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• W2017203469 abstract "1. A new method is described for continuous measurement of the cerebral blood flow in the cat. The method employs the registration of the flow from the cannulated superior sagittal sinus after elimination of the main anastomoses between the sinus and extracerebral vessels. 2. The method has been used to study the correlation between cerebral blood flow, EEG and systemic blood pressure under varying experimental conditions such as arousing stimulation, anesthesia, and administration of drugs. 3. The results confirm that an intimate correlation exists between cerebral vasomotor tone and cortical excitatory state as reflected in the EEG. Thus, arousing stimuli which activate the EEG give a marked increase in the cerebral blood flow which is independent of the changes of the systemic blood pressure. Spontaneous changes of flow accompanied by general changes of the EEG have also been observed to occur in the lightly anesthetized animal. 4. Small doses of anesthetic agents, sufficient to induce a sleep pattern of the EEG and a block of the arousal reaction, paralyze the mechanisms regulating cerebral vasomotor tone. In barbiturate anesthesia the cerebral vessels are more constricted than under ether. 5. While confirming earlier findings on cerebral circulation, the results, in addition, demonstrate that the cerebral vascular resistance undergoes larger changes than have previously been shown. The results also throw new light on the importance of autonomic mechanisms for the regulation of sleep and wakefulness." @default.
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• W2017203469 date "1956-08-01" @default.
• W2017203469 modified "2023-10-16" @default.
• W2017203469 title "A new method for measuring cerebral blood flow in relation to the electroencephalogram" @default.
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• W2017203469 doi "https://doi.org/10.1016/0013-4694(56)90005-0" @default.
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