Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017223932> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2017223932 endingPage "907" @default.
- W2017223932 startingPage "902" @default.
- W2017223932 abstract "Increased 1,25-dihydroxyvitamin D levels and decreased basal and calcium-stimulated calcitonin serum levels have been found in children with Williams-Beuren syndrome (WBS). To determine whether isolated or combined disturbances of secretion or action of the calcium-regulating hormones may cause the tendency to hypercalcemia in WBS, we investigated several aspects of calcium metabolism in 27 normocalcemic children and adults, aged 2 to 47 years, with WBS. With the exception of slightly decreased 25-hydroxyvitamin D and slightly increased calcitonin in serum, all measured basal indexes of calcium and bone metabolism, including the serum levels of intact parathyroid hormone and 1,25-dihydroxyvitamin D, were comparable to control values. Total and extractable calcitonin, the latter representing the monomeric and biologically important form of the hormone, showed the same relative increase after a low-dose calcium infusion in patients and control subjects, indicating a normal capacity of the calcitonin-producing C cells of the thyroid gland in WBS. Furthermore, exogenous parathyroid hormone induced a normal response of 1,25-dihydroxyvitamin D, cyclic adenosine monophosphate, and phosphate excretion, indicating a normal response of the renal 25-hydroxyvitamin D-1 alpha-hydroxylase and the renal receptor-adenylate cyclase system to parathyroid hormone. These findings suggest that neither deficient calcitonin secretion nor increased renal sensitivity to parathyroid hormone is a feature of WBS in normocalcemic patients." @default.
- W2017223932 created "2016-06-24" @default.
- W2017223932 creator A5029428767 @default.
- W2017223932 creator A5032156107 @default.
- W2017223932 creator A5050892393 @default.
- W2017223932 creator A5068850599 @default.
- W2017223932 date "1992-12-01" @default.
- W2017223932 modified "2023-09-26" @default.
- W2017223932 title "Calcium metabolism in Williams-Beuren syndrome" @default.
- W2017223932 cites W1853647023 @default.
- W2017223932 cites W1967516063 @default.
- W2017223932 cites W1968144824 @default.
- W2017223932 cites W1978514323 @default.
- W2017223932 cites W1979556712 @default.
- W2017223932 cites W2004660256 @default.
- W2017223932 cites W2011864174 @default.
- W2017223932 cites W2030181095 @default.
- W2017223932 cites W2046366395 @default.
- W2017223932 cites W2063370308 @default.
- W2017223932 cites W2075368442 @default.
- W2017223932 cites W2081903797 @default.
- W2017223932 cites W2083116747 @default.
- W2017223932 cites W2088535790 @default.
- W2017223932 cites W2093638889 @default.
- W2017223932 cites W2148823426 @default.
- W2017223932 cites W2149722809 @default.
- W2017223932 cites W2985215241 @default.
- W2017223932 cites W317640188 @default.
- W2017223932 doi "https://doi.org/10.1016/s0022-3476(05)80336-1" @default.
- W2017223932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1333009" @default.
- W2017223932 hasPublicationYear "1992" @default.
- W2017223932 type Work @default.
- W2017223932 sameAs 2017223932 @default.
- W2017223932 citedByCount "44" @default.
- W2017223932 countsByYear W20172239322012 @default.
- W2017223932 countsByYear W20172239322013 @default.
- W2017223932 countsByYear W20172239322014 @default.
- W2017223932 countsByYear W20172239322015 @default.
- W2017223932 countsByYear W20172239322016 @default.
- W2017223932 countsByYear W20172239322017 @default.
- W2017223932 countsByYear W20172239322018 @default.
- W2017223932 countsByYear W20172239322021 @default.
- W2017223932 countsByYear W20172239322022 @default.
- W2017223932 countsByYear W20172239322023 @default.
- W2017223932 crossrefType "journal-article" @default.
- W2017223932 hasAuthorship W2017223932A5029428767 @default.
- W2017223932 hasAuthorship W2017223932A5032156107 @default.
- W2017223932 hasAuthorship W2017223932A5050892393 @default.
- W2017223932 hasAuthorship W2017223932A5068850599 @default.
- W2017223932 hasConcept C126322002 @default.
- W2017223932 hasConcept C134018914 @default.
- W2017223932 hasConcept C2778024521 @default.
- W2017223932 hasConcept C2778248654 @default.
- W2017223932 hasConcept C2779306644 @default.
- W2017223932 hasConcept C2779627488 @default.
- W2017223932 hasConcept C2781208988 @default.
- W2017223932 hasConcept C519063684 @default.
- W2017223932 hasConcept C71315377 @default.
- W2017223932 hasConcept C71924100 @default.
- W2017223932 hasConcept C87975464 @default.
- W2017223932 hasConceptScore W2017223932C126322002 @default.
- W2017223932 hasConceptScore W2017223932C134018914 @default.
- W2017223932 hasConceptScore W2017223932C2778024521 @default.
- W2017223932 hasConceptScore W2017223932C2778248654 @default.
- W2017223932 hasConceptScore W2017223932C2779306644 @default.
- W2017223932 hasConceptScore W2017223932C2779627488 @default.
- W2017223932 hasConceptScore W2017223932C2781208988 @default.
- W2017223932 hasConceptScore W2017223932C519063684 @default.
- W2017223932 hasConceptScore W2017223932C71315377 @default.
- W2017223932 hasConceptScore W2017223932C71924100 @default.
- W2017223932 hasConceptScore W2017223932C87975464 @default.
- W2017223932 hasIssue "6" @default.
- W2017223932 hasLocation W20172239321 @default.
- W2017223932 hasLocation W20172239322 @default.
- W2017223932 hasOpenAccess W2017223932 @default.
- W2017223932 hasPrimaryLocation W20172239321 @default.
- W2017223932 hasRelatedWork W1976735578 @default.
- W2017223932 hasRelatedWork W1997645503 @default.
- W2017223932 hasRelatedWork W2021046682 @default.
- W2017223932 hasRelatedWork W2055353584 @default.
- W2017223932 hasRelatedWork W2064236298 @default.
- W2017223932 hasRelatedWork W2070371512 @default.
- W2017223932 hasRelatedWork W2075523373 @default.
- W2017223932 hasRelatedWork W2098049613 @default.
- W2017223932 hasRelatedWork W2335002493 @default.
- W2017223932 hasRelatedWork W2463174084 @default.
- W2017223932 hasVolume "121" @default.
- W2017223932 isParatext "false" @default.
- W2017223932 isRetracted "false" @default.
- W2017223932 magId "2017223932" @default.
- W2017223932 workType "article" @default.