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• W2017174554 abstract "Recombinant protein polymers, evaluated exten-sively as biomaterials for applications in drug delivery and tissue engineering, are rarely reported as being optically transparent. Here we report the notable optical transparency of films composed of a genetically engineered silk-elastinlike protein polymer SELP-47K. SELP-47K films of 100 μm in thickness display a transmittance of 93% in the wavelength range of 350−800 nm. While covalent cross-linking of SELP-47K via glutaraldehyde decreases its transmittance to 77% at the wavelength of 800 nm, noncovalent cross-linking using methanol slightly increases it to 95%. Non- and covalent cross-linking of SELP-47K films also influences their secondary structures and water contents. Cell viability and proliferation analyses further reveal the excellent cytocompatibility of both non- and covalently cross-linked SELP-47K films. The combination of high optical transparency and cytocompatibility of SELP-47K films, together with their previously reported outstanding mechanical properties, suggests that this protein polymer may be useful in unique, new biomedical applications." @default.
• W2017174554 created "2016-06-24" @default.
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• W2017174554 date "2011-02-01" @default.
• W2017174554 modified "2023-09-25" @default.
• W2017174554 title "Optically Transparent Recombinant Silk-Elastinlike Protein Polymer Films" @default.
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• W2017174554 doi "https://doi.org/10.1021/jp109764f" @default.
• W2017174554 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3041846" @default.
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