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- W2017230061 abstract "The aim of this study was to investigate molecular interactions between Quil A and phosphatidylcholine in the solid state using diffuse reflectance infrared Fourier-transform spectroscopy (DRIFTS). Analysis of the interactions was characterized on the different regions of phosphatidylcholine: hydrophobic chain, interfacial and headgroup regions. The spectra of the hydrocarbon region of phosphatidylcholine alone compared to that for the binary mixture of Quil A and phosphatidylcholine were similar. These findings suggest that Quil A did not cause conformational disorder of the fatty acyl chains of the phospholipid. In contrast, a shift in the wavenumber of the choline group and a broad band in this moiety indicate a modification of the phospholipid in the headgroup region due to interaction between Quil A and phosphatidylcholine. These results suggest possibly ionic interactions between the negatively charged glucuronic acid moiety of the Quil A molecule with the positively charged choline group. The findings could also be the result of conformational changes in the choline group because of the intercalation of sugar moieties in Quil A between the choline and phosphate groups due to hydrogen bonding. Shift of wavenumbers to lower values on the carbonyl group was observed suggesting hydrogen bonding between Quil A and phosphatidylcholine. The difference in degrees of wavenumber shift (choline>phosphate>carbonyl group) and observed broad bands indicated that Quil A preferentially interacted with phosphatidylcholine on the hydrophilic headgroup. Cholesterol influenced such interactions at relatively high concentration (60%, w/w)." @default.
- W2017230061 created "2016-06-24" @default.
- W2017230061 creator A5013406378 @default.
- W2017230061 creator A5024535039 @default.
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- W2017230061 creator A5073186051 @default.
- W2017230061 date "2007-09-01" @default.
- W2017230061 modified "2023-10-14" @default.
- W2017230061 title "Analysis of Quil A–phospholipid mixtures using drift spectroscopy" @default.
- W2017230061 cites W1555200283 @default.
- W2017230061 cites W1800786347 @default.
- W2017230061 cites W1963877178 @default.
- W2017230061 cites W1966013999 @default.
- W2017230061 cites W1969463148 @default.
- W2017230061 cites W1969605397 @default.
- W2017230061 cites W1969782573 @default.
- W2017230061 cites W1970072617 @default.
- W2017230061 cites W1971226541 @default.
- W2017230061 cites W1976659288 @default.
- W2017230061 cites W1977000801 @default.
- W2017230061 cites W1977727325 @default.
- W2017230061 cites W1979146520 @default.
- W2017230061 cites W1983064628 @default.
- W2017230061 cites W1983470179 @default.
- W2017230061 cites W1986611161 @default.
- W2017230061 cites W1992269173 @default.
- W2017230061 cites W1992479586 @default.
- W2017230061 cites W1998476468 @default.
- W2017230061 cites W1999021723 @default.
- W2017230061 cites W1999232203 @default.
- W2017230061 cites W1999560762 @default.
- W2017230061 cites W1999578484 @default.
- W2017230061 cites W2000503283 @default.
- W2017230061 cites W2003255768 @default.
- W2017230061 cites W2004029903 @default.
- W2017230061 cites W2004650663 @default.
- W2017230061 cites W2004759340 @default.
- W2017230061 cites W2006028725 @default.
- W2017230061 cites W2007105570 @default.
- W2017230061 cites W2009306474 @default.
- W2017230061 cites W2014356384 @default.
- W2017230061 cites W2016682415 @default.
- W2017230061 cites W2018208145 @default.
- W2017230061 cites W2018234070 @default.
- W2017230061 cites W2022733171 @default.
- W2017230061 cites W2024147966 @default.
- W2017230061 cites W2024642029 @default.
- W2017230061 cites W2025372248 @default.
- W2017230061 cites W2028045919 @default.
- W2017230061 cites W2028323006 @default.
- W2017230061 cites W2031997066 @default.
- W2017230061 cites W2034191594 @default.
- W2017230061 cites W2038500672 @default.
- W2017230061 cites W2043619106 @default.
- W2017230061 cites W2048175618 @default.
- W2017230061 cites W2052177037 @default.
- W2017230061 cites W2053970211 @default.
- W2017230061 cites W2057010810 @default.
- W2017230061 cites W2058391922 @default.
- W2017230061 cites W2060812776 @default.
- W2017230061 cites W2063926986 @default.
- W2017230061 cites W2065945804 @default.
- W2017230061 cites W2067909435 @default.
- W2017230061 cites W2068415635 @default.
- W2017230061 cites W2068865225 @default.
- W2017230061 cites W2069929345 @default.
- W2017230061 cites W2070354739 @default.
- W2017230061 cites W2074317725 @default.
- W2017230061 cites W2076834198 @default.
- W2017230061 cites W2077048311 @default.
- W2017230061 cites W2078473516 @default.
- W2017230061 cites W2081952922 @default.
- W2017230061 cites W2085183163 @default.
- W2017230061 cites W2085592625 @default.
- W2017230061 cites W2094868581 @default.
- W2017230061 cites W2135823791 @default.
- W2017230061 cites W2139681368 @default.
- W2017230061 cites W2164397319 @default.
- W2017230061 cites W2319540709 @default.
- W2017230061 cites W2913804396 @default.
- W2017230061 cites W4230342171 @default.
- W2017230061 cites W50419558 @default.
- W2017230061 doi "https://doi.org/10.1016/j.ijpharm.2007.04.030" @default.
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