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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017194866> ?p ?o ?g. }

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• W2017194866 abstract "1-Methyl-4-phenyl-2,3-dihydropyridinium and 1-methyl-4-phenyl-pyridinium species, metabolites of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, non-competitively inhibit glutathione S-transferases of rat brain in vitro. The Ki values for 1-methyl-4-phenyl-2,3-dihydropyridinium bromide and 1-methyl-4-phenyl-pyridinium bromide are 0.67 and 0.3 mM, respectively. Inhibition of these enzymes may lead to impairment of cellular defense mechanisms." @default.
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• W2017194866 date "1987-10-01" @default.
• W2017194866 modified "2023-09-25" @default.
• W2017194866 title "MPTP metabolites inhibit rat brain glutathione S-transferases" @default.
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• W2017194866 doi "https://doi.org/10.1016/0304-3940(87)90358-2" @default.
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