FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017204877> ?p ?o ?g. }

• W2017204877 endingPage "777" @default.
• W2017204877 startingPage "769" @default.
• W2017204877 abstract "Despite histamine being a potent endogenous vasoactive agent released in increasing amounts postburn, its role in postburn oedema formation has been controversial and its effect on burn circulation poorly investigated. The present study investigated the involvement of H(1), H(2) and H(3) receptors in postburn edema in rats exposed to skin and muscle burns and their influence on skin circulation postburn. We used the selective antagonists clemastine (H(1)), ranitidine (H(2)), thioperamide (H(3)) and the selective H(3) receptor agonist, imetit. Results showed that none of the antagonists or the H(3) agonist had significant effect on postburn edema measured by quantitative spectrophotometric analysis of extravasated Evans blue-albumin in the full-thickness burned skin or muscle. Clemastine and thioperamide failed to induce significant effect on blood flow in the partial- or full-thickness skin burn injury as measured by laser Doppler flowmetry, while ranitidine significantly (P<0.01) reduced blood flow in the full-thickness burn. In contrast, the H(3) receptor agonist, imetit, significantly increased blood flow, both in the partial-thickness burn injury (P<0.05) and in the full-thickness burn (P<0.01). Moreover, imetit significantly (P<0.01) increased mean arterial pressure while thioperamide significantly (P<0.01) reduced systemic pressure. In conclusion, H(1), H(2) and H(3) receptors are not important actors in the regulation of vascular patency permeability, whereas H(3) receptors play an important role by increasing skin circulation postburn, presumably by relaxation of vascular smooth muscle and/or by interacting with other inflammatory neurotransmitters. Data also suggest that H(2) receptor blockers may not be best choice for stress ulcer prophylaxis in burn patients." @default.
• W2017204877 created "2016-06-24" @default.
• W2017204877 creator A5003012388 @default.
• W2017204877 creator A5069350228 @default.
• W2017204877 date "2003-12-01" @default.
• W2017204877 modified "2023-09-27" @default.
• W2017204877 title "Role of histamine receptors in the regulation of edema and circulation postburn" @default.
• W2017204877 cites W1966466095 @default.
• W2017204877 cites W1971931005 @default.
• W2017204877 cites W1975970907 @default.
• W2017204877 cites W1988990576 @default.
• W2017204877 cites W1996562508 @default.
• W2017204877 cites W1996875652 @default.
• W2017204877 cites W2004598618 @default.
• W2017204877 cites W2016441440 @default.
• W2017204877 cites W2019944441 @default.
• W2017204877 cites W2028566356 @default.
• W2017204877 cites W2043803127 @default.
• W2017204877 cites W2048533409 @default.
• W2017204877 cites W2060063377 @default.
• W2017204877 cites W2060384694 @default.
• W2017204877 cites W2063618988 @default.
• W2017204877 cites W2067050866 @default.
• W2017204877 cites W2072806252 @default.
• W2017204877 cites W2078596983 @default.
• W2017204877 cites W2081967204 @default.
• W2017204877 cites W2094403074 @default.
• W2017204877 cites W2095462695 @default.
• W2017204877 cites W2103788859 @default.
• W2017204877 cites W2111140103 @default.
• W2017204877 cites W2127824948 @default.
• W2017204877 cites W2138745452 @default.
• W2017204877 cites W2165418705 @default.
• W2017204877 cites W4242989779 @default.
• W2017204877 cites W762789249 @default.
• W2017204877 doi "https://doi.org/10.1016/s0305-4179(03)00203-1" @default.
• W2017204877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14636750" @default.
• W2017204877 hasPublicationYear "2003" @default.
• W2017204877 type Work @default.
• W2017204877 sameAs 2017204877 @default.
• W2017204877 citedByCount "26" @default.
• W2017204877 countsByYear W20172048772012 @default.
• W2017204877 countsByYear W20172048772013 @default.
• W2017204877 countsByYear W20172048772015 @default.
• W2017204877 countsByYear W20172048772016 @default.
• W2017204877 countsByYear W20172048772018 @default.
• W2017204877 countsByYear W20172048772019 @default.
• W2017204877 countsByYear W20172048772021 @default.
• W2017204877 countsByYear W20172048772022 @default.
• W2017204877 countsByYear W20172048772023 @default.
• W2017204877 crossrefType "journal-article" @default.
• W2017204877 hasAuthorship W2017204877A5003012388 @default.
• W2017204877 hasAuthorship W2017204877A5069350228 @default.
• W2017204877 hasConcept C1122143 @default.
• W2017204877 hasConcept C113045295 @default.
• W2017204877 hasConcept C126322002 @default.
• W2017204877 hasConcept C134018914 @default.
• W2017204877 hasConcept C170493617 @default.
• W2017204877 hasConcept C203014093 @default.
• W2017204877 hasConcept C2777445857 @default.
• W2017204877 hasConcept C2778938600 @default.
• W2017204877 hasConcept C2778997900 @default.
• W2017204877 hasConcept C2779540182 @default.
• W2017204877 hasConcept C2780886150 @default.
• W2017204877 hasConcept C42219234 @default.
• W2017204877 hasConcept C63180777 @default.
• W2017204877 hasConcept C71924100 @default.
• W2017204877 hasConceptScore W2017204877C1122143 @default.
• W2017204877 hasConceptScore W2017204877C113045295 @default.
• W2017204877 hasConceptScore W2017204877C126322002 @default.
• W2017204877 hasConceptScore W2017204877C134018914 @default.
• W2017204877 hasConceptScore W2017204877C170493617 @default.
• W2017204877 hasConceptScore W2017204877C203014093 @default.
• W2017204877 hasConceptScore W2017204877C2777445857 @default.
• W2017204877 hasConceptScore W2017204877C2778938600 @default.
• W2017204877 hasConceptScore W2017204877C2778997900 @default.
• W2017204877 hasConceptScore W2017204877C2779540182 @default.
• W2017204877 hasConceptScore W2017204877C2780886150 @default.
• W2017204877 hasConceptScore W2017204877C42219234 @default.
• W2017204877 hasConceptScore W2017204877C63180777 @default.
• W2017204877 hasConceptScore W2017204877C71924100 @default.
• W2017204877 hasIssue "8" @default.
• W2017204877 hasLocation W20172048771 @default.
• W2017204877 hasLocation W20172048772 @default.
• W2017204877 hasOpenAccess W2017204877 @default.
• W2017204877 hasPrimaryLocation W20172048771 @default.
• W2017204877 hasRelatedWork W1965692775 @default.
• W2017204877 hasRelatedWork W1983315707 @default.
• W2017204877 hasRelatedWork W2027913950 @default.
• W2017204877 hasRelatedWork W2034583712 @default.
• W2017204877 hasRelatedWork W2050423574 @default.
• W2017204877 hasRelatedWork W2058205365 @default.
• W2017204877 hasRelatedWork W2063619316 @default.
• W2017204877 hasRelatedWork W2070611629 @default.
• W2017204877 hasRelatedWork W2169225653 @default.
• W2017204877 hasRelatedWork W2172131010 @default.
• W2017204877 hasVolume "29" @default.
• W2017204877 isParatext "false" @default.

• next