

• W2017174148 endingPage "c114" @default.
• W2017174148 startingPage "c108" @default.
• W2017174148 abstract "<i>Background:</i> The intact parathyroid hormone (PTH) assay detects both PTH(1–84) and the PTH(7–84)-like fragment, which is reported to be an antagonist of the biological action of PTH(1–84). It is debatable which of the two assays is clinically more useful, the intact or bio-PTH assay, the latter of which only detects PTH(1–84). It is also unknown whether serum levels of the PTH(7–84)-like fragment have clinical significance. <i>Methods:</i> Serum PTH concentrations in 104 predialysis patients with chronic renal failure (CRF; serum creatinine 3.53 ± 1.93; 62 males and 42 females; 61.0 ± 11.5 years old) were measured using both the intact and bio-PTH assays, and the concentration of the PTH(7–84)-like fragment was calculated by subtracting bio-PTH from intact PTH. Three bone formation and three bone resorption markers were measured simultaneously. <i>Results:</i> The PTH values measured using the two assays were strongly positively correlated (r = 0.959, p < 0.0001), and were also significantly positively correlated with the three bone formation and three bone resorption markers to a similar degree. The PTH(7–84)-like fragment was significantly positively correlated with both the intact and bio-PTH (r = 0.855, p < 0.0001 for intact PTH; r = 0.672, p < 0.0001 for bio-PTH), and was also significantly positively correlated with each of the six bone metabolism markers. There is no significant relationship between the bio-PTH/PTH(7–84)-like fragment ratio and clinical parameters including bone metabolic markers. <i>Conclusion:</i> From the strong relationship between the two assays, and the similar degree of the relationship between each PTH assay and each of the six bone metabolism markers, it is considered that the bio-PTH and intact PTH assays have similar clinical significance in predialysis CRF patients. Serum levels of the PTH(7–84)-like fragment seem to increase as serum PTH(1–84) increases. The results suggest that the serum PTH(7–84)-like fragment has little specific clinical effect on bone metabolism, even when assessed by the ratio of bio-PTH/PTH(7–84)-like fragment." @default.
• W2017174148 created "2016-06-24" @default.
• W2017174148 creator A5031499140 @default.
• W2017174148 creator A5035157397 @default.
• W2017174148 creator A5036265037 @default.
• W2017174148 creator A5049510620 @default.
• W2017174148 creator A5062703256 @default.
• W2017174148 creator A5067176715 @default.
• W2017174148 creator A5072873359 @default.
• W2017174148 creator A5079695159 @default.
• W2017174148 creator A5081474992 @default.
• W2017174148 date "2005-11-15" @default.
• W2017174148 modified "2023-09-25" @default.
• W2017174148 title "Serum Levels of 1–84 and 7–84 Parathyroid Hormone in Predialysis Patients with Chronic Renal Failure Measured by the Intact and Bio-PTH Assay" @default.
• W2017174148 cites W1607276167 @default.
• W2017174148 cites W1673591261 @default.
• W2017174148 cites W1922554536 @default.
• W2017174148 cites W194637465 @default.
• W2017174148 cites W1964403552 @default.
• W2017174148 cites W1975162867 @default.
• W2017174148 cites W1976477636 @default.
• W2017174148 cites W1986613052 @default.
• W2017174148 cites W1994044840 @default.
• W2017174148 cites W1998072089 @default.
• W2017174148 cites W2018901319 @default.
• W2017174148 cites W2039435952 @default.
• W2017174148 cites W2040437189 @default.
• W2017174148 cites W2065315722 @default.
• W2017174148 cites W2067704553 @default.
• W2017174148 cites W2067753153 @default.
• W2017174148 cites W2069627659 @default.
• W2017174148 cites W2086421534 @default.
• W2017174148 cites W2092374806 @default.
• W2017174148 cites W2096414829 @default.
• W2017174148 cites W2100792139 @default.
• W2017174148 cites W2105853087 @default.
• W2017174148 cites W2107094270 @default.
• W2017174148 cites W2112729869 @default.
• W2017174148 cites W2121187809 @default.
• W2017174148 cites W2122172605 @default.
• W2017174148 cites W2124967376 @default.
• W2017174148 cites W2133512897 @default.
• W2017174148 cites W2156064175 @default.
• W2017174148 cites W2162385374 @default.
• W2017174148 cites W2163995267 @default.
• W2017174148 cites W2168154455 @default.
• W2017174148 cites W2323039749 @default.
• W2017174148 cites W2387480025 @default.
• W2017174148 cites W2548549197 @default.
• W2017174148 doi "https://doi.org/10.1159/000089668" @default.
• W2017174148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16286785" @default.
• W2017174148 hasPublicationYear "2005" @default.
• W2017174148 type Work @default.
• W2017174148 sameAs 2017174148 @default.
• W2017174148 citedByCount "8" @default.
• W2017174148 countsByYear W20171741482016 @default.
• W2017174148 countsByYear W20171741482020 @default.
• W2017174148 countsByYear W20171741482022 @default.
• W2017174148 crossrefType "journal-article" @default.
• W2017174148 hasAuthorship W2017174148A5031499140 @default.
• W2017174148 hasAuthorship W2017174148A5035157397 @default.
• W2017174148 hasAuthorship W2017174148A5036265037 @default.
• W2017174148 hasAuthorship W2017174148A5049510620 @default.
• W2017174148 hasAuthorship W2017174148A5062703256 @default.
• W2017174148 hasAuthorship W2017174148A5067176715 @default.
• W2017174148 hasAuthorship W2017174148A5072873359 @default.
• W2017174148 hasAuthorship W2017174148A5079695159 @default.
• W2017174148 hasAuthorship W2017174148A5081474992 @default.
• W2017174148 hasConcept C126322002 @default.
• W2017174148 hasConcept C134018914 @default.
• W2017174148 hasConcept C146562846 @default.
• W2017174148 hasConcept C170033053 @default.
• W2017174148 hasConcept C176685330 @default.
• W2017174148 hasConcept C2780306776 @default.
• W2017174148 hasConcept C2781208988 @default.
• W2017174148 hasConcept C519063684 @default.
• W2017174148 hasConcept C673006 @default.
• W2017174148 hasConcept C71924100 @default.
• W2017174148 hasConceptScore W2017174148C126322002 @default.
• W2017174148 hasConceptScore W2017174148C134018914 @default.
• W2017174148 hasConceptScore W2017174148C146562846 @default.
• W2017174148 hasConceptScore W2017174148C170033053 @default.
• W2017174148 hasConceptScore W2017174148C176685330 @default.
• W2017174148 hasConceptScore W2017174148C2780306776 @default.
• W2017174148 hasConceptScore W2017174148C2781208988 @default.
• W2017174148 hasConceptScore W2017174148C519063684 @default.
• W2017174148 hasConceptScore W2017174148C673006 @default.
• W2017174148 hasConceptScore W2017174148C71924100 @default.
• W2017174148 hasIssue "3-4" @default.
• W2017174148 hasLocation W20171741481 @default.
• W2017174148 hasLocation W20171741482 @default.
• W2017174148 hasOpenAccess W2017174148 @default.
• W2017174148 hasPrimaryLocation W20171741481 @default.
• W2017174148 hasRelatedWork W1967422973 @default.
• W2017174148 hasRelatedWork W1990422519 @default.
• W2017174148 hasRelatedWork W2036148628 @default.
• W2017174148 hasRelatedWork W2041938128 @default.
• W2017174148 hasRelatedWork W2053638911 @default.

• next