FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017228703> ?p ?o ?g. }

• W2017228703 endingPage "1159" @default.
• W2017228703 startingPage "1147" @default.
• W2017228703 abstract "Time-correlated atomic motions were used to characterize protein domain boundaries from atomic coordinates generated by molecular dynamics simulations. A novel application of the dynamical cross-correlation matrix (DCCM) analysis tool was used to help identify putative protein domains. In implementing this new approach, several DCCM maps were calculated, each using a different coordinate reference frame from which protein domain boundaries and protein domain residue constituents could be identified. Cytochrome P450BM-3, from Bacillus megaterium, was used as the model protein in this study. The analyses indicated that the simulated protein comprises three distinct domain regions; in contrast, only two protein domains were identified in the original crystal structure report. Specifically, the DCCM analyses showed that the F-G helix region was a separate domain entity and not a part of the alpha domain, as previously designated. The simulations demonstrated that the domain motions of the F-G helix region effected both the size and shape of the enzyme active site, and that the dynamics of the F-G helix domain could possibly control access of substrate to the binding pocket." @default.
• W2017228703 created "2016-06-24" @default.
• W2017228703 creator A5025937675 @default.
• W2017228703 creator A5069223890 @default.
• W2017228703 date "1997-09-01" @default.
• W2017228703 modified "2023-09-29" @default.
• W2017228703 title "Molecular dynamics study of time-correlated protein domain motions and molecular flexibility: cytochrome P450BM-3" @default.
• W2017228703 cites W2000051743 @default.
• W2017228703 cites W2076097518 @default.
• W2017228703 cites W2083179556 @default.
• W2017228703 cites W2092504466 @default.
• W2017228703 cites W2106315897 @default.
• W2017228703 cites W2131135498 @default.
• W2017228703 cites W2132589721 @default.
• W2017228703 cites W2132680326 @default.
• W2017228703 cites W2144619577 @default.
• W2017228703 cites W2160451368 @default.
• W2017228703 cites W2166905169 @default.
• W2017228703 doi "https://doi.org/10.1016/s0006-3495(97)78147-5" @default.
• W2017228703 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1181014" @default.
• W2017228703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9284282" @default.
• W2017228703 hasPublicationYear "1997" @default.
• W2017228703 type Work @default.
• W2017228703 sameAs 2017228703 @default.
• W2017228703 citedByCount "77" @default.
• W2017228703 countsByYear W20172287032012 @default.
• W2017228703 countsByYear W20172287032014 @default.
• W2017228703 countsByYear W20172287032015 @default.
• W2017228703 countsByYear W20172287032016 @default.
• W2017228703 countsByYear W20172287032017 @default.
• W2017228703 countsByYear W20172287032018 @default.
• W2017228703 countsByYear W20172287032019 @default.
• W2017228703 countsByYear W20172287032020 @default.
• W2017228703 countsByYear W20172287032021 @default.
• W2017228703 countsByYear W20172287032022 @default.
• W2017228703 countsByYear W20172287032023 @default.
• W2017228703 crossrefType "journal-article" @default.
• W2017228703 hasAuthorship W2017228703A5025937675 @default.
• W2017228703 hasAuthorship W2017228703A5069223890 @default.
• W2017228703 hasBestOaLocation W20172287031 @default.
• W2017228703 hasConcept C104317684 @default.
• W2017228703 hasConcept C121332964 @default.
• W2017228703 hasConcept C12554922 @default.
• W2017228703 hasConcept C134306372 @default.
• W2017228703 hasConcept C144292202 @default.
• W2017228703 hasConcept C147597530 @default.
• W2017228703 hasConcept C185592680 @default.
• W2017228703 hasConcept C186060115 @default.
• W2017228703 hasConcept C18903297 @default.
• W2017228703 hasConcept C2778530040 @default.
• W2017228703 hasConcept C2779965526 @default.
• W2017228703 hasConcept C2780989563 @default.
• W2017228703 hasConcept C28859421 @default.
• W2017228703 hasConcept C29311851 @default.
• W2017228703 hasConcept C33923547 @default.
• W2017228703 hasConcept C36503486 @default.
• W2017228703 hasConcept C47701112 @default.
• W2017228703 hasConcept C523546767 @default.
• W2017228703 hasConcept C54355233 @default.
• W2017228703 hasConcept C55493867 @default.
• W2017228703 hasConcept C59593255 @default.
• W2017228703 hasConcept C70721500 @default.
• W2017228703 hasConcept C8010536 @default.
• W2017228703 hasConcept C86803240 @default.
• W2017228703 hasConceptScore W2017228703C104317684 @default.
• W2017228703 hasConceptScore W2017228703C121332964 @default.
• W2017228703 hasConceptScore W2017228703C12554922 @default.
• W2017228703 hasConceptScore W2017228703C134306372 @default.
• W2017228703 hasConceptScore W2017228703C144292202 @default.
• W2017228703 hasConceptScore W2017228703C147597530 @default.
• W2017228703 hasConceptScore W2017228703C185592680 @default.
• W2017228703 hasConceptScore W2017228703C186060115 @default.
• W2017228703 hasConceptScore W2017228703C18903297 @default.
• W2017228703 hasConceptScore W2017228703C2778530040 @default.
• W2017228703 hasConceptScore W2017228703C2779965526 @default.
• W2017228703 hasConceptScore W2017228703C2780989563 @default.
• W2017228703 hasConceptScore W2017228703C28859421 @default.
• W2017228703 hasConceptScore W2017228703C29311851 @default.
• W2017228703 hasConceptScore W2017228703C33923547 @default.
• W2017228703 hasConceptScore W2017228703C36503486 @default.
• W2017228703 hasConceptScore W2017228703C47701112 @default.
• W2017228703 hasConceptScore W2017228703C523546767 @default.
• W2017228703 hasConceptScore W2017228703C54355233 @default.
• W2017228703 hasConceptScore W2017228703C55493867 @default.
• W2017228703 hasConceptScore W2017228703C59593255 @default.
• W2017228703 hasConceptScore W2017228703C70721500 @default.
• W2017228703 hasConceptScore W2017228703C8010536 @default.
• W2017228703 hasConceptScore W2017228703C86803240 @default.
• W2017228703 hasIssue "3" @default.
• W2017228703 hasLocation W20172287031 @default.
• W2017228703 hasLocation W20172287032 @default.
• W2017228703 hasLocation W20172287033 @default.
• W2017228703 hasLocation W20172287034 @default.
• W2017228703 hasOpenAccess W2017228703 @default.
• W2017228703 hasPrimaryLocation W20172287031 @default.
• W2017228703 hasRelatedWork W1963675638 @default.
• W2017228703 hasRelatedWork W1994435755 @default.
• W2017228703 hasRelatedWork W2007662810 @default.

• next