Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017219246> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2017219246 endingPage "714" @default.
- W2017219246 startingPage "707" @default.
- W2017219246 abstract "Combination therapy (risperidone and a mood stabilizer) for patients with a history of bipolar disorder (DSM-IV) and hospitalized for treatment of a manic episode was assessed in a 13-week study.Subjects received flexible doses of a mood stabilizer (lithium or divalproex) plus placebo, risperidone, or haloperidol in a 3-week double-blind study. They could then enter a 10-week open-label study during which they received risperidone combined with a mood stabilizer.Of the 156 patients enrolled in the 3-week study, 85 entered the 10-week open-label extension, of whom 48 completed 10 weeks of treatment. The mean +/- SE doses of risperidone were 3.8 +/- 0.3 mg/day during the 3-week study and 3.1 +/- 0.2 mg/day during the 10-week study. At double-blind endpoint, mean reductions in Young Mania Rating Scale (YMRS) scores were significantly greater in patients receiving risperidone plus mood stabilizer than in those receiving placebo plus mood stabilizer (-14.3 vs. -8.2, p <.001). Further significant (p <.001) reductions were seen during the 10 weeks of treatment with risperidone plus mood stabilizer. Symptom remission (YMRS score <or= 12) was seen in 38 patients (79%) at the end of the 10-week study. Scores on the Brief Psychiatric Rating Scale, Hamilton Rating Scale for Depression, and Clinical Global Impressions scale improved significantly (p <.05) during both the 3-week and 10-week studies. Treatment was well tolerated, and modest weight gain was observed during the 13-week study period.The combination of risperidone and a mood stabilizer was efficacious and well tolerated in the continuation treatment of patients initially hospitalized for the management of an acute manic episode." @default.
- W2017219246 created "2016-06-24" @default.
- W2017219246 creator A5007461261 @default.
- W2017219246 creator A5026929668 @default.
- W2017219246 creator A5058588317 @default.
- W2017219246 creator A5080865150 @default.
- W2017219246 date "2004-05-15" @default.
- W2017219246 modified "2023-10-14" @default.
- W2017219246 title "Risperidone in Combination With Mood Stabilizers" @default.
- W2017219246 doi "https://doi.org/10.4088/jcp.v65n0518" @default.
- W2017219246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15163260" @default.
- W2017219246 hasPublicationYear "2004" @default.
- W2017219246 type Work @default.
- W2017219246 sameAs 2017219246 @default.
- W2017219246 citedByCount "41" @default.
- W2017219246 countsByYear W20172192462012 @default.
- W2017219246 countsByYear W20172192462013 @default.
- W2017219246 countsByYear W20172192462019 @default.
- W2017219246 countsByYear W20172192462020 @default.
- W2017219246 countsByYear W20172192462021 @default.
- W2017219246 crossrefType "journal-article" @default.
- W2017219246 hasAuthorship W2017219246A5007461261 @default.
- W2017219246 hasAuthorship W2017219246A5026929668 @default.
- W2017219246 hasAuthorship W2017219246A5058588317 @default.
- W2017219246 hasAuthorship W2017219246A5080865150 @default.
- W2017219246 hasConcept C118552586 @default.
- W2017219246 hasConcept C126322002 @default.
- W2017219246 hasConcept C142724271 @default.
- W2017219246 hasConcept C15744967 @default.
- W2017219246 hasConcept C204787440 @default.
- W2017219246 hasConcept C27081682 @default.
- W2017219246 hasConcept C2776174506 @default.
- W2017219246 hasConcept C2776412080 @default.
- W2017219246 hasConcept C2776466505 @default.
- W2017219246 hasConcept C2776809841 @default.
- W2017219246 hasConcept C2777089681 @default.
- W2017219246 hasConcept C2778528637 @default.
- W2017219246 hasConcept C2778609679 @default.
- W2017219246 hasConcept C2779727114 @default.
- W2017219246 hasConcept C2780051608 @default.
- W2017219246 hasConcept C2780057945 @default.
- W2017219246 hasConcept C2780550438 @default.
- W2017219246 hasConcept C2780733359 @default.
- W2017219246 hasConcept C2908949014 @default.
- W2017219246 hasConcept C71924100 @default.
- W2017219246 hasConceptScore W2017219246C118552586 @default.
- W2017219246 hasConceptScore W2017219246C126322002 @default.
- W2017219246 hasConceptScore W2017219246C142724271 @default.
- W2017219246 hasConceptScore W2017219246C15744967 @default.
- W2017219246 hasConceptScore W2017219246C204787440 @default.
- W2017219246 hasConceptScore W2017219246C27081682 @default.
- W2017219246 hasConceptScore W2017219246C2776174506 @default.
- W2017219246 hasConceptScore W2017219246C2776412080 @default.
- W2017219246 hasConceptScore W2017219246C2776466505 @default.
- W2017219246 hasConceptScore W2017219246C2776809841 @default.
- W2017219246 hasConceptScore W2017219246C2777089681 @default.
- W2017219246 hasConceptScore W2017219246C2778528637 @default.
- W2017219246 hasConceptScore W2017219246C2778609679 @default.
- W2017219246 hasConceptScore W2017219246C2779727114 @default.
- W2017219246 hasConceptScore W2017219246C2780051608 @default.
- W2017219246 hasConceptScore W2017219246C2780057945 @default.
- W2017219246 hasConceptScore W2017219246C2780550438 @default.
- W2017219246 hasConceptScore W2017219246C2780733359 @default.
- W2017219246 hasConceptScore W2017219246C2908949014 @default.
- W2017219246 hasConceptScore W2017219246C71924100 @default.
- W2017219246 hasIssue "5" @default.
- W2017219246 hasLocation W20172192461 @default.
- W2017219246 hasLocation W20172192462 @default.
- W2017219246 hasOpenAccess W2017219246 @default.
- W2017219246 hasPrimaryLocation W20172192461 @default.
- W2017219246 hasRelatedWork W1965265994 @default.
- W2017219246 hasRelatedWork W2000882265 @default.
- W2017219246 hasRelatedWork W2017219246 @default.
- W2017219246 hasRelatedWork W2024158302 @default.
- W2017219246 hasRelatedWork W2025288611 @default.
- W2017219246 hasRelatedWork W2075663229 @default.
- W2017219246 hasRelatedWork W2090784587 @default.
- W2017219246 hasRelatedWork W2093388863 @default.
- W2017219246 hasRelatedWork W2142581464 @default.
- W2017219246 hasRelatedWork W3023984778 @default.
- W2017219246 hasVolume "65" @default.
- W2017219246 isParatext "false" @default.
- W2017219246 isRetracted "false" @default.
- W2017219246 magId "2017219246" @default.
- W2017219246 workType "article" @default.