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- W2017199005 abstract "A variety of evidence indicates the presence of a circulating ligand to the Na,K ATPase molecule that is involved in the regulation of extracellular sodium metabolism. To examine the potential role of endogenous ligands to the Na,K ATPase molecule in the regulation of intracellular sodium metabolism, the tissue distribution of digitalis-like activity was quantitated in several brain regions and peripheral organs. The digitalis-like activity of desalted and delipidated extracts of tissue was widely distributed and produced a displacement of tritiated ouabain that was parallel to the displacement produced by cold ouabain. These results suggest that tissue contains an endogenous ligand to the Na,K ATPase molecule and that this ligand may regulate intracellular sodium metabolism in an autocoid-like manner." @default.
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- W2017199005 date "1988-04-01" @default.
- W2017199005 modified "2023-09-25" @default.
- W2017199005 title "Tissue distribution of an endogenous ligand to the NA,K ATPase molecule" @default.
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- W2017199005 doi "https://doi.org/10.1016/s0006-291x(88)80111-6" @default.
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